Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:robinetin
go back to main search page
Accession:CHEBI:8876 term browser browse the term
Definition:A pentahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 7, 3, 4' and 5'.
Synonyms:exact_synonym: 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one
 related_synonym: 5-Deoxymyricetin;   5-Hydroxyfisetin;   Formula=C15H10O7;   InChI=1S/C15H10O7/c16-7-1-2-8-11(5-7)22-15(14(21)12(8)19)6-3-9(17)13(20)10(18)4-6/h1-5,16-18,20-21H;   InChIKey=SOEDEYVDCDYMMH-UHFFFAOYSA-N;   SMILES=Oc1ccc2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O
 xref: AGR:IND500888184;   CAS:490-31-3;   KEGG:C10177;   KNApSAcK:C00001092
 xref_mesh: MESH:C040014
 xref: PMID:16132219;   PMID:19914085;   PMID:25313717;   PMID:25482106;   Reaxys:308905


show annotations for term's descendants           Sort by:
 
robinetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
ISO robinetin results in decreased activity of ABCC1 protein
robinetin inhibits the reaction [ABCC1 protein affects the export of fluorexon]
CTD PMID:15670588 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases activity
ISO robinetin inhibits the reaction [ABCC2 protein affects the export of fluorexon]
robinetin results in decreased activity of ABCC2 protein
CTD PMID:15670588 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR gene mutant form inhibits the reaction [robinetin results in increased expression of CYP1A1 mRNA]; AHR gene mutant form inhibits the reaction [robinetin results in increased expression of UGT1A1 mRNA] CTD PMID:29584932 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO AHR gene mutant form inhibits the reaction [robinetin results in increased expression of CYP1A1 mRNA]
robinetin results in increased expression of CYP1A1 mRNA; robinetin results in increased expression of CYP1A1 protein
CTD PMID:29584932 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions
increases expression
ISO AHR gene mutant form inhibits the reaction [robinetin results in increased expression of UGT1A1 mRNA] CTD PMID:29584932 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        biochemical role 19313
          metabolite 19294
            eukaryotic metabolite 18943
              plant metabolite 17424
                robinetin 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic heterocyclic compound 18432
                                  oxacycle 17200
                                    benzopyran 10142
                                      1-benzopyran 9858
                                        flavonoid 6376
                                          flavones 4169
                                            hydroxyflavone 4157
                                              flavonols 4071
                                                7-hydroxyflavonol 4050
                                                  robinetin 5
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.