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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyclotetradecane
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Accession:CHEBI:89715 term browser browse the term
Definition:A cycloalkane that consists of fourteen carbons each bonded with two hydrogens.
Synonyms:related_synonym: Formula=C14H28;   InChI=1S/C14H28/c1-2-4-6-8-10-12-14-13-11-9-7-5-3-1/h1-14H2;   InChIKey=KATXJJSCAPBIOB-UHFFFAOYSA-N;   SMILES=C1CCCCCCCCCCCCC1
 xref: CAS:295-17-0;   FooDB:FDB011637;   HMDB:HMDB0033567;   PMID:16002169;   PMID:24260553;   PMID:24421258;   PMID:29034429;   Wikipedia:Cyclotetradecane



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plerixafor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO
plerixafor inhibits the reaction [naringin results in increased phosphorylation of AKT1 protein]
plerixafor inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]
CTD PMID:18660423 PMID:29510123 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO plerixafor inhibits the reaction [bisphenol A results in decreased expression of CDH1 protein]; plerixafor inhibits the reaction [Estradiol results in decreased expression of CDH1 protein]; plerixafor inhibits the reaction [Triclosan results in decreased expression of CDH1 protein] CTD PMID:28844962 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression
ISO plerixafor inhibits the reaction [CXCL12 protein affects the localization of CXCR4 protein]; plerixafor inhibits the reaction [CXCL12 protein results in increased phosphorylation of AKT1 protein]; plerixafor inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein]
plerixafor results in decreased expression of CXCL12 mRNA
CTD PMID:12220670 PMID:18660423 PMID:24157575 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases activity
decreases expression
multiple interactions
ISO plerixafor results in decreased activity of CXCR4 protein
plerixafor results in decreased expression of CXCR4 protein
plerixafor binds to and results in decreased activity of CXCR4 protein; plerixafor inhibits the reaction [bisphenol A results in increased expression of CXCR4 protein]; plerixafor inhibits the reaction [CXCL12 protein affects the localization of CXCR4 protein]; plerixafor inhibits the reaction [Estradiol results in increased expression of CXCR4 protein]; plerixafor inhibits the reaction [Triclosan results in increased expression of CXCR4 protein]
CTD PMID:12220670 PMID:17121897 PMID:28844962 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO plerixafor inhibits the reaction [CXCL12 protein results in increased phosphorylation of NOS3 protein] CTD PMID:18660423 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions ISO plerixafor inhibits the reaction [bisphenol A results in increased expression of SNAI2 protein]; plerixafor inhibits the reaction [Estradiol results in increased expression of SNAI2 protein]; plerixafor inhibits the reaction [Triclosan results in increased expression of SNAI2 protein] CTD PMID:28844962 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Particulate Matter results in decreased susceptibility to [VEGFA protein modified form co-treated with plerixafor]
plerixafor inhibits the reaction [cobaltous chloride results in increased secretion of VEGFA protein]
CTD PMID:22418586 PMID:25815440 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            eukaryotic metabolite 19033
              plant metabolite 17450
                cyclotetradecane 7
                  1,4,8,11-tetraazacyclotetradecane + 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon group molecular entity 19619
                          organic molecular entity 19609
                            organic molecule 19549
                              organic cyclic compound 19343
                                carbocyclic compound 18316
                                  cyclic hydrocarbon 17069
                                    monocyclic hydrocarbon 5845
                                      cycloalkane 509
                                        cyclotetradecane 7
                                          1,4,8,11-tetraazacyclotetradecane + 7
paths to the root