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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:erythrosin(2-)
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Accession:CHEBI:87118 term browser browse the term
Definition:A benzoate obtained by deprotonation of the carboxy and phenol groups of erythrosin.
Synonyms:exact_synonym: 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydro-3H-xanthen-9-yl)benzoate
 related_synonym: Formula=C20H8I4O5;   InChI=1S/C20H10I4O5/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25/h1-6,9,18,25H,(H,27,28)/p-2;   InChIKey=WTOSNONTQZJEBC-UHFFFAOYSA-L;   SMILES=[O-]C(=O)c1ccccc1C1=C2C=C(I)C(=O)C(I)=C2OC2C1C=C(I)C([O-])=C2I
 cyclic_relationship: is_conjugate_base_of CHEBI:87117


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erythrosin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO Erythrosine results in decreased activity of ABCB1 protein CTD PMID:20041016 NCBI chr 4:25,357,467...25,529,941 JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Erythrosine results in increased expression of CCND1 protein CTD PMID:8927716 NCBI chr 1:200,089,002...200,098,524 JBrowse link
G Cdk2 cyclin dependent kinase 2 increases activity ISO Erythrosine results in increased activity of CDK2 protein CTD PMID:8927716 PMID:9168006 NCBI chr 7:1,129,878...1,137,431 JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity EXP Erythrosine results in decreased activity of CYP19A1 protein CTD PMID:18310892 NCBI chr 8:54,553,165...54,580,758 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Erythrosine results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:202,754,549...202,763,057 JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Erythrosine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230 JBrowse link
G Hpgds hematopoietic prostaglandin D synthase decreases activity ISO Erythrosine results in decreased activity of HPGDS protein CTD PMID:25603235 NCBI chr 4:94,368,426...94,397,931 JBrowse link
G Iyd iodotyrosine deiodinase decreases activity ISO Erythrosine results in decreased activity of IYD protein CTD PMID:24012475 NCBI chr 1:40,003,999...40,019,323 JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Erythrosine results in increased expression of JUN protein CTD PMID:20025956 NCBI chr 5:109,894,175...109,897,268 JBrowse link
G Orm1 orosomucoid 1 increases expression ISO Erythrosine results in increased expression of ORM1 protein CTD PMID:20025956 NCBI chr 5:76,766,637...76,776,149 JBrowse link
G Phex phosphate regulating endopeptidase homolog, X-linked increases expression ISO Erythrosine results in increased expression of PHEX protein CTD PMID:20025956 NCBI chr  X:37,607,553...37,856,183 JBrowse link
G Tp53 tumor protein p53 increases activity ISO Erythrosine results in increased activity of TP53 protein CTD PMID:9168006 NCBI chr10:54,300,070...54,311,525 JBrowse link
G Trh thyrotropin releasing hormone multiple interactions EXP Erythrosine promotes the reaction [TRH protein results in increased expression of TSHB protein] CTD PMID:2160137 NCBI chr 4:124,742,111...124,777,094 JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP Erythrosine promotes the reaction [TRH protein results in increased expression of TSHB protein] CTD PMID:2160137 NCBI chr 2:190,224,676...190,229,559 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO Erythrosine results in decreased activity of UGT1A6 protein CTD PMID:20041016 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO Erythrosine results in decreased activity of UGT2B7 protein CTD PMID:20041016 NCBI chr14:20,896,682...20,919,604 JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Erythrosine results in increased expression of VEGFA protein CTD PMID:20025956 NCBI chr 9:14,955,300...14,970,641 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19762
    chemical entity 19762
      molecular entity 19760
        ion 15930
          organic ion 8462
            organic anion 3034
              phenolate anion 18
                erythrosin(2-) 17
                  erythrosin B 17
Path 2
Term Annotations click to browse term
  CHEBI ontology 19762
    subatomic particle 19760
      composite particle 19760
        hadron 19760
          baryon 19760
            nucleon 19760
              atomic nucleus 19760
                atom 19760
                  main group element atom 19651
                    p-block element atom 19651
                      carbon group element atom 19570
                        carbon atom 19560
                          organic molecular entity 19560
                            organic ion 8462
                              organic anion 3034
                                carboxylic acid anion 2394
                                  monocarboxylic acid anion 1500
                                    benzoates 1271
                                      erythrosin(2-) 17
                                        erythrosin B 17
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