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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine
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Accession:CHEBI:88217 term browser browse the term
Definition:An N-substituted diamine that is ethylenediamine in which the four amino hydrogens are replaced by 2-pyridylmethyl groups.
Synonyms:exact_synonym: N(1),N(1),N(2),N(2)-tetrakis[(pyridin-2-yl)methyl]ethane-1,2-diamine
 related_synonym: Formula=C26H28N6;   InChI=1S/C26H28N6/c1-5-13-27-23(9-1)19-31(20-24-10-2-6-14-28-24)17-18-32(21-25-11-3-7-15-29-25)22-26-12-4-8-16-30-26/h1-16H,17-22H2;   InChIKey=CVRXLMUYFMERMJ-UHFFFAOYSA-N;   SMILES=C(CN(CC1=NC=CC=C1)CC2=NC=CC=C2)N(CC3=NC=CC=C3)CC4=NC=CC=C4;   TPEN
 xref: CAS:16858-02-9;   LINCS:LSM-19976
 xref_mesh: MESH:C044387
 xref: PMID:22225878;   PMID:25667569;   PMID:25813624;   PMID:25973665;   PMID:26004891;   PMID:26143360;   PMID:26190227;   Reaxys:4211982


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N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of AARS1 mRNA CTD PMID:19013360 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ABCC10 mRNA CTD PMID:12756304 NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of ABCC9 mRNA CTD PMID:12756304 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ABL1 mRNA CTD PMID:12756304 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain decreases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ACADL protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ACADL protein]
CTD PMID:19637192 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Agt angiotensinogen multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in decreased expression of CAT protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in increased localization of Zinc] CTD PMID:22427991 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] affects the localization of AIFM1 protein] CTD PMID:18951928 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of ALPL mRNA CTD PMID:19913120 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of AP2B1 mRNA CTD PMID:12756304 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of APC2 mRNA CTD PMID:12756304 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
JBrowse link
G Apob apolipoprotein B decreases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of APOB protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of APOB protein]
CTD PMID:19637192 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Arhgef18 Rho/Rac guanine nucleotide exchange factor 18 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ARHGEF18 mRNA CTD PMID:12756304 NCBI chr12:1,395,035...1,503,081
Ensembl chr12:1,395,088...1,503,081
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of ATM mRNA CTD PMID:33645215 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Azin1 antizyme inhibitor 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of AZIN1 mRNA CTD PMID:12756304 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]] CTD PMID:19887557 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BBC3 mRNA CTD PMID:12756304 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bbs9 Bardet-Biedl syndrome 9 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of BBS9 mRNA CTD PMID:12756304 NCBI chr 8:21,013,865...21,437,934
Ensembl chr 8:21,013,944...21,437,930
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BCL2 mRNA
CTD PMID:19887557 PMID:33645215 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]] CTD PMID:19887557 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of BGLAP protein
[zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of BGLAP mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of BGLAP mRNA
CTD PMID:19913120 PMID:22228435 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of BRCA2 mRNA CTD PMID:33645215 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brd1 bromodomain containing 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BRD1 mRNA CTD PMID:12756304 NCBI chr 7:119,774,187...119,822,031
Ensembl chr 7:119,774,188...119,822,031
JBrowse link
G Brd3 bromodomain containing 3 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BRD3 mRNA CTD PMID:12756304 NCBI chr 3:10,773,163...10,829,675
Ensembl chr 3:10,775,272...10,829,577
JBrowse link
G Brd8 bromodomain containing 8 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of BRD8 mRNA CTD PMID:12756304 NCBI chr18:26,181,744...26,230,035
Ensembl chr18:26,181,732...26,229,884
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions ISO 3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of CACNA1H protein CTD PMID:29129814 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Camsap1 calmodulin regulated spectrin-associated protein 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CAMSAP1 mRNA CTD PMID:12756304 NCBI chr 3:8,746,176...8,806,072
Ensembl chr 3:8,746,176...8,806,072
JBrowse link
G Casp1 caspase 1 increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CASP1 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased activity of CASP1 protein]
CTD PMID:17622302 PMID:19130485 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
decreases expression
ISO [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased activity of CASP3 protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CASP3 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP3 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CASP3 mRNA
CTD PMID:15966574 PMID:16844947 PMID:17169355 PMID:17979179 PMID:18778698 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP8 protein CTD PMID:17979179 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of CASP9 protein CTD PMID:17169355 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
increases expression
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [AGT protein results in decreased expression of CAT protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CAT protein
CTD PMID:22427991 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCL2 mRNA CTD PMID:19013360 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCL22 mRNA CTD PMID:19013360 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCL3 mRNA CTD PMID:19013360 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCND1 mRNA CTD PMID:12756304 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCR1 mRNA CTD PMID:19013360 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CCR2 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CCR2 mRNA
CTD PMID:12756304 PMID:19013360 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd14 CD14 molecule multiple interactions
increases expression
ISO [Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD14 protein]; parthenolide promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]; pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of CD14 protein]]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CD14 protein
CTD PMID:20089671 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd86 CD86 molecule increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CD86 protein CTD PMID:16892068 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein] CTD PMID:16844947 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CDKN1A mRNA CTD PMID:33645215 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CEBPD mRNA CTD PMID:12756304 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cfp complement factor properdin increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CFP mRNA CTD PMID:19013360 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573
JBrowse link
G Clcn7 chloride voltage-gated channel 7 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CLCN7 mRNA CTD PMID:12756304 NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130
JBrowse link
G Clcnkb chloride voltage-gated channel Kb increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CLCNKB mRNA CTD PMID:12756304 NCBI chr 5:153,710,086...153,733,162
Ensembl chr 5:153,710,094...153,732,153
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of COL1A1 mRNA CTD PMID:19913120 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Crebbp CREB binding protein multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [HIF1A protein binds to CREBBP protein] CTD PMID:16579968 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Cryz crystallin zeta decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CRYZ mRNA CTD PMID:12888634 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CTDP1 mRNA CTD PMID:12756304 NCBI chr18:73,854,277...73,916,232
Ensembl chr18:73,854,282...73,916,457
JBrowse link
G Ctdsp2 CTD small phosphatase 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CTDSP2 mRNA CTD PMID:12756304 NCBI chr 7:62,805,400...62,825,306 JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein] CTD PMID:16844947 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsd cathepsin D multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Ethambutol results in increased expression of and affects the localization of CTSD protein] CTD PMID:19063910 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsk cathepsin K increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CTSK mRNA CTD PMID:19013360 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CX3CR1 mRNA CTD PMID:19013360 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of CXCL2 mRNA CTD PMID:19013360 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyth4 cytohesin 4 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CYTH4 mRNA CTD PMID:12756304 NCBI chr 7:110,152,232...110,176,741
Ensembl chr 7:110,152,272...110,176,741
JBrowse link
G Dad1 defender against cell death 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DAD1 mRNA CTD PMID:12888634 NCBI chr15:27,677,285...27,697,275
Ensembl chr15:27,677,268...27,697,347
JBrowse link
G Ddx23 DEAD-box helicase 23 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DDX23 mRNA CTD PMID:12756304 NCBI chr 7:129,797,620...129,814,909
Ensembl chr 7:129,797,614...129,814,949
JBrowse link
G Dgcr2 DiGeorge syndrome critical region gene 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DGCR2 mRNA CTD PMID:12756304 NCBI chr11:83,093,961...83,144,507
Ensembl chr11:83,094,037...83,144,502
JBrowse link
G Dgkz diacylglycerol kinase zeta decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DGKZ mRNA CTD PMID:12756304 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Dhx58 DEXH-box helicase 58 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of DHX58 mRNA CTD PMID:12756304 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DICER1 mRNA CTD PMID:12756304 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dspp dentin sialophosphoprotein multiple interactions
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [NFIC protein binds to DSPP promoter]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of DSPP mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of DSPP protein
CTD PMID:22228435 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
JBrowse link
G Dstn destrin, actin depolymerizing factor increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of DSTN mRNA CTD PMID:12756304 NCBI chr 3:131,284,647...131,311,361
Ensembl chr 3:131,284,648...131,311,379
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of DYNC1LI2 mRNA CTD PMID:12756304 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of E2F1 mRNA CTD PMID:33645215 NCBI chr 3:143,064,535...143,075,362 JBrowse link
G Eef1akmt2 EEF1A lysine methyltransferase 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of EEF1AKMT2 mRNA CTD PMID:19013360 NCBI chr 1:187,616,156...187,640,937
Ensembl chr 1:187,500,744...187,640,937
JBrowse link
G Egfl7 EGF-like-domain, multiple 7 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of EGFL7 mRNA CTD PMID:12756304 NCBI chr 3:9,404,622...9,416,879
Ensembl chr 3:9,407,520...9,416,879
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 increases activity
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein
zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of EGLN1 protein]
CTD PMID:16579968 PMID:16973622 NCBI chr19:52,867,914...52,907,169 JBrowse link
G Egr1 early growth response 1 multiple interactions ISO 3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of EGR1 protein CTD PMID:29129814 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ehd1 EH-domain containing 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of EHD1 mRNA CTD PMID:12756304 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212
JBrowse link
G Elf4 E74 like ETS transcription factor 4 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ELF4 mRNA CTD PMID:12756304 NCBI chr  X:127,587,401...127,639,063
Ensembl chr  X:127,590,650...127,630,200
JBrowse link
G Ess2 ess-2 splicing factor homolog decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ESS2 mRNA CTD PMID:12756304 NCBI chr11:83,075,893...83,085,849
Ensembl chr11:83,075,925...83,084,846
JBrowse link
G Fadd Fas associated via death domain decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of FADD mRNA CTD PMID:12756304 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fam13a family with sequence similarity 13, member A increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of FAM13A mRNA CTD PMID:12756304 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of PRKCB protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of IL6 mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of IL6 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of TNF mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of TNF protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased phosphorylation of IKBKB protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]] CTD PMID:16818790 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of FEZ1 mRNA CTD PMID:12756304 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased expression of FOS mRNA] CTD PMID:20201035 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxo3 forkhead box O3 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of FOXO3 mRNA CTD PMID:12756304 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Frat2 FRAT regulator of WNT signaling pathway 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of FRAT2 mRNA CTD PMID:12756304 NCBI chr 1:240,654,120...240,656,685
Ensembl chr 1:240,654,137...240,656,517
JBrowse link
G Fzr1 fizzy and cell division cycle 20 related 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of FZR1 mRNA CTD PMID:12756304 NCBI chr 7:8,332,029...8,343,953
Ensembl chr 7:8,332,029...8,343,952
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of G6PD mRNA CTD PMID:12888634 PMID:17018880 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of GADD45A mRNA CTD PMID:33645215 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gata1 GATA binding protein 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [GATA1 protein binds to ZFPM1 protein] CTD PMID:33149232 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gga2 golgi associated, gamma adaptin ear containing, ARF binding protein 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GGA2 mRNA CTD PMID:12756304 NCBI chr 1:176,552,046...176,585,332
Ensembl chr 1:176,552,046...176,585,361
JBrowse link
G Gmip Gem-interacting protein decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GMIP mRNA CTD PMID:12756304 NCBI chr16:19,600,723...19,614,459
Ensembl chr16:19,600,723...19,614,027
JBrowse link
G Golph3l golgi phosphoprotein 3-like decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GOLPH3L mRNA CTD PMID:12756304 NCBI chr 2:183,151,941...183,183,094
Ensembl chr 2:183,153,301...183,183,083
JBrowse link
G Gorasp2 golgi reassembly stacking protein 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GORASP2 mRNA CTD PMID:12756304 NCBI chr 3:55,474,448...55,503,570
Ensembl chr 3:55,474,757...55,503,576
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of GSTA1 mRNA CTD PMID:17018880 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H1-2 mRNA CTD PMID:19013360 NCBI chr17:41,391,106...41,392,611 JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC12 mRNA CTD PMID:19013360 NCBI chr17:42,485,746...42,486,126 JBrowse link
G H2bc9 H2B clustered histone 9 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC9 mRNA CTD PMID:19013360 NCBI chr17:42,470,593...42,478,605 JBrowse link
G H4f3 H1.3 linker histone, cluster member increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H1-3 mRNA CTD PMID:19013360 NCBI chr17:41,528,576...41,554,586
Ensembl chr17:41,529,667...41,552,334
JBrowse link
G Hax1 HCLS1 associated protein X-1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of HAX1 mRNA CTD PMID:17622302 NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714
JBrowse link
G Hic2 HIC ZBTB transcriptional repressor 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of HIC2 mRNA CTD PMID:12756304 NCBI chr11:83,737,075...83,789,554
Ensembl chr11:83,738,874...83,767,484
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [HIF1A protein binds to CREBBP protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased ubiquitination of and results in increased expression of HIF1A protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased stability of and results in increased expression of HIF1A protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of HIF1A protein
CTD PMID:16579968 PMID:16973622 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2BC5 mRNA CTD PMID:19013360 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H2AC18 mRNA CTD PMID:19013360 NCBI chr 2:183,808,398...183,808,922 JBrowse link
G Hlx H2.0-like homeobox decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of HLX mRNA CTD PMID:12756304 NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
JBrowse link
G Hmox2 heme oxygenase 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of HMOX2 mRNA CTD PMID:12888634 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases activity
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of HNF4A protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of HNF4A protein]
CTD PMID:19637192 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnmt histamine N-methyltransferase increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of HNMT mRNA CTD PMID:12756304 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IFI27 mRNA CTD PMID:12756304 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
JBrowse link
G Ifng interferon gamma multiple interactions ISO [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased activity of CASP3 protein; [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein; [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased secretion of IFNG protein]; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein]; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein] CTD PMID:16844947 PMID:17150331 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IFNGR1 mRNA CTD PMID:19013360 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Ifngr2 interferon gamma receptor 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IFNGR2 mRNA CTD PMID:12756304 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:14644152 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein] CTD PMID:14644152 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased phosphorylation of IKBKB protein] CTD PMID:16818790 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in decreased secretion of IL10 protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IL10 mRNA
CTD PMID:17150331 PMID:19013360 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL10RA mRNA CTD PMID:19013360 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Il10rb interleukin 10 receptor subunit beta increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL10RB mRNA CTD PMID:19013360 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL13RA1 mRNA CTD PMID:19013360 NCBI chr  X:115,348,860...115,408,682
Ensembl chr  X:115,348,860...115,408,681
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL1B mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased cleavage of IL1B protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Nigericin] results in increased secretion of IL1B protein]; zinc chloride inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]]
CTD PMID:17622302 PMID:19130485 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased expression of FOS mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [IL2 protein results in increased phosphorylation of STAT5A protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [IL2 protein results in increased phosphorylation of STAT5B protein] CTD PMID:20201035 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IL4 mRNA CTD PMID:19013360 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il4r interleukin 4 receptor decreases expression
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IL4R mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL4R mRNA
CTD PMID:12756304 PMID:19013360 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased secretion of IL6 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of IL6 mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of IL6 protein]
CTD PMID:16818790 PMID:18615482 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IL6R mRNA CTD PMID:19013360 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Ints6 integrator complex subunit 6 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of INTS6 mRNA CTD PMID:12756304 NCBI chr15:36,908,966...37,048,043
Ensembl chr15:36,933,724...37,021,527
JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of IQGAP2 mRNA CTD PMID:19013360 NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279
JBrowse link
G Irf1 interferon regulatory factor 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of IRF1 mRNA CTD PMID:12756304 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of ISG15 mRNA CTD PMID:19013360 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [Zinc co-treated with pyrithione] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]; parthenolide promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]]; pyrithione promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Calcitriol results in increased expression of ITGAM protein]] CTD PMID:20089671 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itsn2 intersectin 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ITSN2 mRNA CTD PMID:12756304 NCBI chr 6:27,616,645...27,727,373
Ensembl chr 6:27,600,406...27,727,124
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased activity of JUN protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc Sulfate results in increased activity of JUN protein] CTD PMID:16606632 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kat6a lysine acetyltransferase 6A decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of KAT6A mRNA CTD PMID:12756304 NCBI chr16:69,084,914...69,165,923
Ensembl chr16:69,084,914...69,163,606
JBrowse link
G Kazn kazrin, periplakin interacting protein decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of KAZN mRNA CTD PMID:12756304 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [dexamethasone 21-methanesulfonate binds to KEAP1 protein] CTD PMID:15865434 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of KIF23 mRNA CTD PMID:12888634 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Krt8 keratin 8 increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA]
CTD PMID:18778698 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 decreases expression
multiple interactions
ISO
EXP
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LAMP2 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Ethambutol results in increased expression of LAMP2 protein]
CTD PMID:12888634 PMID:19063910 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lats2 large tumor suppressor kinase 2 decreases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LATS2 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LATS2 mRNA]
CTD PMID:18778698 NCBI chr15:31,825,068...31,877,193
Ensembl chr15:31,825,092...31,877,220
JBrowse link
G Lig3 DNA ligase 3 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of LIG3 mRNA CTD PMID:33645215 NCBI chr10:67,717,796...67,741,141
Ensembl chr10:67,717,812...67,798,414
JBrowse link
G Lilra5 leukocyte immunoglobulin like receptor A5 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of LILRA5 mRNA CTD PMID:19013360 NCBI chr 1:69,973,292...69,978,750
Ensembl chr 1:69,973,292...70,001,718
JBrowse link
G LOC684819 similar to H3 histone, family 2 isoform 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of H3C11 mRNA CTD PMID:19013360
G Lta lymphotoxin alpha increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of LTA mRNA CTD PMID:12888634 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
JBrowse link
G Mad2l1bp MAD2L1 binding protein decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MAD2L1BP mRNA CTD PMID:12756304 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MAP2K5 mRNA CTD PMID:12888634 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:11331359 PMID:20201035 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:20201035 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MAPKBP1 mRNA CTD PMID:12756304 NCBI chr 3:106,947,342...106,998,368
Ensembl chr 3:106,947,827...106,996,199
JBrowse link
G Mbnl2 muscleblind-like splicing regulator 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MBNL2 mRNA CTD PMID:12756304 NCBI chr15:97,385,238...97,542,924
Ensembl chr15:97,385,244...97,542,937
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MDM2 mRNA CTD PMID:33645215 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MMP10 mRNA CTD PMID:12888634 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glutathione binds to MMP9 protein] CTD PMID:17015178 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mrpl12 mitochondrial ribosomal protein L12 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MRPL12 mRNA CTD PMID:19013360 NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO
EXP
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in increased expression of MT1 mRNA]
[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc co-treated with ochratoxin A] results in increased expression of MT1A mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of MT1A mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT1A mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of MT1A mRNA]
CTD PMID:14617770 PMID:17018880 PMID:19720134 PMID:23056475 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO
EXP
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene results in increased expression of MT2 mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of MT2A mRNA]
[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc co-treated with ochratoxin A] results in increased expression of MT2A mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of MT2A mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nickel results in increased expression of MT2A mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT2A mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased expression of MT2A mRNA]
CTD PMID:14617770 PMID:17018880 PMID:19097988 PMID:19720134 PMID:23056475 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MTF1 mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [MTF1 protein binds to SLC39A10 promoter]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MTF1 mRNA
CTD PMID:12756304 PMID:12888634 PMID:17018880 PMID:21738690 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MTTP protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MTTP protein]
CTD PMID:19637192 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Mtx1 Metaxin 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MTX1 mRNA CTD PMID:33645215 NCBI chr 2:174,615,460...174,621,383
Ensembl chr 2:174,615,461...174,620,982
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of MYC mRNA CTD PMID:19013360 PMID:33645215 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MYD88 mRNA CTD PMID:17622302 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nab2 Ngfi-A binding protein 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NAB2 mRNA CTD PMID:12756304 NCBI chr 7:63,497,589...63,504,105
Ensembl chr 7:63,497,589...63,503,989
JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of NCBP2 mRNA CTD PMID:12756304 NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885
JBrowse link
G Ncln nicalin decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NCLN mRNA CTD PMID:12756304 NCBI chr 7:8,211,978...8,221,938
Ensembl chr 7:8,211,996...8,221,934
JBrowse link
G Nfic nuclear factor I/C multiple interactions
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [NFIC protein binds to DSPP promoter]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of NFIC protein
CTD PMID:22228435 NCBI chr 7:8,278,210...8,309,936
Ensembl chr 7:8,253,361...8,309,936
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
affects localization
ISO Copper inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the localization of NFKB1 protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the localization of NFKB1 protein] CTD PMID:18615482 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases degradation
decreases expression
ISO Copper inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased degradation of NFKBIA protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased degradation of NFKBIA protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NFKBIA mRNA
CTD PMID:12756304 PMID:18615482 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nkx3-2 NK3 homeobox 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NKX3-2 mRNA CTD PMID:12756304 NCBI chr14:69,183,795...69,186,182
Ensembl chr14:69,183,820...69,186,061
JBrowse link
G Nlgn1 neuroligin 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of NLGN1 mRNA CTD PMID:12756304 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464
JBrowse link
G Nlrx1 NLR family member X1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NLRX1 mRNA CTD PMID:12756304 NCBI chr 8:44,588,476...44,606,678
Ensembl chr 8:44,590,048...44,606,484
JBrowse link
G Nsmce4a NSE4 homolog A, SMC5-SMC6 complex component decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of NSMCE4A mRNA CTD PMID:12756304 NCBI chr 1:185,102,075...185,109,166
Ensembl chr 1:185,094,360...185,109,166
JBrowse link
G Nup50 nucleoporin 50 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of NUP50 mRNA CTD PMID:12756304 NCBI chr 7:116,047,960...116,065,231
Ensembl chr 7:116,048,021...116,066,905
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of OGT mRNA CTD PMID:12756304 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FK 409 promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FK 409 promotes the reaction [OPRM1 protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to RAF1 protein]] CTD PMID:18652891 PMID:21235400 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
decreases activity
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [zinc chloride results in increased expression of PARP1 protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of PARP1 protein
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc binds to PARP1 protein]
CTD PMID:15966574 PMID:22253048 PMID:24275069 PMID:33645215 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of PIK3C3 mRNA CTD PMID:12756304 NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PLSCR1 mRNA CTD PMID:12756304 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Polb DNA polymerase beta increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of POLB mRNA CTD PMID:33645215 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Polr2a RNA polymerase II subunit A decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of POLR2A mRNA CTD PMID:12756304 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
JBrowse link
G Polr2d RNA polymerase II subunit D decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of POLR2D mRNA CTD PMID:12756304 NCBI chr18:23,418,097...23,425,228
Ensembl chr18:23,418,097...23,425,228
JBrowse link
G Pon2 paraoxonase 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of PON2 mRNA CTD PMID:12888634 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
JBrowse link
G Pou4f2 POU class 4 homeobox 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of POU4F2 mRNA CTD PMID:12756304 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases activity
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of PPARA protein
Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased activity of PPARA protein]
CTD PMID:19637192 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppp2r2d protein phosphatase 2, regulatory subunit B, delta decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of PPP2R2D mRNA CTD PMID:12756304 NCBI chr 1:193,665,918...193,700,277
Ensembl chr 1:193,665,855...193,700,274
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of PRKCB protein] CTD PMID:16818790 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FK 409 promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 PMID:21235400 NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
JBrowse link
G Psmb2 proteasome 20S subunit beta 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PSMB2 mRNA CTD PMID:12756304 NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137
JBrowse link
G Ptcra pre T-cell antigen receptor alpha increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PTCRA mRNA CTD PMID:19013360 NCBI chr 9:14,218,366...14,229,141
Ensembl chr 9:14,218,802...14,229,235
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of PTH1R mRNA CTD PMID:19913120 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PTP4A1 mRNA CTD PMID:12756304 NCBI chr 9:33,214,201...33,245,046
Ensembl chr 9:33,214,208...33,221,964
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of PTPRN mRNA CTD PMID:17622302 PMID:19013360 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
JBrowse link
G Pus1 pseudouridine synthase 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of PUS1 mRNA CTD PMID:12756304 NCBI chr12:45,880,364...45,889,196
Ensembl chr12:45,880,440...45,889,196
JBrowse link
G Qrich1 glutamine-rich 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of QRICH1 mRNA CTD PMID:12756304 NCBI chr 8:109,216,900...109,256,472
Ensembl chr 8:109,217,376...109,261,359
JBrowse link
G Rad51 RAD51 recombinase increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RAD51 mRNA CTD PMID:12888634 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad51c RAD51 paralog C increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RAD51C mRNA CTD PMID:12756304 NCBI chr10:72,205,032...72,231,643
Ensembl chr10:72,205,032...72,231,248
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FK 409 promotes the reaction [OPRM1 protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein binds to RAF1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to RAF1 protein]] CTD PMID:21235400 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rb1 RB transcriptional corepressor 1 increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA]
CTD PMID:18778698 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in decreased activity of RELA protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc Sulfate results in decreased activity of RELA protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein affects the localization of RELA protein]]
CTD PMID:16606632 PMID:16818790 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Repin1 replication initiator 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of REPIN1 mRNA CTD PMID:12756304 NCBI chr 4:77,548,722...77,554,242
Ensembl chr 4:77,548,849...77,554,257
JBrowse link
G RGD1564804 similar to chromosome 1 open reading frame 50 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of C1ORF50 mRNA CTD PMID:12756304 NCBI chr 5:132,837,135...132,841,744
Ensembl chr 5:132,836,506...132,841,762
JBrowse link
G Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of RGP1 mRNA CTD PMID:12756304 NCBI chr 5:57,834,467...57,843,087
Ensembl chr 5:57,834,629...57,843,086
JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RIMS2 mRNA CTD PMID:12756304 NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491
JBrowse link
G Rnf187 ring finger protein 187 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of RNF187 mRNA CTD PMID:12756304 NCBI chr10:43,709,493...43,715,392
Ensembl chr10:43,702,357...43,716,157
JBrowse link
G Ror1 receptor tyrosine kinase-like orphan receptor 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of ROR1 mRNA CTD PMID:12756304 NCBI chr 5:114,744,311...115,088,155
Ensembl chr 5:114,744,304...115,088,155
JBrowse link
G Rpl10 ribosomal protein L10 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of RPL10 mRNA CTD PMID:19013360 NCBI chr  X:152,054,547...152,056,757
Ensembl chr  X:152,054,452...152,056,761
JBrowse link
G Rprm reprimo, TP53 dependent G2 arrest mediator homolog increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPRM mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPRM mRNA]
CTD PMID:18778698 NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPS6KA2 mRNA CTD PMID:19013360 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739
JBrowse link
G Rrh retinal pigment epithelium derived rhodopsin homolog increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RRH mRNA CTD PMID:19013360 NCBI chr 2:218,362,195...218,375,202
Ensembl chr 2:218,362,200...218,374,599
JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RRM2B mRNA CTD PMID:33645215 NCBI chr 7:69,077,024...69,108,742
Ensembl chr 7:69,078,291...69,108,633
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of RUNX2 protein; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of RUNX2 protein CTD PMID:19913120 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A4 mRNA CTD PMID:19013360 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A6 mRNA CTD PMID:19013360 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A8 mRNA CTD PMID:19013360 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of S100A9 mRNA CTD PMID:19013360 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Scg3 secretogranin III increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SCG3 mRNA CTD PMID:19013360 NCBI chr 8:76,399,777...76,442,015
Ensembl chr 8:76,399,777...76,442,015
JBrowse link
G Sec16a SEC16 homolog A, endoplasmic reticulum export factor decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SEC16A mRNA CTD PMID:12756304 NCBI chr 3:9,229,687...9,264,837
Ensembl chr 3:9,229,687...9,264,273
JBrowse link
G Sesn1 sestrin 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SESN1 mRNA CTD PMID:12756304 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
JBrowse link
G Sfn stratifin increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SFN mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SFN mRNA]
CTD PMID:18778698 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sidt2 SID1 transmembrane family, member 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SIDT2 mRNA CTD PMID:12756304 NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC11A2 mRNA CTD PMID:19083439 NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
JBrowse link
G Slc25a39 solute carrier family 25, member 39 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC25A39 mRNA CTD PMID:19013360 NCBI chr10:87,362,494...87,367,358
Ensembl chr10:87,362,490...87,367,260
JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression
multiple interactions
ISO
EXP
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A1 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of SLC30A1 mRNA]
[Zinc co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of SLC30A1 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of SLC30A1 mRNA]; ochratoxin A promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A1 mRNA]; Zinc inhibits the reaction [ochratoxin A promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A1 mRNA]]
CTD PMID:12756304 PMID:17018880 PMID:19720134 PMID:23056475 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc30a5 solute carrier family 30 member 5 multiple interactions
increases expression
decreases expression
ISO [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with ochratoxin A] results in decreased expression of SLC30A5 mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in decreased expression of SLC30A5 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC30A5 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC30A5 mRNA
CTD PMID:15276077 PMID:17234632 PMID:19720134 NCBI chr 2:31,945,745...31,975,969
Ensembl chr 2:31,945,729...31,975,934
JBrowse link
G Slc30a6 solute carrier family 30 member 6 multiple interactions ISO [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with ochratoxin A] results in decreased expression of SLC30A6 mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of SLC30A6 mRNA CTD PMID:19720134 NCBI chr 6:21,020,931...21,050,785
Ensembl chr 6:21,020,931...21,050,785
JBrowse link
G Slc30a7 solute carrier family 30 member 7 multiple interactions
increases expression
ISO [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with ochratoxin A co-treated with Zinc] results in decreased expression of SLC30A7 mRNA; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of SLC30A7 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [ochratoxin A results in decreased expression of SLC30A7 mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC30A7 mRNA
CTD PMID:15276077 PMID:17068819 PMID:19720134 NCBI chr 2:203,855,484...203,922,155
Ensembl chr 2:203,859,175...203,922,132
JBrowse link
G Slc30a8 solute carrier family 30 member 8 multiple interactions EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Glucose results in decreased expression of SLC30A8 mRNA] CTD PMID:23056475 NCBI chr 7:83,591,993...83,627,786
Ensembl chr 7:83,591,993...83,626,305
JBrowse link
G Slc39a1 solute carrier family 39 member 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A1 mRNA CTD PMID:17622302 NCBI chr 2:175,703,413...175,709,063
Ensembl chr 2:175,703,441...175,709,058
JBrowse link
G Slc39a10 solute carrier family 39 member 10 multiple interactions
increases expression
ISO [ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in decreased expression of SLC39A10 mRNA; [ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SLC39A10 mRNA; [Zinc co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SLC39A10 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 protein
Dactinomycin inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [MTF1 protein binds to SLC39A10 promoter]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 mRNA]
CTD PMID:19720134 PMID:21738690 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
JBrowse link
G Slc39a13 solute carrier family 39 member 13 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A13 mRNA CTD PMID:22228435 NCBI chr 3:77,039,411...77,047,536
Ensembl chr 3:77,037,565...77,049,226
JBrowse link
G Slc39a14 solute carrier family 39 member 14 multiple interactions ISO [ochratoxin A co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SLC39A14 mRNA CTD PMID:19720134 NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524
JBrowse link
G Slc39a2 solute carrier family 39 member 2 decreases expression
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A2 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A2 mRNA
CTD PMID:12756304 PMID:18385089 NCBI chr15:24,590,738...24,592,850
Ensembl chr15:24,590,738...24,592,850
JBrowse link
G Slc39a4 solute carrier family 39 member 4 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A4 mRNA CTD PMID:18020946 PMID:19083439 NCBI chr 7:108,333,380...108,337,553
Ensembl chr 7:108,333,381...108,337,553
JBrowse link
G Slc39a5 solute carrier family 39 member 5 decreases response to substance ISO SLC39A5 protein results in decreased susceptibility to N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine CTD PMID:15322118 NCBI chr 7:822,873...830,865
Ensembl chr 7:824,818...830,242
JBrowse link
G Slc39a6 solute carrier family 39 member 6 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form results in decreased susceptibility to trichostatin A]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2 protein]]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in decreased expression of BCL2L1 protein]]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased cleavage of CASP3 protein]]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form inhibits the reaction [trichostatin A results in increased expression of BAX protein]]]; Zinc inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [SLC39A6 mutant form results in decreased susceptibility to trichostatin A]] CTD PMID:19887557 NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417
JBrowse link
G Slc7a1 solute carrier family 7 member 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC7A1 mRNA CTD PMID:12756304 NCBI chr12:6,628,214...6,703,849
Ensembl chr12:6,628,007...6,703,849
JBrowse link
G Slc9a6 solute carrier family 9 member A6 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC9A6 mRNA CTD PMID:12756304 NCBI chr  X:134,430,588...134,486,747
Ensembl chr  X:134,420,756...134,485,375
JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLCO1C1 mRNA CTD PMID:17622302 PMID:19013360 NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289
JBrowse link
G Smim7 small integral membrane protein 7 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SMIM7 mRNA CTD PMID:12756304 NCBI chr16:17,274,417...17,278,336
Ensembl chr16:17,273,258...17,278,336
JBrowse link
G Snap25 synaptosome associated protein 25 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Botulinum Toxins, Type A results in increased cleavage of SNAP25 protein] CTD PMID:11181932 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SOD1 mRNA
[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine binds to Zinc] inhibits the reaction [SOD1 protein binds to Oligodeoxyribonucleotides]
CTD PMID:12888634 PMID:31162603 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Spen spen family transcriptional repressor decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SPEN mRNA CTD PMID:12756304 NCBI chr 5:153,775,287...153,848,677
Ensembl chr 5:153,776,234...153,848,811
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [zinc chloride co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased expression of SPP1 mRNA; [zinc chloride deficiency co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in decreased expression of SPP1 mRNA CTD PMID:19913120 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Zinc results in increased phosphorylation of SRC protein] CTD PMID:12972402 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SRSF5 mRNA CTD PMID:12756304 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of STAT1 mRNA CTD PMID:19013360 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA]
CTD PMID:18778698 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [IL2 protein results in increased phosphorylation of STAT5A protein] CTD PMID:20201035 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [IL2 protein results in increased phosphorylation of STAT5B protein] CTD PMID:20201035 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Steap4 STEAP4 metalloreductase increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of STEAP4 mRNA CTD PMID:12756304 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859
JBrowse link
G Stk10 serine/threonine kinase 10 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STK10 mRNA CTD PMID:12756304 NCBI chr10:17,117,860...17,212,065
Ensembl chr10:17,117,878...17,212,061
JBrowse link
G Synrg synergin, gamma decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SYNRG mRNA CTD PMID:12756304 NCBI chr10:68,848,828...68,931,252 JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TBC1D8 mRNA CTD PMID:12756304 NCBI chr 9:41,651,394...41,761,432
Ensembl chr 9:41,651,395...41,761,409
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TGFBR2 mRNA CTD PMID:12756304 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Thop1 thimet oligopeptidase 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of THOP1 mRNA CTD PMID:19013360 NCBI chr 7:8,632,911...8,645,339
Ensembl chr 7:8,632,916...8,645,275
JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TIMP3 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TIMP3 mRNA]
CTD PMID:18778698 NCBI chr 7:17,520,827...17,571,871
Ensembl chr 7:17,521,919...17,571,839
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TLE1 mRNA CTD PMID:12756304 NCBI chr 5:85,851,827...85,934,806
Ensembl chr 5:85,851,827...85,934,774
JBrowse link
G Tmem184c transmembrane protein 184C increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TMEM184C mRNA CTD PMID:12756304 NCBI chr19:30,345,183...30,361,275
Ensembl chr19:30,345,290...30,361,269
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased activity of CASP3 protein; [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein; [IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [[Calcitriol co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased secretion of TNF protein]; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CDH1 protein]; Zinc inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] results in increased cleavage of CTNNB1 protein]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of TNF mRNA]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [FCER1A protein results in increased expression of TNF protein]
CTD PMID:16818790 PMID:16844947 PMID:20089671 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip8 TNF alpha induced protein 8 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TNFAIP8 mRNA CTD PMID:12756304 NCBI chr18:43,183,854...43,299,517
Ensembl chr18:43,183,916...43,299,517
JBrowse link
G Tns3 tensin 3 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TNS3 mRNA CTD PMID:12756304 NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
JBrowse link
G Tp53 tumor protein p53 affects localization
multiple interactions
increases expression
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine affects the localization of TP53 protein
[Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of LATS2 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of STAT3 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of KRT8 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RB1 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of RPRM mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SFN mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TIMP3 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP73 mRNA]; TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of YWHAZ mRNA]
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP53 protein
CTD PMID:12888634 PMID:18778698 PMID:18951928 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp73 tumor protein p73 increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP73 mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TP73 mRNA]
CTD PMID:18778698 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Trak1 trafficking kinesin protein 1 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TRAK1 mRNA CTD PMID:12756304 NCBI chr 8:120,984,445...121,139,357
Ensembl chr 8:120,984,431...121,139,367
JBrowse link
G Tst thiosulfate sulfurtransferase decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of TST mRNA CTD PMID:12756304 NCBI chr 7:109,948,061...109,955,378
Ensembl chr 7:109,948,062...109,957,216
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TXNIP mRNA CTD PMID:19013360 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Tyms thymidylate synthetase increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of TYMS mRNA CTD PMID:12888634 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of UGCG mRNA CTD PMID:12756304 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Ung uracil-DNA glycosylase increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of UNG mRNA CTD PMID:12888634 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206
JBrowse link
G Usp24 ubiquitin specific peptidase 24 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of USP24 mRNA CTD PMID:12756304 NCBI chr 5:121,080,687...121,210,321
Ensembl chr 5:121,080,470...121,210,311
JBrowse link
G Usp5 ubiquitin specific peptidase 5 multiple interactions ISO 3-cyanoalanine inhibits the reaction [[N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of USP5 protein]; [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Cyclophosphamide] results in increased expression of USP5 protein CTD PMID:29129814 NCBI chr 4:157,619,643...157,634,711
Ensembl chr 4:157,619,643...157,634,711
JBrowse link
G Uvrag UV radiation resistance associated increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of UVRAG mRNA CTD PMID:12888634 NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136
JBrowse link
G Vdac1 voltage-dependent anion channel 1 decreases expression
increases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC1 mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of VDAC1 protein
Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC1 mRNA]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of VDAC1 protein]
CTD PMID:21605504 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Vdac2 voltage-dependent anion channel 2 decreases expression
multiple interactions
EXP N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 mRNA; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 protein
Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 mRNA]; Zinc Sulfate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VDAC2 protein]
CTD PMID:21605504 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
increases secretion
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VEGFA mRNA
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased secretion of VEGFA protein
CTD PMID:18615482 PMID:20957409 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of VPS33B mRNA CTD PMID:12756304 NCBI chr 1:134,223,967...134,247,232
Ensembl chr 1:134,223,949...134,246,970
JBrowse link
G Vsir V-set immunoregulatory receptor increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of VSIR mRNA CTD PMID:19013360 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
JBrowse link
G Wipf2 WAS/WASL interacting protein family, member 2 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of WIPF2 mRNA CTD PMID:12756304 NCBI chr10:83,821,067...83,861,634
Ensembl chr10:83,821,068...83,857,028
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor increases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of XPC mRNA CTD PMID:33645215 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010
JBrowse link
G Yju2b YJU2 splicing factor homolog B decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of YJU2B mRNA CTD PMID:12756304 NCBI chr19:23,894,587...23,906,084
Ensembl chr19:23,894,649...23,906,077
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta increases expression
multiple interactions
ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of YWHAZ mRNA
TP53 mutant form inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of YWHAZ mRNA]
CTD PMID:18778698 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
G Zcchc8 zinc finger CCHC-type containing 8 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZCCHC8 mRNA CTD PMID:12756304 NCBI chr12:32,869,170...32,892,707
Ensembl chr12:32,869,310...32,891,325
JBrowse link
G Zfp141 zinc finger protein 141 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZNF816 mRNA CTD PMID:12756304 NCBI chr 1:93,130,574...93,164,324 JBrowse link
G Zfp36 zinc finger protein 36 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZFP36 mRNA CTD PMID:12756304 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp512b zinc finger protein 512B decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZNF512B mRNA CTD PMID:12756304 NCBI chr 3:168,687,520...168,698,067
Ensembl chr 3:168,687,521...168,698,091
JBrowse link
G Zfp64 zinc finger protein 64 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZFP64 mRNA CTD PMID:12756304 NCBI chr 3:157,666,819...157,695,774
Ensembl chr 3:157,633,211...157,695,809
JBrowse link
G Zfp764 zinc finger protein 764 decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZNF764 mRNA CTD PMID:12756304 NCBI chr 1:182,002,868...182,013,202
Ensembl chr 1:182,009,896...182,013,252
JBrowse link
G Zfpm1 zinc finger protein, multitype 1 multiple interactions ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [GATA1 protein binds to ZFPM1 protein] CTD PMID:33149232 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591
JBrowse link
G Zfta zinc finger translocation associated decreases expression ISO N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZFTA mRNA CTD PMID:12756304 NCBI chr 1:204,603,806...204,612,845
Ensembl chr 1:204,604,103...204,612,688
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      chemical role 19336
        ligand 5819
          chelator 5805
            N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine 281
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    main group molecular entity 19708
                      s-block molecular entity 19493
                        hydrogen molecular entity 19488
                          hydrides 18845
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        polyamine 8267
                                          diamine 8196
                                            primary diamine 5674
                                              alkane-alpha,omega-diamine 3759
                                                ethylenediamine 3734
                                                  N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine 281
paths to the root