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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:nefopam
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Accession:CHEBI:88316 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
Synonyms:exact_synonym: rac-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine
 related_synonym: 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocin;   nefopamum
 xref: CAS:13669-70-0;   KEGG:D08258
 xref_mesh: MESH:D009340
 xref: PMID:23140663;   PMID:25534502;   PMID:25664155;   PMID:25855761;   PMID:25903742;   PMID:26047392;   PMID:26055978;   PMID:26240499;   PMID:26283884;   PMID:26475417;   Reaxys:1217383;   Wikipedia:Nefopam


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nefopam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALCA calcitonin related polypeptide alpha multiple interactions ISO Nefopam inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Nefopam inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein] CTD PMID:19096234 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    chemical entity 26020
      chemical substance 15508
        mixture 14678
          racemate 12884
            nefopam 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    main group molecular entity 25841
                      s-block molecular entity 25162
                        hydrogen molecular entity 24761
                          hydrides 22973
                            inorganic hydride 20500
                              pnictogen hydride 20441
                                nitrogen hydride 20219
                                  azane 19961
                                    ammonia 19960
                                      organic amino compound 19960
                                        tertiary amino compound 10438
                                          5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine 1
                                            (R)-nefopam 1
                                              nefopam 1
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