|
G |
Ace |
angiotensin I converting enzyme |
multiple interactions |
EXP |
Rivastigmine inhibits the reaction [Colchicine results in decreased expression of ACE protein] |
CTD |
PMID:17652827 |
|
NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
|
|
G |
Ache |
acetylcholinesterase |
affects activity decreases activity multiple interactions |
EXP ISO |
Rivastigmine affects the activity of ACHE protein Rivastigmine results in decreased activity of ACHE protein AFDX 384 affects the reaction [Rivastigmine affects the activity of ACHE protein] |
CTD |
PMID:12111444 PMID:15135892 PMID:18571635 PMID:19345205 PMID:32092302 |
|
NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
|
|
G |
Bche |
butyrylcholinesterase |
decreases activity |
EXP ISO |
Rivastigmine results in decreased activity of BCHE protein |
CTD |
PMID:14535624 PMID:19345205 |
|
NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
|
|
G |
Ces1d |
carboxylesterase 1D |
decreases activity |
ISO |
Rivastigmine results in decreased activity of CES1 protein |
CTD |
PMID:23123248 |
|
NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
|
|
G |
Ces2h |
carboxylesterase 2H |
decreases activity |
ISO |
Rivastigmine results in decreased activity of CES2 protein |
CTD |
PMID:23123248 |
|
NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
|
|
G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions affects binding |
ISO |
Rivastigmine inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] Rivastigmine binds to [CHRNA4 protein binds to CHRNB2 protein] |
CTD |
PMID:15733544 |
|
NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
|
|
G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
affects binding multiple interactions |
ISO |
Rivastigmine binds to [CHRNA4 protein binds to CHRNB2 protein] Rivastigmine inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] |
CTD |
PMID:15733544 |
|
NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
|
|
G |
Hsf1 |
heat shock transcription factor 1 |
increases activity |
ISO |
Rivastigmine results in increased activity of HSF1 protein |
CTD |
PMID:19218096 |
|
NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
|
|
G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
ISO |
[Rivastigmine co-treated with donepezil] results in decreased expression of PTGS1 mRNA; [Rivastigmine co-treated with donepezil] results in decreased expression of PTGS1 protein; [Sodium Fluoride co-treated with Rivastigmine co-treated with donepezil] results in increased expression of PTGS1 mRNA; [Sodium Fluoride co-treated with Rivastigmine co-treated with donepezil] results in increased expression of PTGS1 protein; [Sodium Fluoride co-treated with Rivastigmine] results in increased expression of PTGS1 mRNA; [Sodium Fluoride co-treated with Rivastigmine] results in increased expression of PTGS1 protein |
CTD |
PMID:29777723 |
|
NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions decreases expression |
ISO |
[donepezil co-treated with Rivastigmine] results in decreased expression of PTGS2 protein; [Rivastigmine co-treated with donepezil] results in decreased expression of PTGS2 mRNA Rivastigmine results in decreased expression of PTGS2 mRNA; Rivastigmine results in decreased expression of PTGS2 protein |
CTD |
PMID:29777723 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
|
|