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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:salsalate
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Accession:CHEBI:9014 term browser browse the term
Definition:A dimeric benzoate ester obtained by intermolecular condensation between the carboxy of one molecule of salicylic acid with the phenol group of a second. It is a prodrug for salycylic acid that is used for treatment of rheumatoid arthritis and osteoarthritis and also shows activity against type II diabetes.
Synonyms:exact_synonym: 2-[(2-hydroxybenzoyl)oxy]benzoic acid
 related_synonym: 2-Carboxyphenyl salicylate;   Disalcid;   Disalicylic acid;   Disalicylsaeure;   Formula=C14H10O5;   InChI=1S/C14H10O5/c15-11-7-3-1-5-9(11)14(18)19-12-8-4-2-6-10(12)13(16)17/h1-8,15H,(H,16,17);   InChIKey=WVYADZUPLLSGPU-UHFFFAOYSA-N;   O-Salicylcylsalicylsaeure;   SMILES=OC(=O)c1ccccc1OC(=O)c1ccccc1O;   Salicylic acid bimolecular ester;   Salicyloxysalicylic acid;   Salicyloylsalicylic acid;   Sasapyrin;   Sasapyrine;   Sasapyrinum;   o-Salicylsalicylic acid;   salicylsalicylic acid;   salsalato;   salsalatum
 xref: CAS:552-94-3;   DrugBank:DB01399;   Drug_Central:2420;   KEGG:D00428
 xref_mesh: MESH:C014182
 xref: PMID:19747808;   PMID:20613460;   PMID:20876710;   PMID:21289240;   PMID:21519323;   PMID:21617098;   PMID:21764223;   PMID:21903749;   PMID:21938543;   PMID:22357964;   PMID:22388922;   PMID:22517326;   PMID:22782506;   PMID:22784842;   PMID:23370525;   PMID:23680037;   PMID:23801715;   PMID:23817699;   PMID:23817718;   PMID:23825542;   PMID:23871515;   PMID:23948064;   PMID:24130358;   PMID:28166217;   Reaxys:2590908;   Wikipedia:Salsalate


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Path 1
Term Annotations click to browse term
  CHEBI ontology 499
    role 499
      application 457
        pro-agent 17
          prodrug 17
            salsalate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 499
    subatomic particle 499
      composite particle 499
        hadron 499
          baryon 499
            nucleon 499
              atomic nucleus 499
                atom 499
                  main group element atom 492
                    p-block element atom 492
                      carbon group element atom 481
                        carbon atom 480
                          organic molecular entity 480
                            heteroorganic entity 476
                              organochalcogen compound 430
                                organooxygen compound 428
                                  carbon oxoacid 368
                                    carboxylic acid 368
                                      aromatic carboxylic acid 19
                                        benzoic acids 16
                                          benzoic acid 2
                                            hydroxybenzoic acid 2
                                              monohydroxybenzoic acid 2
                                                salicylic acid 2
                                                  salsalate 0
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