Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Community Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gallein
go back to main search page
Accession:CHEBI:88294 term browser browse the term
Definition:A xanthene dye that is fluoran carrying four hydroxy substituents at positions 3', 4', 5' and 6'.
Synonyms:exact_synonym: 3',4',5',6'-tetrahydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
 related_synonym: 3',4',5',6'-Tetrahydroxyfluoran;   3',4',5',6'-Tetrahydroxyspiro(isobenzofuran-1(3H),9'-(9H)xanthene)-3-one;   4,5-Dihydroxyfluorescein;   Alizarin violet;   C.I. 45445;   C.I. Mordant Violet 25;   Formula=C20H12O7;   InChI=1S/C20H12O7/c21-13-7-5-11-17(15(13)23)26-18-12(6-8-14(22)16(18)24)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,21-24H;   InChIKey=PHLYOKFVXIVOJC-UHFFFAOYSA-N;   Mordant violet 25;   Pyrogallolphthalein;   SMILES=OC1=CC=C2C3(OC(C4=C3C=CC=C4)=O)C=5C(OC2=C1O)=C(C(=CC5)O)O
 xref: CAS:2103-64-2
 xref_mesh: MESH:C007820
 xref: PMID:25629163;   PMID:25759388;   PMID:25941381;   Reaxys:58028


show annotations for term's descendants           Sort by:
gallein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased phosphorylation of AKT1 protein] CTD PMID:35901927 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]] CTD PMID:35901927 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased expression of BCL2 protein] CTD PMID:35901927 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased expression of BCL2L1 protein] CTD PMID:35901927 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Cat catalase multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased expression of CAT protein] CTD PMID:35901927 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased expression of GPX1 protein] CTD PMID:35901927 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased phosphorylation of MAPK1 protein] CTD PMID:35901927 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP gallein inhibits the reaction [N(6)-cyclopentyladenosine results in increased phosphorylation of MAPK3 protein] CTD PMID:35901927 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP gallein inhibits the reaction [Chloroquine affects the localization of SLC2A4 protein] CTD PMID:27160165 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19876
    role 19851
      application 19687
        dye 2963
          xanthene dye 88
            gallein 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19876
    subatomic particle 19874
      composite particle 19874
        hadron 19874
          baryon 19874
            nucleon 19874
              atomic nucleus 19905
                atom 19905
                  main group element atom 19821
                    p-block element atom 19821
                      carbon group element atom 19768
                        carbon atom 19764
                          organic molecular entity 19764
                            organic group 18962
                              organic divalent group 18943
                                organodiyl group 18915
                                  carbonyl group 18869
                                    carbonyl compound 18869
                                      carboxylic ester 16114
                                        lactone 11519
                                          gamma-lactone 6844
                                            gallein 9
paths to the root