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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:rhodamine 123
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Accession:CHEBI:8828 term browser browse the term
Definition:A xanthene dye that has formula C21H17ClN2O3.
Synonyms:exact_synonym: 6-amino-9-[2-(methoxycarbonyl)phenyl]-3H-xanthen-3-iminium chloride
 related_synonym: Formula=C21H17ClN2O3;   InChI=1S/C21H16N2O3.ClH/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20;/h2-11,22H,23H2,1H3;1H;   InChIKey=MYFATKRONKHHQL-UHFFFAOYSA-N;   RH 123;   SMILES=[Cl-].COC(=O)c1ccccc1-c1c2ccc(N)cc2oc2cc(=[NH2+])ccc12;   rhodamine 110 methyl ester
 xref: Beilstein:6030951;   CAS:62669-70-9;   KEGG:C11190
 xref_mesh: MESH:D020112



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rhodamine 123 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases uptake
increases export
ISO
EXP
3-methylquercetin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; 3-methylquercetin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; 5,7-dimethoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; 5,7-dimethoxyflavone inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; 5-hydroxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; 5-methoxyflavone inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; 5-oxo-hexahydroquinoline analog inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; abemaciclib inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; baicalein inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; baicalein promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; betulin inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; biochanin A inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; biochanin A promotes the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; CEP 33779 inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]; daidzein inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; flavone inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; formononetin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; Genistein promotes the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; glycitein promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; isovitexin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; kaempferol inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; myricetin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; naringenin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; naringin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; Quercetin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; Quercetin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; quercitrin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; Rutin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; tangeretin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; tangeretin inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; taxifolin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; Verapamil inhibits the reaction [ABCB1 protein results in increased export of Rhodamine 123]
[P-glycoprotein inducer and activator TX5 results in increased activity of ABCB1 protein] which results in increased export of Rhodamine 123; [Verapamil results in decreased activity of ABCB1 protein] inhibits the reaction [P-glycoprotein inducer and activator TX5 results in increased export of Rhodamine 123]
CTD PMID:25058526 PMID:27816545 PMID:30391378 PMID:31756430 PMID:33321149 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases export
ISO abemaciclib inhibits the reaction [ABCG2 protein results in increased export of Rhodamine 123] CTD PMID:27816545 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        dye 1366
          xanthene dye 80
            rhodamine 123 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic heterocyclic compound 18824
                                  oxacycle 17688
                                    dibenzopyran 243
                                      xanthenes 237
                                        xanthene dye 80
                                          rhodamine 123(1+) 2
                                            rhodamine 123 2
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