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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:brilliant green
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Accession:CHEBI:88173 term browser browse the term
Definition:An organic hydrogensulfate salt having 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium as the counterion.
Synonyms:exact_synonym: 4-{[4-(diethylamino)phenyl](phenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium hydrogen sulfate
 related_synonym: (4-(4-(Diethylamino)benzhydrylene)cyclohexa-2,5-dien-1-ylidene)diethylammonium hydrogen sulphate;   Basic green 1;   C.I. 42040;   C.I. Basic Green 1;   Formula=C27H34N2O4S;   InChI=1S/C27H33N2.H2O4S/c1-5-28(6-2)25-18-14-23(15-19-25)27(22-12-10-9-11-13-22)24-16-20-26(21-17-24)29(7-3)8-4;1-5(2,3)4/h9-21H,5-8H2,1-4H3;(H2,1,2,3,4)/q+1;/p-1;   InChIKey=NNBFNNNWANBMTI-UHFFFAOYSA-M;   Malachite green G;   SMILES=C(C=1C=CC=CC1)(C=2C=CC(=CC2)N(CC)CC)=C3C=CC(C=C3)=[N+](CC)CC.OS([O-])(=O)=O
 xref: CAS:633-03-4
 xref_mesh: MESH:C006798
 xref: PMID:25286113;   PMID:25286114;   PMID:25514135;   PMID:26177467;   PMID:26231977;   PMID:26291760;   PMID:26318700;   PMID:26392090;   Wikipedia:Brilliant_Green_(dye)


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brilliant green term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO brilliant green results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:26177467 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions ISO brilliant green results in increased cleavage of and results in increased activity of CASP7 protein CTD PMID:26177467 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO brilliant green results in decreased expression of CCND1 protein CTD PMID:26177467 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon decreases expression ISO brilliant green results in decreased expression of IKBKE protein CTD PMID:26177467 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression ISO brilliant green results in increased expression of LONP1 mRNA CTD PMID:21215310 NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO brilliant green inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Txn1 thioredoxin 1 increases oxidation ISO brilliant green results in increased oxidation of TXN protein CTD PMID:21215310 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txn2 thioredoxin 2 decreases expression
affects response to substance
multiple interactions
ISO brilliant green results in decreased expression of TXN2 protein
TXN2 protein affects the susceptibility to brilliant green
brilliant green results in increased oxidation of and results in increased degradation of TXN2 protein
CTD PMID:21215310 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        poison 18316
          brilliant green 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      chalcogen 19460
                        oxygen atom 19436
                          oxygen molecular entity 19436
                            oxide 11757
                              oxoanion 8899
                                chalcogen oxoanion 541
                                  sulfur oxoanion 540
                                    hydrogensulfate 8
                                      organic hydrogensulfate salt 8
                                        brilliant green 8
paths to the root