Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:risperidone
go back to main search page
Accession:CHEBI:8871 term browser browse the term
Definition:A member of the class of pyridopyrimidines that is 2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one carrying an additional 2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl group at position 2.
Synonyms:exact_synonym: 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
 related_synonym: Formula=C23H27FN4O2;   InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3;   InChIKey=RAPZEAPATHNIPO-UHFFFAOYSA-N;   Risperdal;   Risperin;   Rispolept;   Rispolin;   SMILES=Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12;   Sequinan;   risperidona;   risperidonum
 xref: Beilstein:4891881 "Beilstein";   CAS:106266-06-2 "ChemIDplus";   CAS:106266-06-2 "KEGG DRUG";   DrugBank:DB00734;   Drug_Central:2389 "DrugCentral";   HMDB:HMDB0005020;   KEGG:D00426;   LINCS:LSM-3193
 xref_mesh: MESH:D018967
 xref: PMID:11229618 "Europe PMC";   PMID:11476125 "Europe PMC";   PMID:14687852 "Europe PMC";   PMID:14728058 "Europe PMC";   PMID:15096074 "Europe PMC";   PMID:17054229 "Europe PMC";   PMID:18545060 "Europe PMC";   PMID:18722468 "Europe PMC";   PMID:19412457 "Europe PMC";   PMID:20825390 "Europe PMC";   PMID:23327578 "Europe PMC";   Patent:EP196132;   Patent:US4804663;   Reaxys:4891881 "Reaxys";   Wikipedia:Risperidone


show annotations for term's descendants       view all columns           Sort by:
 
risperidone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:6480464
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:6480464
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:6480464
G Camk4 calcium/calmodulin-dependent protein kinase IV JBrowse link 18 25,746,878 25,975,962 RGD:6480464
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 JBrowse link 10 59,585,023 59,608,180 RGD:6480464
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 JBrowse link 12 39,253,409 39,302,601 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:6480464
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:6480464
G Dvl3 dishevelled segment polarity protein 3 JBrowse link 11 84,051,177 84,068,479 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Egr2 early growth response 2 JBrowse link 20 22,452,170 22,461,018 RGD:6480464
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:6480464
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:6480464
G Fads2 fatty acid desaturase 2 JBrowse link 1 225,906,582 226,152,568 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:6480464
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Htr6 5-hydroxytryptamine receptor 6 JBrowse link 5 157,501,202 157,518,870 RGD:6480464
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480464
G Inha inhibin subunit alpha JBrowse link 9 82,700,482 82,703,383 RGD:6480464
G Inhbb inhibin subunit beta B JBrowse link 13 35,436,532 35,442,222 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6480464
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:6480464
G Maob monoamine oxidase B JBrowse link X 6,430,694 6,533,520 RGD:6480464
G Map2 microtubule-associated protein 2 JBrowse link 9 73,204,753 73,462,965 RGD:6480464
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Nrg1 neuregulin 1 JBrowse link 16 62,969,573 64,065,063 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:6480464
G S100b S100 calcium binding protein B JBrowse link 20 13,130,633 13,142,856 RGD:6480464
G Slc17a6 solute carrier family 17 member 6 JBrowse link 1 106,980,463 107,038,717 RGD:6480464
G Snap25 synaptosome associated protein 25 JBrowse link 3 129,697,408 129,788,417 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            central nervous system drug 16250
              psychotropic drug 14984
                risperidone 61
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  organic heteropolycyclic compound 17415
                                    organic heterobicyclic compound 15891
                                      benzoxazole 112
                                        benzisoxazole 71
                                          1,2-benzoxazoles 71
                                            risperidone 61
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.