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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nefopam
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Accession:CHEBI:88316 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-nefopam. The hydrochloride is a centrally acting non-opiate analgesic commonly used for the treatment of moderate to severe pain.
Synonyms:exact_synonym: rac-5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine
 related_synonym: 3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocin;   nefopamum
 xref: CAS:13669-70-0;   KEGG:D08258
 xref_mesh: MESH:D009340
 xref: PMID:23140663;   PMID:25534502;   PMID:25664155;   PMID:25855761;   PMID:25903742;   PMID:26047392;   PMID:26055978;   PMID:26240499;   PMID:26283884;   PMID:26475417;   Reaxys:1217383;   Wikipedia:Nefopam



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nefopam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Nefopam inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]; Nefopam inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein] CTD PMID:19096234 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      chemical substance 13190
        mixture 12396
          racemate 10478
            nefopam 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    main group molecular entity 19698
                      s-block molecular entity 19479
                        hydrogen molecular entity 19471
                          hydrides 18834
                            inorganic hydride 17691
                              pnictogen hydride 17671
                                nitrogen hydride 17543
                                  azane 17278
                                    ammonia 17277
                                      organic amino compound 17277
                                        tertiary amino compound 8697
                                          5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-benzoxazocine 1
                                            (R)-nefopam 1
                                              nefopam 1
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