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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:brilliant green cation
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Accession:CHEBI:88176 term browser browse the term
Definition:An iminium ion that is the cationic component of the histological dye 'brilliant green'.
Synonyms:exact_synonym: 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium
 related_synonym: Formula=C27H33N2;   InChI=1S/C27H33N2/c1-5-28(6-2)25-18-14-23(15-19-25)27(22-12-10-9-11-13-22)24-16-20-26(21-17-24)29(7-3)8-4/h9-21H,5-8H2,1-4H3/q+1;   InChIKey=HXCILVUBKWANLN-UHFFFAOYSA-N;   SMILES=C(C=1C=CC=CC1)(C=2C=CC(=CC2)N(CC)CC)=C3C=CC(C=C3)=[N+](CC)CC;   brilliant green(1+)
 xref: Drug_Central:4665


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brilliant green term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO brilliant green results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:26177467 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO brilliant green results in increased cleavage of and results in increased activity of CASP7 protein CTD PMID:26177467 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO brilliant green results in decreased expression of CCND1 protein CTD PMID:26177467 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO brilliant green results in decreased expression of IKBKE protein CTD PMID:26177467 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression ISO brilliant green results in increased expression of LONP1 mRNA CTD PMID:21215310 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO brilliant green inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Txn1 thioredoxin 1 increases oxidation ISO brilliant green results in increased oxidation of TXN protein CTD PMID:21215310 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txn2 thioredoxin 2 decreases expression
multiple interactions
affects response to substance		 ISO brilliant green results in decreased expression of TXN2 protein
brilliant green results in increased oxidation of and results in increased degradation of TXN2 protein
TXN2 protein affects the susceptibility to brilliant green		 CTD PMID:21215310 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      chemical role 19507
        environmental contaminant 18882
          brilliant green cation 8
            brilliant green 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      p-block molecular entity 19826
                        carbon group molecular entity 19766
                          organic molecular entity 19785
                            organic ion 11438
                              organic cation 8948
                                iminium ion 98
                                  brilliant green cation 8
                                    brilliant green 8
paths to the root