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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:9E,11E-octadecadienoic acid
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Accession:CHEBI:88464 term browser browse the term
Definition:An octadeca-9,11-dienoic acid having 9-trans,11-trans-stereochemistry.
Synonyms:exact_synonym: (9E,11E)-octadeca-9,11-dienoic acid
 related_synonym: (9E,11E)-9,11-octadecadienoic acid;   (E,E)-9,11-octadecadienoic acid;   (E,E)-isolinoleic acid;   9-trans, 11-trans-CLA;   9-trans,11-trans-conjugated linoleic acid;   9E,11E-CLA;   9t,11t-CLA;   Formula=C18H32O2;   InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h7-10H,2-6,11-17H2,1H3,(H,19,20)/b8-7+,10-9+;   InChIKey=JBYXPOFIGCOSSB-XBLVEGMJSA-N;   Mangold's acid;   SMILES=OC(=O)CCCCCCC\\C=C\\C=C\\CCCCCC;   conjugated (9E,11E)-linoleic acid;   isolinoleic acid;   trans,trans-9,11-octadecadienoic acid
 xref: AGR:IND44166303;   CAS:544-71-8;   FooDB:FDB023609;   HMDB:HMDB0005047;   LIPID_MAPS_instance:LMFA01030119
 xref_mesh: MESH:C046938
 xref: PMID:11229917;   PMID:12619692;   PMID:16459922;   PMID:16477173;   PMID:17053429;   PMID:17217167;   PMID:17554969;   PMID:19443195;   PMID:19656856;   PMID:20016738;   PMID:2975566

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9E,11E-octadecadienoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule increases expression ISO 9,11-linoleic acid results in increased expression of CD36 mRNA CTD PMID:18155510 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Foxo1 forkhead box O1 affects localization ISO 9,11-linoleic acid affects the localization of FOXO1 protein CTD PMID:15992797 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO 9,11-linoleic acid binds to PPARA protein CTD PMID:23843199 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO 9,11-linoleic acid binds to PPARB protein CTD PMID:23843199 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
increases activity
ISO 9,11-linoleic acid binds to PPARG protein
9,11-linoleic acid results in increased activity of PPARG protein
CTD PMID:18155510 PMID:23843199 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO 9,11-linoleic acid results in increased phosphorylation of and affects the localization of TP53 protein CTD PMID:15992797 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      application 19494
        anti-inflammatory agent 14992
          9E,11E-octadecadienoic acid 6
            (9Z,11E)-9-hydroperoxyoctadeca-9,11-dienoic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic group 18569
                              organic divalent group 18560
                                organodiyl group 18560
                                  carbonyl group 18468
                                    carbonyl compound 18468
                                      carboxylic acid 18142
                                        monocarboxylic acid 17513
                                          fatty acid 16028
                                            unsaturated fatty acid 947
                                              polyunsaturated fatty acid 682
                                                octadecadienoic acid 160
                                                  conjugated linoleic acid 52
                                                    octadeca-9,11-dienoic acid 29
                                                      9E,11E-octadecadienoic acid 6
                                                        (9Z,11E)-9-hydroperoxyoctadeca-9,11-dienoic acid 0
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