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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hexane-2,3-dione
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Accession:CHEBI:87583 term browser browse the term
Definition:An alpha-diketone that is hexane substituted by oxo groups at positions 2 and 3 respectively.
Synonyms:related_synonym: Formula=C6H10O2;   InChI=1S/C6H10O2/c1-3-4-6(8)5(2)7/h3-4H2,1-2H3;   InChIKey=MWVFCEVNXHTDNF-UHFFFAOYSA-N;   Methyl propyl diketone;   SMILES=CCCC(=O)C(C)=O
 xref: CAS:3848-24-6;   HMDB:HMDB0031491
 xref_mesh: MESH:C043231
 xref: Reaxys:1699896



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hexane-2,3-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1a1 aldo-keto reductase family 1 member A1 increases reduction ISO AKR1A1 protein results in increased reduction of 2,3-hexanedione CTD PMID:10510318 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases reduction
multiple interactions
ISO AKR1B1 protein results in increased reduction of 2,3-hexanedione
[AKR1B1 protein results in increased reduction of 2,3-hexanedione] which results in increased chemical synthesis of Hexanones
CTD PMID:10510318 PMID:23295224 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases reduction
multiple interactions
ISO AKR1B10 protein results in increased reduction of 2,3-hexanedione
[AKR1B10 protein results in increased reduction of 2,3-hexanedione] which results in increased chemical synthesis of Hexanones
CTD PMID:23295224 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Cbr1 carbonyl reductase 1 increases reduction
multiple interactions
ISO CBR1 protein results in increased reduction of 2,3-hexanedione
8-prenylnaringenin inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; [S-Nitrosoglutathione binds to CBR1 protein] inhibits the reaction [CBR1 protein results in increased metabolism of 2,3-hexanedione]; Curcumin inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; isoxanthohumol inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; Quercetin inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]; xanthohumol inhibits the reaction [CBR1 protein results in increased reduction of 2,3-hexanedione]
CTD PMID:23295225 PMID:25541467 PMID:30849340 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        biochemical role 19588
          metabolite 19574
            hexane-2,3-dione 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      ketone 17210
                                        diketone 1259
                                          alpha-diketone 218
                                            hexane-2,3-dione 4
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