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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:8-Hydroxyguanosine
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Accession:CHEBI:90031 term browser browse the term
Definition:A purine nucleoside that has formula C10H13N5O6.
Synonyms:related_synonym: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,7,8,9-tetrahydro-1H-purine-6,8-dione;   7,8-Dihydro-8-oxo-Guanosine;   8-Oxoguanosine;   Formula=C10H13N5O6;   InChI=1S/C10H13N5O6/c11-9-13-6-3(7(19)14-9)12-10(20)15(6)8-5(18)4(17)2(1-16)21-8/h2,4-5,8,16-18H,1H2,(H,12,20)(H3,11,13,14,19)/t2-,4-,5-,8-/m1/s1;   InChIKey=FPGSEBKFEJEOSA-UMMCILCDSA-N;   Purine-6,8(1H,9H)-dione, 2-amino-9-.beta.-D-ribofuranosyl- (7CI,8CI);   Purine-6,8(1H,9H)-dione, 2-amino-9-.beta.-delta-ribofuranosyl- (7CI,8CI);   SMILES=N1([C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(NC=3C(NC(=NC13)N)=O)=O
 xref: CAS:3868-31-3;   HMDB:HMDB0002044
 xref_mesh: MESH:C046215
 xref: PMID:12391605;   PMID:12499051;   PMID:12546425;   PMID:14607529



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8-Hydroxyguanosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor multiple interactions
increases abundance
EXP Acetylcysteine inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine]; Selenium inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine] CTD PMID:11158190 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          nitrogen atom 18767
            nitrogen molecular entity 18767
              nucleobase-containing molecular entity 5381
                nucleoside 5381
                  purine nucleoside 591
                    8-Hydroxyguanosine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organochalcogen compound 19052
                                organooxygen compound 18998
                                  carbohydrates and carbohydrate derivatives 12342
                                    carbohydrate 12342
                                      carbohydrate derivative 11946
                                        glycosyl compound 10983
                                          N-glycosyl compound 5520
                                            nucleoside 5381
                                              purine nucleoside 591
                                                8-Hydroxyguanosine 1
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