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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:prasugrel hydrochloride
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Accession:CHEBI:87697 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-prasugrel hydrochloride. Used to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.
Synonyms:exact_synonym: rac-2-(acetyloxy)-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-ium chloride;   rac-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
 related_synonym: (RS)-prasugrel hydrochloride;   5-((1RS)-2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridin-2-yl acetate hydrochloride;   Effient;   LY 640315;   LY640315;   rac-prasugrel hydrochloride;   racemic prasugrel hydrochloride
 xref: CAS:389574-19-0;   DrugBank:DB06209;   KEGG:D05597
 xref_mesh: MESH:D000068799
 xref: PMID:25527979;   PMID:25633751;   PMID:26051687;   PMID:26114771;   Reaxys:11182898;   Wikipedia:Prasugrel


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prasugrel hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y, G-protein coupled 12 multiple interactions EXP Prasugrel Hydrochloride binds to and results in decreased activity of P2RY12 protein CTD PMID:17681285 NCBI chr 3:59,216,271...59,262,985
Ensembl chr 3:59,216,272...59,262,871
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21552
    chemical entity 21550
      chemical substance 12326
        mixture 11167
          racemate 10047
            prasugrel hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 21552
    subatomic particle 21537
      composite particle 21537
        hadron 21537
          baryon 21537
            nucleon 21537
              atomic nucleus 21537
                atom 21537
                  main group element atom 21442
                    p-block element atom 21442
                      halogen 19401
                        chlorine atom 19019
                          chlorine molecular entity 19019
                            elemental chlorine 8232
                              monoatomic chlorine 8213
                                chloride 8213
                                  chloride salt 8213
                                    organic chloride salt 907
                                      hydrochloride 672
                                        (S)-prasugrel hydrochloride 1
                                          prasugrel hydrochloride 1
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