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ONTOLOGY REPORT - ANNOTATIONS


Term:ranolazine
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Accession:CHEBI:87681 term browser browse the term
Definition:A racemate comprising equal amounts of (R)- and (S)-ranolazine. Used for treatment of chronic angina.
Synonyms:exact_synonym: rac-N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide
 related_synonym: (+-)-N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide;   (RS)-ranolazine;   Formula=C24H33N3O4;   Ranexa;   rac-ranolazine;   racemic ranolazine
 xref: CAS:95635-55-5 "ChemIDplus";   CAS:95635-55-5 "KEGG DRUG";   DrugBank:DB00243;   KEGG:D05700
 xref_mesh: MESH:D000069458
 xref: PMID:25041234 "Europe PMC";   PMID:25188881 "Europe PMC";   PMID:25210025 "Europe PMC";   PMID:25346368 "Europe PMC";   PMID:25346483 "Europe PMC";   PMID:25416563 "Europe PMC";   PMID:25496982 "Europe PMC";   PMID:25515836 "Europe PMC";   PMID:25544118 "Europe PMC";   PMID:25555283 "Europe PMC";   PMID:25602175 "Europe PMC";   PMID:25738014 "Europe PMC";   PMID:25761430 "Europe PMC";   PMID:25828315 "Europe PMC";   PMID:25848292 "Europe PMC";   PMID:25872749 "Europe PMC";   PMID:26021246 "Europe PMC";   PMID:26049552 "Europe PMC";   PMID:26049922 "Europe PMC";   PMID:26059896 "Europe PMC";   PMID:26138210 "Europe PMC";   PMID:26183665 "Europe PMC";   PMID:26185330 "Europe PMC";   PMID:26226999 "Europe PMC";   PMID:26245658 "Europe PMC";   Patent:EP126449;   Patent:US4567264;   Reaxys:8234797 "Reaxys";   Wikipedia:Ranolazine


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ranolazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Scn5a sodium voltage-gated channel alpha subunit 5 JBrowse link 8 128,169,191 128,266,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      chemical substance 10725
        mixture 9929
          racemate 8658
            ranolazine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                monocarboxylic acid amide 13180
                                                  N-(2,6-dimethylphenyl)-2-\{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl\}acetamide 3
                                                    (S)-ranolazine 3
                                                      ranolazine 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.