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ONTOLOGY REPORT - ANNOTATIONS


Term:pyrrolotriazine
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Accession:CHEBI:88341 term browser browse the term
Definition:Any organic heterobicyclic compound containing ortho-fused pyrrolidine and triazine rings.
Synonyms:related_synonym: pyrrolotriazines


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BMS-754807 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:6480464
G Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:6480464
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:6480464
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    chemical entity 19660
      atom 19658
        nonmetal atom 19525
          nitrogen atom 18315
            nitrogen molecular entity 18315
              organonitrogen compound 18087
                organonitrogen heterocyclic compound 16979
                  pyrrolotriazine 8
                    4-\{[5-(methoxycarbamoyl)-2-methylphenyl]amino\}-5-methyl-N-[(1S)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 0
                    BMS-754807 8
                    N-(3-AMINOPROPYL)-N-[(R)-(3-BENZYL-5-CHLORO-4-OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL)(CYCLOPROPYL)METHYL]-4-METHYLBENZAMIDE 0
                    N-ethyl-4-\{[5-(methoxycarbamoyl)-2-methylphenyl]amino\}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      p-block molecular entity 19539
                        carbon group molecular entity 19422
                          organic molecular entity 19414
                            organic molecule 19337
                              organic cyclic compound 19089
                                organic heterocyclic compound 18164
                                  organic heteropolycyclic compound 17427
                                    organic heterobicyclic compound 15905
                                      pyrrolotriazine 8
                                        4-\{[5-(methoxycarbamoyl)-2-methylphenyl]amino\}-5-methyl-N-[(1S)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 0
                                        BMS-754807 8
                                        N-(3-AMINOPROPYL)-N-[(R)-(3-BENZYL-5-CHLORO-4-OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZIN-2-YL)(CYCLOPROPYL)METHYL]-4-METHYLBENZAMIDE 0
                                        N-ethyl-4-\{[5-(methoxycarbamoyl)-2-methylphenyl]amino\}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.