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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-methoxytyramine
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Accession:CHEBI:89641 term browser browse the term
Definition:A monomethoxybenzene that is dopamine in which the hydroxy group at position 4 is replaced by a methoxy group.
Synonyms:related_synonym: 2-(3-hydroxy-4-methoxyphenyl)ethylamine;   3-Hydroxy-4-methoxyphenethylamine;   3-hydroxy-4-methoxyphenylethylamine;   4-O-Methyldopamine;   4-methoxy-3-hydroxyphenethylamine;   4-methoxy-3-hydroxyphenylethylamine;   4-methoxy-m-tyramine;   4-methoxydopamine;   5-(2-aminoethyl)-2-methoxyphenol;   5-(2-aminoethyl)guaiacol;   5-Hydroxy-4-methoxy-Benzeneethanamine;   Formula=C9H13NO2;   InChI=1S/C9H13NO2/c1-12-9-3-2-7(4-5-10)6-8(9)11/h2-3,6,11H,4-5,10H2,1H3;   InChIKey=WJXQFVMTIGJBFX-UHFFFAOYSA-N;   SMILES=COC1=C(O)C=C(CCN)C=C1;   p-methoxydopamine
 xref: CAS:3213-30-7;   FooDB:FDB028818;   HMDB:HMDB0012162
 xref_mesh: MESH:C031065
 xref: PMID:10850391;   PMID:12495814;   PMID:12777961;   PMID:1400795;   PMID:18077578;   PMID:21090691;   PMID:3860259;   PMID:404066;   PMID:4403838;   PMID:541405;   PMID:6060260;   PMID:6113986;   PMID:6518609;   PMID:6824696;   PMID:8113819
 cyclic_relationship: is_conjugate_base_of CHEBI:192993



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4-methoxytyramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions
ISO 3-hydroxy-4-methoxyphenethylamine results in increased activity of TAAR1 protein
[3-hydroxy-4-methoxyphenethylamine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP
CTD PMID:19725810 NCBI chr 1:21,517,742...21,518,740
Ensembl chr 1:21,517,258...21,532,084
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      biological role 19808
        molecular messenger 18637
          monoamine molecular messenger 610
            catecholamine 556
              dopamine 377
                4-methoxytyramine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    main group molecular entity 19782
                      s-block molecular entity 19620
                        hydrogen molecular entity 19607
                          hydrides 19105
                            inorganic hydride 18113
                              pnictogen hydride 18102
                                nitrogen hydride 18009
                                  azane 17819
                                    ammonia 17818
                                      organic amino compound 17818
                                        aralkylamino compound 1008
                                          monoamine 610
                                            monoamine molecular messenger 610
                                              catecholamine 556
                                                dopamine 377
                                                  4-methoxytyramine 1
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