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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:prasugrel hydrochloride
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Accession:CHEBI:87697 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-prasugrel hydrochloride. Used to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.
Synonyms:exact_synonym: rac-2-(acetyloxy)-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-ium chloride;   rac-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochloride
 related_synonym: (RS)-prasugrel hydrochloride;   5-((1RS)-2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridin-2-yl acetate hydrochloride;   Effient;   LY 640315;   LY640315;   rac-prasugrel hydrochloride;   racemic prasugrel hydrochloride
 xref: CAS:389574-19-0;   DrugBank:DB06209;   KEGG:D05597
 xref_mesh: MESH:D000068799
 xref: PMID:25527979;   PMID:25633751;   PMID:26051687;   PMID:26114771;   Reaxys:11182898;   Wikipedia:Prasugrel


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prasugrel hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2ry12 purinergic receptor P2Y12 multiple interactions ISO Prasugrel Hydrochloride binds to and results in decreased activity of P2RY12 protein CTD PMID:17681285 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      chemical substance 11928
        mixture 10845
          racemate 9741
            prasugrel hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      halogen 18011
                        chlorine atom 17793
                          chlorine molecular entity 17793
                            elemental chlorine 8373
                              monoatomic chlorine 8354
                                chloride 8354
                                  chloride salt 8354
                                    organic chloride salt 664
                                      hydrochloride 435
                                        (S)-prasugrel hydrochloride 1
                                          prasugrel hydrochloride 1
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