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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,4-di-tert-butylphenol
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Accession:CHEBI:89188 term browser browse the term
Definition:A member of the class of phenols carrying two tert-butyl substituents at positions 2 and 4.
Synonyms:related_synonym: 1-Hydroxy-2,4-di-tert-butylbenzene;   2,4-Bis(1,1-dimethylethyl)phenol;   2,4-Bis(tert-butyl)phenol;   2,4-Di-t-Butylphenol;   2,4-Tert-butylphenol;   Formula=C14H22O;   InChI=1S/C14H22O/c1-13(2,3)10-7-8-12(15)11(9-10)14(4,5)6/h7-9,15H,1-6H3;   InChIKey=ICKWICRCANNIBI-UHFFFAOYSA-N;   SMILES=OC1=CC=C(C(C)(C)C)C=C1C(C)(C)C
 xref: Beilstein:1910383;   CAS:96-76-4;   HMDB:HMDB0013816
 xref_mesh: MESH:C056559
 xref: PMID:16595909;   PMID:22020168;   PMID:23450232;   PMID:24074359;   PMID:24934765;   PMID:25641715;   PMID:27107984;   PMID:27524650;   Reaxys:1910383



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2,4-di-tert-butylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esrrg estrogen-related receptor gamma increases activity ISO 2,4-di-tert-butylphenol results in increased activity of ESRRG protein CTD PMID:31127318 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO 2,4-di-tert-butylphenol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2] results in increased expression of KEAP1 mRNA CTD PMID:36682590 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Meox1 mesenchyme homeobox 1 multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in decreased expression of MEOX1 mRNA CTD PMID:36682590 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
JBrowse link
G Nanog Nanog homeobox multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in increased expression of NANOG mRNA CTD PMID:36682590 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Pax3 paired box 3 multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in decreased expression of PAX3 mRNA CTD PMID:36682590 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pax9 paired box 9 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2] results in decreased expression of PAX9 mRNA CTD PMID:36682590 NCBI chr 6:74,186,749...74,203,508
Ensembl chr 6:74,182,568...74,203,506
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in increased expression of POU5F1 mRNA CTD PMID:36682590 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of RUNX2 mRNA CTD PMID:36682590 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sp7 Sp7 transcription factor multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of SP7 mRNA CTD PMID:36682590 NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [SAG compound co-treated with 2,4-di-tert-butylphenol co-treated with Fibroblast Growth Factor 2 co-treated with Ascorbic Acid co-treated with alpha-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA CTD PMID:36682590 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tbx6 T-box transcription factor 6 multiple interactions ISO [Chir 99021 co-treated with 2,4-di-tert-butylphenol] results in decreased expression of TBX6 mRNA CTD PMID:36682590 NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO 2,4-di-tert-butylphenol results in increased activity of TRPA1 protein CTD PMID:21591660 PMID:29658714 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 increases activity ISO 2,4-di-tert-butylphenol results in increased activity of TRPV3 protein CTD PMID:29658714 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296
JBrowse link

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  CHEBI ontology 19918
    role 19894
      chemical role 19512
        antioxidant 16062
          2,4-di-tert-butylphenol 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    main group molecular entity 19866
                      s-block molecular entity 19698
                        hydrogen molecular entity 19684
                          hydrides 19159
                            organic hydride 18714
                              organic fundamental parent 18714
                                hydrocarbon 18440
                                  cyclic hydrocarbon 17255
                                    monocyclic hydrocarbon 6146
                                      annulene 5796
                                        aromatic annulene 5796
                                          benzene 5796
                                            alkylbenzene 3507
                                              2,4-di-tert-butylphenol 14
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