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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:azaperone
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Accession:CHEBI:88301 term browser browse the term
Definition:An N-arylpiperazine that is 2-(piperazin-1-yl)pyridine in which the amino hydrogen is replaced by a 3-(4-fluobenzoyl)propyl group. Used mainly as a tranquiliser for pigs and elephants.
Synonyms:exact_synonym: 1-(4-fluorophenyl)-4-[4-(pyridin-2-yl)piperazin-1-yl]butan-1-one
 related_synonym: 1-(3-(4-Fluorobenzoyl)propyl)-4-(2-pyridyl)piperazine;   1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1-butanone;   4'-Fluoro-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone;   Azaperon;   Formula=C19H22FN3O;   InChI=1S/C19H22FN3O/c20-17-8-6-16(7-9-17)18(24)4-3-11-22-12-14-23(15-13-22)19-5-1-2-10-21-19/h1-2,5-10H,3-4,11-15H2;   InChIKey=XTKDAFGWCDAMPY-UHFFFAOYSA-N;   NSC 170976;   SMILES=C1=C(C=CC(=C1)C(CCCN2CCN(CC2)C3=CC=CC=N3)=O)F;   Stresnil;   azaperona;   azaperonum
 xref: CAS:1649-18-9;   KEGG:D02620;   LINCS:LSM-3012
 xref_mesh: MESH:D001376
 xref: PMID:10982132;   PMID:12398308;   PMID:17186408;   PMID:17386737;   PMID:17929705;   PMID:17939346;   PMID:18689666;   PMID:18817017;   PMID:19111512;   PMID:19395755;   PMID:19395756;   PMID:19579764;   PMID:20006891;   PMID:21210371;   PMID:22287670;   PMID:23140663;   PMID:24490337;   PMID:24712163;   PMID:24807358;   PMID:25105814;   PMID:25655411;   PMID:26056882;   Reaxys:565491;   VSDB:1871;   Wikipedia:Azaperone



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azaperone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Azaperone results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:11,719,357...11,751,424 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19898
    role 19869
      biological role 19867
        pharmacological role 19102
          antagonist 17260
            dopaminergic antagonist 1641
              azaperone 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    main group molecular entity 19835
                      s-block molecular entity 19670
                        hydrogen molecular entity 19652
                          hydrides 19164
                            inorganic hydride 18180
                              pnictogen hydride 18170
                                nitrogen hydride 18083
                                  azane 17892
                                    ammonia 17891
                                      organic amino compound 17891
                                        aromatic amine 15504
                                          aminopyridine 516
                                            azaperone 1
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