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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:88316 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
Synonyms:exact_synonym: rac-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine
 related_synonym: 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocin;   nefopamum
 xref: CAS:13669-70-0;   KEGG:D08258
 xref_mesh: MESH:D009340
 xref: PMID:23140663;   PMID:25534502;   PMID:25664155;   PMID:25855761;   PMID:25903742;   PMID:26047392;   PMID:26055978;   PMID:26240499;   PMID:26283884;   PMID:26475417;   Reaxys:1217383;   Wikipedia:Nefopam

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nefopam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Nefopam inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Nefopam inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein] CTD PMID:19096234 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      chemical substance 11959
        mixture 10880
          racemate 9777
            nefopam 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    main group molecular entity 19702
                      s-block molecular entity 19461
                        hydrogen molecular entity 19452
                          hydrides 18707
                            inorganic hydride 17430
                              pnictogen hydride 17402
                                nitrogen hydride 17243
                                  azane 16960
                                    ammonia 16959
                                      organic amino compound 16958
                                        tertiary amino compound 8643
                                          5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine 1
                                            (R)-nefopam 1
                                              nefopam 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.