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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:prasugrel hydrochloride
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Accession:CHEBI:87697 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-prasugrel hydrochloride. Used to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.
Synonyms:exact_synonym: rac-2-(acetyloxy)-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-ium chloride;   rac-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
 related_synonym: (RS)-prasugrel hydrochloride;   5-((1RS)-2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridin-2-yl acetate hydrochloride;   Effient;   LY 640315;   LY640315;   rac-prasugrel hydrochloride;   racemic prasugrel hydrochloride
 xref: CAS:389574-19-0;   DrugBank:DB06209;   KEGG:D05597
 xref_mesh: MESH:D000068799
 xref: PMID:25527979;   PMID:25633751;   PMID:26051687;   PMID:26114771;   Reaxys:11182898;   Wikipedia:Prasugrel


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prasugrel hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y12 multiple interactions ISO Prasugrel Hydrochloride binds to and results in decreased activity of P2RY12 protein CTD PMID:17681285 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      chemical substance 11959
        mixture 10880
          racemate 9777
            prasugrel hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      halogen 18074
                        chlorine atom 17866
                          chlorine molecular entity 17866
                            elemental chlorine 8382
                              monoatomic chlorine 8363
                                chloride 8363
                                  chloride salt 8363
                                    organic chloride salt 666
                                      hydrochloride 436
                                        (S)-prasugrel hydrochloride 1
                                          prasugrel hydrochloride 1
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