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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nefopam
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Accession:CHEBI:88316 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
Synonyms:exact_synonym: rac-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine
 related_synonym: 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocin;   nefopamum
 xref: CAS:13669-70-0;   KEGG:D08258
 xref_mesh: MESH:D009340
 xref: PMID:23140663;   PMID:25534502;   PMID:25664155;   PMID:25855761;   PMID:25903742;   PMID:26047392;   PMID:26055978;   PMID:26240499;   PMID:26283884;   PMID:26475417;   Reaxys:1217383;   Wikipedia:Nefopam


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nefopam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Nefopam inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Nefopam inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein] CTD PMID:19096234 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      chemical substance 11928
        mixture 10845
          racemate 9741
            nefopam 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            inorganic hydride 17411
                              pnictogen hydride 17383
                                nitrogen hydride 17224
                                  azane 16941
                                    ammonia 16940
                                      organic amino compound 16939
                                        tertiary amino compound 8630
                                          5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine 1
                                            (R)-nefopam 1
                                              nefopam 1
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