Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Salidroside
go back to main search page
Accession:CHEBI:9009 term browser browse the term
Definition:A glycoside that has formula C14H20O7.
Synonyms:related_synonym: Formula=C14H20O7;   InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1;   InChIKey=ILRCGYURZSFMEG-RKQHYHRCSA-N;   SMILES=OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O;   Tyrosol glucoside;   p-Hydroxyphenethyl alcohol 1-O-beta-D-glucoside
 xref: CAS:10338-51-9;   KEGG:C06046
 xref_mesh: MESH:C009172


show annotations for term's descendants           Sort by:
 
Salidroside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO [furan co-treated with rhodioloside] results in increased expression of ABCB11 mRNA CTD PMID:32251705 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO rhodioloside affects the reaction [ABCB1 protein results in increased transport of Digoxin] CTD PMID:24380838 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein]]; rhodioloside inhibits the reaction [Colistin results in decreased phosphorylation of AKT1 protein] CTD PMID:28465020 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases activity
increases expression
ISO rhodioloside results in increased activity of ALPL protein
rhodioloside results in increased expression of ALPL mRNA
CTD PMID:24055767 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]
rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in increased expression of BAX protein]]; rhodioloside inhibits the reaction [cobaltous chloride results in increased expression of BAX protein]; rhodioloside inhibits the reaction [Colistin results in increased expression of BAX protein]; rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]; rhodioloside inhibits the reaction [Doxorubicin results in increased expression of BAX protein]
CTD PMID:21499890 PMID:24072175 PMID:28465020 PMID:28851138 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO
EXP
rhodioloside results in increased expression of BCL2 mRNA
rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in decreased expression of BCL2 protein]]; rhodioloside inhibits the reaction [Colistin results in decreased expression of BCL2 protein]; rhodioloside inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]
rhodioloside results in increased expression of BCL2 protein
CTD PMID:24072175 PMID:28465020 PMID:28851138 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO rhodioloside results in increased expression of BMP2 mRNA CTD PMID:24055767 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO rhodioloside results in increased expression of BMP6 mRNA CTD PMID:24055767 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression ISO rhodioloside results in increased expression of BMP7 mRNA CTD PMID:24055767 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Casp1 caspase 1 multiple interactions EXP rhodioloside inhibits the reaction [Glucose results in increased expression of CASP1 protein] CTD PMID:29031534 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [rhodioloside inhibits the reaction [Colistin results in increased activity of and results in increased cleavage of CASP3 protein]]; rhodioloside inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; rhodioloside inhibits the reaction [Colistin results in increased activity of and results in increased cleavage of CASP3 protein]; rhodioloside inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]
rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]]
CTD PMID:24072175 PMID:28465020 PMID:28851138 PMID:30991096 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO
EXP
rhodioloside results in increased expression of CAT mRNA; rhodioloside results in increased expression of CAT protein
rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
CTD PMID:24072175 PMID:31682803 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein] CTD PMID:31682803 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cert1 ceramide transporter 1 multiple interactions EXP rhodioloside inhibits the reaction [Glucose results in increased expression of CERT1 mRNA] CTD PMID:29031534 NCBI chr 2:27,365,145...27,469,797
Ensembl chr 2:27,365,148...27,469,779
JBrowse link
G Cldn11 claudin 11 multiple interactions ISO rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein] CTD PMID:31682803 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NOX2 protein]; sirtinol inhibits the reaction [rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NOX2 protein]] CTD PMID:28851138 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in decreased expression of CYP7A1 mRNA] CTD PMID:32251705 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions EXP rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein] CTD PMID:24989011 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Eno2 enolase 2 multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 protein]
rhodioloside results in increased expression of ENO2 mRNA; rhodioloside results in increased expression of ENO2 protein
CTD PMID:24929042 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
Ensembl chr 9:157,285,179...157,294,047
JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions ISO [furan co-treated with rhodioloside] results in increased expression of FGF15 mRNA CTD PMID:32251705 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP rhodioloside inhibits the reaction [Glucose results in increased expression of FN1 mRNA] CTD PMID:29031534 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression ISO rhodioloside results in decreased expression of HES1 mRNA CTD PMID:24929042 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions EXP [rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA; R 59949 inhibits the reaction [rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein]; rhodioloside promotes the reaction [cobaltous chloride results in increased expression of and affects the localization of HIF1A protein] CTD PMID:21499890 PMID:24989011 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 protein]
rhodioloside results in increased expression of MAP2 mRNA; rhodioloside results in increased expression of MAP2 protein
CTD PMID:24929042 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein] CTD PMID:24989011 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Ngf nerve growth factor multiple interactions EXP [rhodioloside co-treated with cobaltous chloride co-treated with NGF protein] results in decreased expression of HIF1A mRNA; Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]; Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 mRNA]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of DDIT4 protein]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in increased expression of HIF1A protein] CTD PMID:24989011 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP rhodioloside inhibits the reaction [Glucose results in increased expression of NLRP3 protein] CTD PMID:29031534 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nog noggin multiple interactions ISO NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of ENO2 protein]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of MAP2 protein]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 protein] CTD PMID:24929042 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Notch1 notch receptor 1 decreases expression ISO rhodioloside results in decreased expression of NOTCH1 mRNA CTD PMID:24929042 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO
EXP
rhodioloside inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA] CTD PMID:24072175 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions ISO rhodioloside inhibits the reaction [furan results in increased expression of NR0B2 mRNA] CTD PMID:32251705 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO rhodioloside affects the reaction [furan affects the expression of NR1H4 mRNA] CTD PMID:32251705 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Ocln occludin multiple interactions ISO rhodioloside affects the reaction [furan results in decreased expression of OCLN protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of OCLN protein] CTD PMID:31682803 PMID:32251705 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta multiple interactions EXP rhodioloside inhibits the reaction [[Oxygen co-treated with Glucose deficiency] results in decreased expression of PRKAR2B protein] CTD PMID:24726522 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions EXP rhodioloside inhibits the reaction [Glucose results in increased expression of PYCARD protein] CTD PMID:29031534 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP rhodioloside inhibits the reaction [cobaltous chloride results in increased expression of RELA protein] CTD PMID:21499890 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]; rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:24989011 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression
increases activity
ISO rhodioloside results in increased expression of RUNX2 mRNA
rhodioloside results in increased activity of RUNX2 protein
CTD PMID:24055767 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO rhodioloside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of and results in decreased activity of SIRT1 protein] CTD PMID:28851138 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Smad1 SMAD family member 1 multiple interactions
increases expression
ISO rhodioloside results in increased phosphorylation of and results in increased expression of SMAD1 protein
rhodioloside results in increased expression of SMAD1 mRNA
CTD PMID:24929042 NCBI chr19:32,182,942...32,248,694
Ensembl chr19:32,188,267...32,248,684
JBrowse link
G Smad5 SMAD family member 5 increases expression
multiple interactions
ISO rhodioloside results in increased expression of SMAD5 mRNA
rhodioloside results in increased phosphorylation of and results in increased expression of SMAD5 protein
CTD PMID:24929042 NCBI chr17:8,307,448...8,336,996
Ensembl chr17:8,311,796...8,331,032
JBrowse link
G Smad9 SMAD family member 9 increases expression
multiple interactions
ISO rhodioloside results in increased expression of SMAD9 mRNA
rhodioloside results in increased phosphorylation of and results in increased expression of SMAD9 protein
CTD PMID:24929042 NCBI chr 2:143,951,725...144,002,025
Ensembl chr 2:144,191,846...144,212,138
Ensembl chr 2:144,191,846...144,212,138
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO
EXP
rhodioloside results in increased expression of SOD2 mRNA; rhodioloside results in increased expression of SOD2 protein CTD PMID:24072175 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sp7 Sp7 transcription factor increases expression ISO rhodioloside results in increased expression of SP7 mRNA CTD PMID:24055767 NCBI chr 7:143,957,316...143,967,488
Ensembl chr 7:143,958,858...143,967,484
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO rhodioloside results in increased expression of SPP1 mRNA CTD PMID:24055767 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP rhodioloside inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; rhodioloside inhibits the reaction [Paraquat results in increased expression of TGFB1 protein] CTD PMID:25674253 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO rhodioloside inhibits the reaction [furan results in decreased expression of TJP1 protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of TJP1 protein] CTD PMID:31682803 PMID:32251705 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester promotes the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 mRNA]; NOG protein inhibits the reaction [rhodioloside results in increased expression of TUBB3 protein]
rhodioloside results in increased expression of TUBB3 mRNA; rhodioloside results in increased expression of TUBB3 protein
CTD PMID:24929042 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions EXP rhodioloside inhibits the reaction [Glucose results in increased expression of TXNIP protein] CTD PMID:29031534 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      atom 19771
        nonmetal atom 19654
          oxygen atom 19357
            oxygen molecular entity 19357
              organooxygen compound 18879
                carbohydrates and carbohydrate derivatives 12262
                  carbohydrate derivative 11892
                    glycosyl compound 10963
                      glycoside 9256
                        Salidroside 49
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            heteroorganic entity 19208
                              organochalcogen compound 18953
                                organooxygen compound 18879
                                  carbohydrates and carbohydrate derivatives 12262
                                    carbohydrate 12262
                                      carbohydrate derivative 11892
                                        glycosyl compound 10963
                                          glycoside 9256
                                            Salidroside 49
paths to the root