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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(R)-prasugrel hydrochloride
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Accession:CHEBI:87714 term browser browse the term
Definition:A hydrochloride obtained by reaction of (R)-prasugrel with one equivalent of hydrochloric acid (the racemic salt is a cardiovascular drug).
Synonyms:exact_synonym: 2-(acetyloxy)-5-[(1R)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-ium chloride;   5-[(1R)-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
 related_synonym: Formula=C20H21ClFNO3S;   InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H/t19-;/m1./s1;   InChIKey=JALHGCPDPSNJNY-FSRHSHDFSA-N;   SMILES=Cl.N1(CCC2=C(C1)C=C(S2)OC(C)=O)[C@H](C3=C(C=CC=C3)F)C(=O)C4CC4
 cyclic_relationship: is_enantiomer_of CHEBI:87708



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prasugrel hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor multiple interactions EXP Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of BDNF protein] CTD PMID:34174262 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased phosphorylation of CREB1 protein] CTD PMID:34174262 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Mir22 microRNA 22 multiple interactions EXP Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of MIR22 mRNA] CTD PMID:34174262 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased sumoylation of NFKBIA protein] CTD PMID:34174262 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G P2ry12 purinergic receptor P2Y12 multiple interactions ISO Prasugrel Hydrochloride binds to and results in decreased activity of P2RY12 protein CTD PMID:17681285 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of SIRT1 protein] CTD PMID:34174262 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I multiple interactions EXP Prasugrel Hydrochloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of UBE2I protein] CTD PMID:34174262 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    chemical entity 20049
      molecular entity 20047
        ion 16332
          organic ion 9186
            organic cation 8124
              (R)-prasugrel(1+) 7
                (R)-prasugrel hydrochloride 7
                  prasugrel hydrochloride 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      halogen 18473
                        chlorine atom 18327
                          chlorine molecular entity 18327
                            elemental chlorine 8473
                              monoatomic chlorine 8456
                                chloride 8456
                                  chloride salt 8456
                                    organic chloride salt 925
                                      hydrochloride 694
                                        (R)-prasugrel hydrochloride 7
                                          prasugrel hydrochloride 7
paths to the root