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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:G-protein-coupled receptor antagonist
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Accession:CHEBI:88295 term browser browse the term
Definition:An antagonist at G-protein-coupled receptor.
Synonyms:related_synonym: G-protein-coupled receptor antagonists;   GPCR antagonist;   GPCR antagonists
 xref: Wikipedia:G_protein-coupled_receptor


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gallein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased phosphorylation of AKT1 protein] CTD PMID:35901927 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]] CTD PMID:35901927 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased expression of BCL2 protein] CTD PMID:35901927 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased expression of BCL2L1 protein] CTD PMID:35901927 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Cat catalase multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased expression of CAT protein] CTD PMID:35901927 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased expression of GPX1 protein] CTD PMID:35901927 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased phosphorylation of MAPK1 protein] CTD PMID:35901927 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased phosphorylation of MAPK3 protein] CTD PMID:35901927 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP gallein inhibits the reaction [Chloroquine affects the localization of SLC2A4 protein] CTD PMID:27160165 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        pharmacological role 19911
          antagonist 17594
            G-protein-coupled receptor antagonist 9
              C3a receptor antagonist 0
              C5a receptor antagonist + 0
              G-15 0
              P2Y14 receptor antagonist + 0
              [(3S,4R,8R,9E)-10-methyl-5-methylidene-6,14-dioxo-7,13-dioxatricyclo[10.2.1.04,8]pentadeca-1(15),9-dien-3-yl] (Z)-2-methylbut-2-enoate 0
              calcitonin gene-related peptide receptor antagonist + 0
              gallein 9
              protease-activated receptor-1 antagonist + 0
              protease-activated receptor-2 antagonist + 0
paths to the root