Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antibiotic antifungal drug
go back to main search page
Accession:CHEBI:87113 term browser browse the term
Definition:Any antibiotic antifungal agent used to treat fungal infections in humans or animals.
Synonyms:related_synonym: antibiotic antifungal drugs



show annotations for term's descendants           Sort by:
amphotericin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCA1 mRNA CTD PMID:36464106 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 decreases expression ISO Amphotericin B analog results in decreased expression of ABCA12 mRNA CTD PMID:28534445 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB11 mRNA CTD PMID:36464106 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCB1A mRNA CTD PMID:36464106 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA CTD PMID:36464106 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC3 mRNA CTD PMID:36464106 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Amphotericin B analog results in decreased expression of ABCG1 mRNA CTD PMID:28534445 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA CTD PMID:36464106 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA CTD PMID:36464106 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Acrv1 acrosomal vesicle protein 1 increases expression ISO Amphotericin B analog results in increased expression of ACRV1 mRNA CTD PMID:28534445 NCBI chr 8:36,404,394...36,409,971
Ensembl chr 8:36,404,394...36,424,959
JBrowse link
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 increases expression ISO Amphotericin B analog results in increased expression of ADAMTS12 mRNA CTD PMID:28534445 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
G Adcy2 adenylate cyclase 2 increases expression ISO Amphotericin B analog results in increased expression of ADCY2 mRNA CTD PMID:28534445 NCBI chr 1:34,375,639...34,822,252
Ensembl chr 1:34,375,895...34,822,236
JBrowse link
G Adora3 adenosine A3 receptor increases expression ISO Amphotericin B analog results in increased expression of ADORA3 mRNA CTD PMID:28534445 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
JBrowse link
G Adra2a adrenoceptor alpha 2A decreases expression ISO Amphotericin B analog results in decreased expression of ADRA2A mRNA CTD PMID:28534445 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO Amphotericin B analog results in decreased expression of ALDH8A1 mRNA CTD PMID:28534445 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
JBrowse link
G Alk ALK receptor tyrosine kinase increases expression ISO Amphotericin B results in increased expression of ALK mRNA CTD PMID:28534445 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Alox5 arachidonate 5-lipoxygenase decreases expression ISO Amphotericin B analog results in decreased expression of ALOX5 mRNA CTD PMID:28534445 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO Amphotericin B analog results in decreased expression of AMACR mRNA CTD PMID:28534445 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Ank3 ankyrin 3 decreases expression ISO Amphotericin B analog results in decreased expression of ANK3 mRNA CTD PMID:28534445 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Anxa9 annexin A9 decreases expression ISO Amphotericin B analog results in decreased expression of ANXA9 mRNA CTD PMID:28534445 NCBI chr 2:182,873,185...182,884,501
Ensembl chr 2:182,872,929...182,883,374
JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 increases expression ISO Amphotericin B analog results in increased expression of AP3B2 mRNA CTD PMID:28534445 NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191
JBrowse link
G Apbb2 amyloid beta precursor protein binding family B member 2 increases expression ISO Amphotericin B analog results in increased expression of APBB2 mRNA CTD PMID:28534445 NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
JBrowse link
G Apoc2 apolipoprotein C2 increases expression ISO Amphotericin B analog results in increased expression of APOC2 mRNA CTD PMID:28534445 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression ISO Amphotericin B analog results in decreased expression of AQP3 mRNA CTD PMID:28534445 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Aqp5 aquaporin 5 increases expression ISO Amphotericin B analog results in increased expression of AQP5 mRNA CTD PMID:28534445 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
JBrowse link
G Arg2 arginase 2 decreases expression ISO Amphotericin B analog results in decreased expression of ARG2 mRNA CTD PMID:28534445 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
JBrowse link
G Arhgef26 Rho guanine nucleotide exchange factor 26 increases expression ISO Amphotericin B results in increased expression of ARHGEF26 mRNA CTD PMID:20849824 NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer] CTD PMID:16189267 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Arrb1 arrestin, beta 1 increases expression ISO Amphotericin B analog results in increased expression of ARRB1 mRNA CTD PMID:28534445 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061
JBrowse link
G Atg3 autophagy related 3 decreases expression ISO Amphotericin B results in decreased expression of ATG3 mRNA CTD PMID:20849824 NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Atp10b ATPase phospholipid transporting 10B increases expression ISO Amphotericin B analog results in increased expression of ATP10B mRNA CTD PMID:28534445 NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637
JBrowse link
G B3gnt4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 increases expression ISO Amphotericin B analog results in increased expression of B3GNT4 mRNA CTD PMID:28534445 NCBI chr12:33,070,221...33,073,904
Ensembl chr12:33,060,416...33,073,854
JBrowse link
G Bag4 BAG cochaperone 4 decreases expression ISO Amphotericin B analog results in decreased expression of BAG4 mRNA CTD PMID:28534445 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G Bcl6 BCL6, transcription repressor decreases expression ISO Amphotericin B analog results in decreased expression of BCL6 mRNA CTD PMID:28534445 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bend5 BEN domain containing 5 decreases expression ISO Amphotericin B analog results in decreased expression of BEND5 mRNA CTD PMID:28534445 NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367
JBrowse link
G Bmp2 bone morphogenetic protein 2 decreases expression ISO Amphotericin B analog results in decreased expression of BMP2 mRNA; Amphotericin B results in decreased expression of BMP2 mRNA CTD PMID:28534445 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression ISO Amphotericin B analog results in increased expression of BMP7 mRNA CTD PMID:28534445 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Bnc1 basonuclin zinc finger protein 1 increases expression ISO Amphotericin B analog results in increased expression of BNC1 mRNA CTD PMID:28534445 NCBI chr 1:135,917,676...135,943,333
Ensembl chr 1:135,917,687...135,943,333
JBrowse link
G Bora bora, aurora kinase A activator decreases expression ISO Amphotericin B analog results in decreased expression of BORA mRNA CTD PMID:28534445 NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma increases expression ISO Amphotericin B analog results in increased expression of CAMK2G mRNA CTD PMID:28534445 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,504,085...3,563,050
JBrowse link
G Capn6 calpain 6 decreases expression ISO Amphotericin B analog results in decreased expression of CAPN6 mRNA CTD PMID:28534445 NCBI chr  X:107,380,774...107,405,489
Ensembl chr  X:107,380,774...107,405,489
JBrowse link
G Car12 carbonic anhydrase 12 decreases expression ISO Amphotericin B analog results in decreased expression of CA12 mRNA CTD PMID:28534445 NCBI chr 8:67,274,739...67,330,428
Ensembl chr 8:67,274,359...67,330,440
JBrowse link
G Car14 carbonic anhydrase 14 increases expression ISO Amphotericin B analog results in increased expression of CA14 mRNA CTD PMID:28534445 NCBI chr 2:183,442,263...183,449,231
Ensembl chr 2:183,441,667...183,449,693
JBrowse link
G Car4 carbonic anhydrase 4 decreases expression ISO Amphotericin B analog results in decreased expression of CA4 mRNA CTD PMID:28534445 NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
JBrowse link
G Car9 carbonic anhydrase 9 decreases expression ISO Amphotericin B analog results in decreased expression of CA9 mRNA CTD PMID:28534445 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Carf calcium responsive transcription factor decreases expression ISO Amphotericin B analog results in decreased expression of CARF mRNA CTD PMID:28534445 NCBI chr 9:61,502,368...61,552,433
Ensembl chr 9:61,506,956...61,550,462
JBrowse link
G Casp3 caspase 3 increases expression ISO Amphotericin B results in increased expression of CASP3 protein CTD PMID:23988732 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casq2 calsequestrin 2 increases expression ISO Amphotericin B analog results in increased expression of CASQ2 mRNA CTD PMID:28534445 NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267
JBrowse link
G Cat catalase decreases expression EXP Amphotericin B results in decreased expression of CAT mRNA CTD PMID:20623750 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Amphotericin B analog results in increased expression of CCL20 mRNA; Amphotericin B results in increased expression of CCL20 mRNA CTD PMID:28534445 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccne2 cyclin E2 decreases expression ISO Amphotericin B results in decreased expression of CCNE2 mRNA CTD PMID:28534445 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 decreases expression EXP Amphotericin B results in decreased expression of CCR2 mRNA CTD PMID:20623750 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Cd14 CD14 molecule decreases expression ISO Amphotericin B analog results in decreased expression of CD14 mRNA CTD PMID:28534445 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd1d1 CD1d1 molecule decreases expression ISO Amphotericin B analog results in decreased expression of CD1D mRNA CTD PMID:28534445 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Cd2 Cd2 molecule increases expression ISO Amphotericin B analog results in increased expression of CD2 mRNA CTD PMID:28534445 NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex increases expression ISO Amphotericin B analog results in increased expression of CD3E mRNA CTD PMID:28534445 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd84 CD84 molecule increases expression ISO Amphotericin B analog results in increased expression of CD84 mRNA CTD PMID:28534445 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
JBrowse link
G Cdkl5 cyclin-dependent kinase-like 5 increases expression ISO Amphotericin B analog results in increased expression of CDKL5 mRNA CTD PMID:28534445 NCBI chr  X:33,757,605...33,988,075
Ensembl chr  X:33,821,257...33,986,582
JBrowse link
G Cdsn corneodesmosin increases expression ISO Amphotericin B analog results in increased expression of CDSN mRNA CTD PMID:28534445 NCBI chr20:3,179,432...3,184,252
Ensembl chr20:3,179,438...3,184,250
JBrowse link
G Ceacam15 CEA cell adhesion molecule 15 increases expression ISO Amphotericin B analog results in increased expression of CEACAM21 mRNA CTD PMID:28534445 NCBI chr 1:77,368,376...77,373,343
Ensembl chr 1:77,368,966...77,372,663
JBrowse link
G Cep76 centrosomal protein 76 decreases expression ISO Amphotericin B analog results in decreased expression of CEP76 mRNA CTD PMID:28534445 NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression ISO Amphotericin B analog results in increased expression of CGA mRNA CTD PMID:28534445 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Amphotericin B analog results in increased expression of CHAC1 mRNA CTD PMID:28534445 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chi3l1 chitinase 3 like 1 decreases expression ISO Amphotericin B analog results in decreased expression of CHI3L1 mRNA CTD PMID:28534445 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
JBrowse link
G Chl1 cell adhesion molecule L1-like decreases expression ISO Amphotericin B analog results in decreased expression of CHL1 mRNA CTD PMID:28534445 NCBI chr 4:136,291,504...136,505,830
Ensembl chr 4:136,291,463...136,503,265
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 decreases expression ISO Amphotericin B analog results in decreased expression of CHP1 mRNA CTD PMID:28534445 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO Amphotericin B analog results in increased expression of CHRNB3 mRNA CTD PMID:28534445 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Clu clusterin affects expression
decreases expression
EXP
ISO
Amphotericin B affects the expression of CLU mRNA
Amphotericin B analog results in decreased expression of CLU mRNA
CTD PMID:20623750 PMID:28534445 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cmahp cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene decreases expression ISO Amphotericin B analog results in decreased expression of CMAHP mRNA CTD PMID:28534445 NCBI chr17:40,557,161...40,642,350
Ensembl chr17:40,583,667...40,642,275
JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Amphotericin B analog results in increased expression of CNR2 mRNA CTD PMID:28534445 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Cntn5 contactin 5 increases expression ISO Amphotericin B analog results in increased expression of CNTN5 mRNA CTD PMID:28534445 NCBI chr 8:6,735,715...7,967,727
Ensembl chr 8:6,738,239...7,967,957
JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression ISO Amphotericin B analog results in increased expression of COL5A1 mRNA CTD PMID:28534445 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
JBrowse link
G Comt catechol-O-methyltransferase increases expression ISO Amphotericin B analog results in increased expression of COMT mRNA CTD PMID:28534445 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Cpd carboxypeptidase D decreases expression ISO Amphotericin B analog results in decreased expression of CPD mRNA CTD PMID:28534445 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO Amphotericin B analog results in decreased expression of CPT1B mRNA CTD PMID:28534445 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO Amphotericin B analog results in increased expression of CRISPLD2 mRNA CTD PMID:28534445 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
JBrowse link
G Crybb1 crystallin, beta B1 increases expression ISO Amphotericin B analog results in increased expression of CRYBB1 mRNA CTD PMID:28534445 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Amphotericin B analog results in increased expression of CSF2 mRNA; Amphotericin B results in increased expression of CSF2 mRNA CTD PMID:28534445 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 increases expression ISO Amphotericin B analog results in increased expression of CSGALNACT2 mRNA CTD PMID:28534445 NCBI chr 4:151,271,774...151,308,856
Ensembl chr 4:151,277,645...151,308,839
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 decreases expression ISO Amphotericin B analog results in decreased expression of CSPG5 mRNA CTD PMID:28534445 NCBI chr 8:110,220,506...110,234,766
Ensembl chr 8:110,220,653...110,234,758
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO Amphotericin B analog results in increased expression of CXCL1 mRNA CTD PMID:28534445 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Amphotericin B analog results in increased expression of CXCL2 mRNA; Amphotericin B results in increased expression of CXCL2 mRNA CTD PMID:28534445 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression ISO Amphotericin B analog results in increased expression of CXCL1 mRNA CTD PMID:28534445 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Amphotericin B analog results in decreased expression of CXCR4 mRNA CTD PMID:28534445 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA CTD PMID:36464106 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases expression ISO Amphotericin B analog results in increased expression of CYP2C19 mRNA CTD PMID:28534445 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 decreases expression ISO Amphotericin B analog results in decreased expression of CYP4B1 mRNA CTD PMID:28534445 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA CTD PMID:36464106 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7B1 mRNA CTD PMID:36464106 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA CTD PMID:36464106 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Cyth4 cytohesin 4 increases expression ISO Amphotericin B analog results in increased expression of CYTH4 mRNA CTD PMID:28534445 NCBI chr 7:110,152,232...110,176,726
Ensembl chr 7:110,152,272...110,176,741
JBrowse link
G Dclk1 doublecortin-like kinase 1 decreases expression ISO Amphotericin B analog results in decreased expression of DCLK1 mRNA CTD PMID:28534445 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein increases expression ISO Amphotericin B analog results in increased expression of DCSTAMP mRNA CTD PMID:28534445 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Amphotericin B results in increased expression of DDIT3 mRNA CTD PMID:28534445 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx11 DEAD/H-box helicase 11 increases expression ISO Amphotericin B results in increased expression of DDX11 mRNA CTD PMID:28534445 NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein decreases expression ISO Amphotericin B analog results in decreased expression of DEPTOR mRNA CTD PMID:28534445 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 decreases expression ISO Amphotericin B analog results in decreased expression of DHRS7 mRNA CTD PMID:28534445 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
JBrowse link
G Dicer1 dicer 1 ribonuclease III decreases expression ISO Amphotericin B analog results in decreased expression of DICER1 mRNA CTD PMID:28534445 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 increases expression ISO Amphotericin B analog results in increased expression of DKK4 mRNA CTD PMID:28534445 NCBI chr16:69,403,215...69,406,580
Ensembl chr16:69,402,989...69,406,580
JBrowse link
G Dlgap1 DLG associated protein 1 decreases expression
increases expression
ISO Amphotericin B analog results in decreased expression of DLGAP1 mRNA
Amphotericin B analog results in increased expression of DLGAP1 mRNA
CTD PMID:28534445 NCBI chr 9:109,857,500...110,726,817
Ensembl chr 9:110,167,448...110,726,817
JBrowse link
G Dnah3 dynein, axonemal, heavy chain 3 increases expression ISO Amphotericin B analog results in increased expression of DNAH3 mRNA CTD PMID:28534445 NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 increases expression ISO Amphotericin B analog results in increased expression of DNAJA4 mRNA CTD PMID:28534445 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 decreases expression ISO Amphotericin B analog results in decreased expression of DTX4 mRNA CTD PMID:28534445 NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
JBrowse link
G Duox2 dual oxidase 2 increases expression ISO Amphotericin B analog results in increased expression of DUOX2 mRNA CTD PMID:28534445 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
JBrowse link
G Dzip3 DAZ interacting zinc finger protein 3 decreases expression ISO Amphotericin B analog results in decreased expression of DZIP3 mRNA CTD PMID:28534445 NCBI chr11:51,823,235...51,893,353
Ensembl chr11:51,823,231...51,893,353
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO Amphotericin B analog results in increased expression of E2F2 mRNA CTD PMID:28534445 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Amphotericin B results in increased expression of EDNRB mRNA CTD PMID:20849824 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Efr3b EFR3 homolog B increases expression ISO Amphotericin B analog results in increased expression of EFR3B mRNA CTD PMID:28534445 NCBI chr 6:26,947,436...27,021,113
Ensembl chr 6:26,948,540...27,020,933
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 decreases expression ISO Amphotericin B analog results in decreased expression of EGLN3 mRNA CTD PMID:28534445 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766
JBrowse link
G Emx2 empty spiracles homeobox 2 decreases expression ISO Amphotericin B analog results in decreased expression of EMX2 mRNA CTD PMID:28534445 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594
JBrowse link
G Eno1 enolase 1 multiple interactions ISO Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of ENO1 mRNA]; Amphotericin B results in increased expression of and results in increased secretion of ENO1 protein CTD PMID:16189267 PMID:26259607 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression ISO Amphotericin B analog results in decreased expression of ENPP2 mRNA CTD PMID:28534445 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:16189267 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epo erythropoietin multiple interactions
decreases expression
ISO
EXP
Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of EPO mRNA]
Amphotericin B results in decreased expression of EPO protein
CTD PMID:697352 PMID:2299214 PMID:16189267 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Epor erythropoietin receptor increases expression ISO Amphotericin B analog results in increased expression of EPOR mRNA; Amphotericin B results in increased expression of EPOR mRNA CTD PMID:28534445 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
JBrowse link
G Ereg epiregulin increases expression ISO Amphotericin B analog results in increased expression of EREG mRNA CTD PMID:28534445 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Fam13a family with sequence similarity 13, member A decreases expression ISO Amphotericin B analog results in decreased expression of FAM13A mRNA CTD PMID:28534445 NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA CTD PMID:36464106 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbln1 fibulin 1 increases expression ISO Amphotericin B analog results in increased expression of FBLN1 mRNA CTD PMID:28534445 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Fcgr1a Fc gamma receptor 1A increases expression ISO Amphotericin B analog results in increased expression of FCGR1A mRNA CTD PMID:28534445 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fgb fibrinogen beta chain decreases expression ISO Amphotericin B analog results in decreased expression of FGB mRNA CTD PMID:28534445 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgf4 fibroblast growth factor 4 increases expression ISO Amphotericin B analog results in increased expression of FGF4 mRNA CTD PMID:28534445 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO Amphotericin B analog results in decreased expression of FKBP5 mRNA CTD PMID:28534445 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 decreases expression ISO Amphotericin B analog results in decreased expression of FLRT3 mRNA; Amphotericin B results in decreased expression of FLRT3 mRNA CTD PMID:28534445 NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Amphotericin B analog results in increased expression of FOSB mRNA CTD PMID:28534445 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Frmd4b FERM domain containing 4B decreases expression ISO Amphotericin B analog results in decreased expression of FRMD4B mRNA CTD PMID:28534445 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197
JBrowse link
G Fsbp fibrinogen silencer binding protein decreases expression ISO Amphotericin B analog results in decreased expression of FSBP mRNA CTD PMID:28534445 NCBI chr 5:25,058,003...25,064,276
Ensembl chr 5:25,032,066...25,104,616
JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression ISO Amphotericin B analog results in decreased expression of FUBP1 mRNA CTD PMID:28534445 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Fxr1 FMR1 autosomal homolog 1 decreases expression ISO Amphotericin B analog results in decreased expression of FXR1 mRNA CTD PMID:28534445 NCBI chr 2:116,884,167...116,937,590
Ensembl chr 2:116,884,248...116,937,590
JBrowse link
G Fxyd3 FXYD domain-containing ion transport regulator 3 increases expression ISO Amphotericin B analog results in increased expression of FXYD3 mRNA CTD PMID:28534445 NCBI chr 1:86,305,531...86,312,455 JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 decreases expression ISO Amphotericin B analog results in decreased expression of GAL3ST1 mRNA CTD PMID:28534445 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388
JBrowse link
G Galr3 galanin receptor 3 increases expression ISO Amphotericin B analog results in increased expression of GALR3 mRNA CTD PMID:28534445 NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Amphotericin B analog results in increased expression of GDF15 mRNA; Amphotericin B results in increased expression of GDF15 mRNA CTD PMID:28534445 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gfra3 GDNF family receptor alpha 3 increases expression ISO Amphotericin B analog results in increased expression of GFRA3 mRNA CTD PMID:28534445 NCBI chr18:26,297,828...26,326,105
Ensembl chr18:26,297,829...26,326,105
JBrowse link
G Gfra4 GDNF family receptor alpha 4 increases expression ISO Amphotericin B analog results in increased expression of GFRA4 mRNA CTD PMID:28534445 NCBI chr 3:118,254,937...118,262,252
Ensembl chr 3:118,255,402...118,258,329
JBrowse link
G Glce glucuronic acid epimerase decreases expression ISO Amphotericin B analog results in decreased expression of GLCE mRNA CTD PMID:28534445 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040
JBrowse link
G Glod4 glyoxalase domain containing 4 decreases expression ISO Amphotericin B results in decreased expression of GLOD4 mRNA CTD PMID:20849824 NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898
JBrowse link
G Gls glutaminase increases expression ISO Amphotericin B analog results in increased expression of GLS mRNA CTD PMID:28534445 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO Amphotericin B analog results in decreased expression of GLUL mRNA CTD PMID:28534445 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha increases expression ISO Amphotericin B analog results in increased expression of GP1BA mRNA CTD PMID:28534445 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gpr20 G protein-coupled receptor 20 increases expression ISO Amphotericin B results in increased expression of GPR20 mRNA CTD PMID:20849824 NCBI chr 7:105,601,761...105,611,959
Ensembl chr 7:105,602,368...105,603,430
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein CTD PMID:36464106 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 increases expression ISO Amphotericin B analog results in increased expression of GRID2 mRNA CTD PMID:28534445 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355
JBrowse link
G Grm6 glutamate metabotropic receptor 6 increases expression ISO Amphotericin B analog results in increased expression of GRM6 mRNA CTD PMID:28534445 NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression
multiple interactions
EXP
ISO
Amphotericin B results in decreased expression of GSTP1 mRNA
Amphotericin B inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
CTD PMID:20623750 PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression EXP Amphotericin B results in decreased expression of GSTT1 mRNA CTD PMID:20623750 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G H2ac4 H2A clustered histone 4 decreases expression ISO Amphotericin B analog results in decreased expression of HIST1H2AC mRNA CTD PMID:28534445 NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases activity
ISO Amphotericin B inhibits the reaction [[HIF1A protein binds to ARNT protein] which binds to EPO enhancer]; Amphotericin B inhibits the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]; Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein]
Amphotericin B results in decreased activity of HIF1A protein
CTD PMID:16189267 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor multiple interactions ISO Amphotericin B promotes the reaction [HIF1AN protein binds to and results in increased hydroxylation of and results in decreased activity of HIF1A protein] CTD PMID:16189267 NCBI chr 1:243,419,175...243,440,464
Ensembl chr 1:243,419,194...243,434,327
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Amphotericin B analog results in decreased expression of HILPDA mRNA CTD PMID:28534445 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 decreases expression ISO Amphotericin B analog results in decreased expression of HIPK1 mRNA CTD PMID:28534445 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA CTD PMID:36464106 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Amphotericin B analog results in increased expression of HMOX1 mRNA; Amphotericin B results in increased expression of HMOX1 mRNA CTD PMID:28534445 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hook1 hook microtubule-tethering protein 1 decreases expression ISO Amphotericin B analog results in decreased expression of HOOK1 mRNA CTD PMID:28534445 NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787
JBrowse link
G Hoxd3 homeo box D3 decreases expression ISO Amphotericin B analog results in decreased expression of HOXD3 mRNA CTD PMID:28534445 NCBI chr 3:59,638,708...59,650,282
Ensembl chr 3:59,638,708...59,650,282
JBrowse link
G Hoxd4 homeo box D4 decreases expression ISO Amphotericin B analog results in decreased expression of HOXD4 mRNA CTD PMID:28534445 NCBI chr 3:59,614,464...59,634,042
Ensembl chr 3:59,614,464...59,631,528
JBrowse link
G Hpx hemopexin increases expression ISO Amphotericin B analog results in increased expression of HPX mRNA CTD PMID:28534445 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO Amphotericin B analog results in decreased expression of HSPA1A mRNA CTD PMID:28534445 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B decreases expression ISO Amphotericin B analog results in decreased expression of HSPA1B mRNA CTD PMID:28534445 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO Amphotericin B analog results in decreased expression of HSPA2 mRNA CTD PMID:28534445 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO Amphotericin B results in increased expression of and results in increased secretion of HSPA8 protein CTD PMID:26259607 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb3 heat shock protein family B (small) member 3 increases expression ISO Amphotericin B analog results in increased expression of HSPB3 mRNA CTD PMID:28534445 NCBI chr 2:45,295,285...45,295,999
Ensembl chr 2:45,295,053...45,296,145
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A increases expression ISO Amphotericin B analog results in increased expression of HTR3A mRNA CTD PMID:28534445 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Amphotericin B analog results in increased expression of ICAM1 mRNA; Amphotericin B results in increased expression of ICAM1 mRNA CTD PMID:28534445 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO Amphotericin B analog results in decreased expression of ID2 mRNA CTD PMID:28534445 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Id4 inhibitor of DNA binding 4 decreases expression ISO Amphotericin B analog results in decreased expression of ID4 mRNA; Amphotericin B results in decreased expression of ID4 mRNA CTD PMID:28534445 NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Antimony Sodium Gluconate co-treated with Amphotericin B] results in increased expression of IFNG protein
Amphotericin B analog results in increased expression of IFNG mRNA
CTD PMID:17911647 PMID:28534445 PMID:29594315 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Amphotericin B results in increased expression of IFNGR1 CTD PMID:12803856 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression ISO Amphotericin B results in decreased expression of IGFBP5 mRNA CTD PMID:20849824 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of IL10 protein CTD PMID:17911647 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 increases expression ISO Amphotericin B analog results in increased expression of IL13RA2 mRNA CTD PMID:28534445 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Amphotericin B results in increased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1r2 interleukin 1 receptor type 2 decreases expression ISO Amphotericin B analog results in decreased expression of IL1R2 mRNA CTD PMID:28534445 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il1rapl2 interleukin 1 receptor accessory protein-like 2 increases expression ISO Amphotericin B analog results in increased expression of IL1RAPL2 mRNA CTD PMID:28534445 NCBI chr  X:100,961,509...102,271,753
Ensembl chr  X:100,961,812...102,271,753
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 increases expression ISO Amphotericin B analog results in increased expression of IL6 mRNA CTD PMID:28534445 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO Amphotericin B analog results in increased expression of INHBA mRNA CTD PMID:28534445 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Ino80b INO80 complex subunit B decreases expression ISO Amphotericin B analog results in decreased expression of INO80B mRNA CTD PMID:28534445 NCBI chr 4:115,627,907...115,631,069
Ensembl chr 4:115,627,908...115,631,456
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO Amphotericin B analog results in increased expression of INSIG1 mRNA; Amphotericin B results in increased expression of INSIG1 mRNA CTD PMID:28534445 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Irf5 interferon regulatory factor 5 increases expression ISO Amphotericin B analog results in increased expression of IRF5 mRNA CTD PMID:28534445 NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO Amphotericin B results in decreased expression of JAG1 mRNA CTD PMID:28534445 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
JBrowse link
G Kazn kazrin, periplakin interacting protein increases expression ISO Amphotericin B analog results in increased expression of KAZN mRNA CTD PMID:28534445 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Amphotericin B analog results in decreased expression of KCNB1 mRNA CTD PMID:28534445 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Kcnq4 potassium voltage-gated channel subfamily Q member 4 decreases expression ISO Amphotericin B results in decreased expression of KCNQ4 mRNA CTD PMID:20849824 NCBI chr 5:134,275,145...134,326,992
Ensembl chr 5:134,275,934...134,326,932
JBrowse link
G Klf12 KLF transcription factor 12 increases expression ISO Amphotericin B analog results in increased expression of KLF12 mRNA CTD PMID:28534445 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
JBrowse link
G Klf9 KLF transcription factor 9 decreases expression ISO Amphotericin B analog results in decreased expression of KLF9 mRNA CTD PMID:28534445 NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Klhl24 kelch-like family member 24 decreases expression ISO Amphotericin B analog results in decreased expression of KLHL24 mRNA CTD PMID:28534445 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
JBrowse link
G Klrb1a killer cell lectin like receptor B1A increases expression ISO Amphotericin B analog results in increased expression of KLRB1 mRNA CTD PMID:28534445 NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675
JBrowse link
G Kmo kynurenine 3-monooxygenase decreases expression ISO Amphotericin B analog results in decreased expression of KMO mRNA CTD PMID:28534445 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Lalba lactalbumin, alpha increases expression ISO Amphotericin B analog results in increased expression of LALBA mRNA CTD PMID:28534445 NCBI chr 7:129,625,531...129,628,034
Ensembl chr 7:129,625,535...129,628,061
JBrowse link
G Lcn2 lipocalin 2 decreases expression ISO Amphotericin B analog results in decreased expression of LCN2 mRNA CTD PMID:28534445 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA CTD PMID:36464106 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 increases expression ISO Amphotericin B analog results in increased expression of LDLRAD4 mRNA CTD PMID:28534445 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238
JBrowse link
G Lgals4 galectin 4 increases expression ISO Amphotericin B analog results in increased expression of LGALS4 mRNA CTD PMID:28534445 NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481
JBrowse link
G Limk1 LIM domain kinase 1 increases expression ISO Amphotericin B analog results in increased expression of LIMK1 mRNA CTD PMID:28534445 NCBI chr12:22,026,697...22,060,605
Ensembl chr12:22,026,672...22,060,606
JBrowse link
G Lpin1 lipin 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA CTD PMID:36464106 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lsg1 large 60S subunit nuclear export GTPase 1 decreases expression ISO Amphotericin B results in decreased expression of LSG1 mRNA CTD PMID:20849824 NCBI chr11:70,132,919...70,168,526
Ensembl chr11:70,143,847...70,168,518
JBrowse link
G Lyst lysosomal trafficking regulator increases expression ISO Amphotericin B analog results in increased expression of LYST mRNA CTD PMID:28534445 NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480
JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 increases expression ISO Amphotericin B analog results in increased expression of MADCAM1 mRNA CTD PMID:28534445 NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703
JBrowse link
G Maf MAF bZIP transcription factor decreases expression ISO Amphotericin B analog results in decreased expression of MAF mRNA CTD PMID:28534445 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Maoa monoamine oxidase A decreases expression ISO Amphotericin B analog results in decreased expression of MAOA mRNA CTD PMID:28534445 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO Amphotericin B results in increased expression of MAP1LC3B protein CTD PMID:23988732 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map3k19 mitogen-activated protein kinase kinase kinase 19 increases expression ISO Amphotericin B analog results in increased expression of MAP3K19 mRNA CTD PMID:28534445 NCBI chr13:39,300,150...39,343,502
Ensembl chr13:39,300,163...39,343,767
JBrowse link
G Mcm3ap minichromosome maintenance complex component 3 associated protein increases expression ISO Amphotericin B analog results in increased expression of MCM3AP mRNA CTD PMID:28534445 NCBI chr20:12,127,570...12,165,165
Ensembl chr20:12,127,570...12,165,165
JBrowse link
G Meak7 MTOR associated protein, eak-7 homolog increases expression ISO Amphotericin B analog results in increased expression of TLDC1 mRNA CTD PMID:28534445 NCBI chr19:47,813,899...47,836,830
Ensembl chr19:47,811,416...47,841,278
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression ISO Amphotericin B analog results in decreased expression of MEF2C mRNA CTD PMID:28534445 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mir106b microRNA 106b increases expression ISO Amphotericin B analog results in increased expression of MIR106B CTD PMID:28534445 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
JBrowse link
G Mir138-1 microRNA 138-1 increases expression ISO Amphotericin B results in increased expression of MIR138 CTD PMID:28534445 NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064
JBrowse link
G Mir17 microRNA 17 increases expression ISO Amphotericin B analog results in increased expression of MIR17 CTD PMID:28534445 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir181c microRNA 181c increases expression ISO Amphotericin B analog results in increased expression of MIR181C CTD PMID:28534445 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
JBrowse link
G Mir181d microRNA 181d decreases expression ISO Amphotericin B analog results in decreased expression of MIR181D CTD PMID:28534445 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
JBrowse link
G Mir423 microRNA 423 increases expression ISO Amphotericin B analog results in increased expression of MIR423; Amphotericin B results in increased expression of MIR423 CTD PMID:28534445 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir494 microRNA 494 decreases expression ISO Amphotericin B analog results in decreased expression of MIR494; Amphotericin B results in decreased expression of MIR494 CTD PMID:28534445 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mir99b microRNA 99b increases expression ISO Amphotericin B analog results in increased expression of MIR99B CTD PMID:28534445 NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090
JBrowse link
G Mirlet7g microRNA let-7g decreases expression ISO Amphotericin B analog results in decreased expression of MIRLET7G CTD PMID:28534445 NCBI chr 8:106,822,293...106,822,380
Ensembl chr 8:106,822,280...106,822,388
JBrowse link
G Mmp28 matrix metallopeptidase 28 decreases expression ISO Amphotericin B analog results in decreased expression of MMP28 mRNA CTD PMID:28534445 NCBI chr10:68,241,138...68,264,866
Ensembl chr10:68,241,138...68,264,866
JBrowse link
G Mphosph8 M-phase phosphoprotein 8 decreases expression ISO Amphotericin B analog results in decreased expression of MPHOSPH8 mRNA CTD PMID:28534445 NCBI chr15:30,800,546...30,828,415
Ensembl chr15:30,686,613...30,828,810
JBrowse link
G Mtf2 metal response element binding transcription factor 2 decreases expression ISO Amphotericin B analog results in decreased expression of MTF2 mRNA CTD PMID:28534445 NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming increases expression ISO Amphotericin B analog results in increased expression of MUC2 mRNA CTD PMID:28534445 NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756
JBrowse link
G Mx2 MX dynamin like GTPase 2 increases expression ISO Amphotericin B analog results in increased expression of MX2 mRNA CTD PMID:28534445 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
JBrowse link
G Myo15b myosin XVB increases expression ISO Amphotericin B analog results in increased expression of MYO15B mRNA CTD PMID:28534445 NCBI chr10:101,088,734...101,126,159
Ensembl chr10:101,104,209...101,125,693
JBrowse link
G Myo7a myosin VIIA increases expression ISO Amphotericin B analog results in increased expression of MYO7A mRNA CTD PMID:28534445 NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157
JBrowse link
G Nat8 N-acetyltransferase 8 decreases expression ISO Amphotericin B analog results in decreased expression of NAT8 mRNA CTD PMID:28534445 NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression ISO Amphotericin B analog results in decreased expression of NEDD9 mRNA CTD PMID:28534445 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
JBrowse link
G Nefl neurofilament light chain decreases expression ISO Amphotericin B analog results in decreased expression of NEFL mRNA CTD PMID:28534445 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nefm neurofilament medium chain decreases expression ISO Amphotericin B analog results in decreased expression of NEFM mRNA CTD PMID:28534445 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755
JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor decreases expression ISO Amphotericin B analog results in decreased expression of NF2 mRNA CTD PMID:28534445 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G Nol3 nucleolar protein 3 decreases expression ISO Amphotericin B analog results in decreased expression of NOL3 mRNA CTD PMID:28534445 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nprl2 NPR2-like, GATOR1 complex subunit decreases expression ISO Amphotericin B results in decreased expression of NPRL2 mRNA CTD PMID:20849824 NCBI chr 8:108,215,823...108,218,996
Ensembl chr 8:108,215,814...108,218,996
JBrowse link
G Nr2e1 nuclear receptor subfamily 2, group E, member 1 increases expression ISO Amphotericin B analog results in increased expression of NR2E1 mRNA CTD PMID:28534445 NCBI chr20:46,050,134...46,071,257
Ensembl chr20:46,050,414...46,073,949
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression ISO Amphotericin B analog results in decreased expression of NR2F1 mRNA CTD PMID:28534445 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123
JBrowse link
G Nt5c2 5'-nucleotidase, cytosolic II increases expression ISO Amphotericin B results in increased expression of NT5C2 mRNA CTD PMID:20849824 NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 decreases expression
increases expression
ISO Amphotericin B analog results in decreased expression of NTRK2 mRNA
Amphotericin B analog results in increased expression of NTRK2 mRNA
CTD PMID:28534445 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Or10j2 olfactory receptor family 10 subfamily J member 2 increases expression ISO Amphotericin B analog results in increased expression of OR10J1 mRNA CTD PMID:28534445 NCBI chr13:85,723,300...85,724,290
Ensembl chr13:85,719,234...85,724,767
JBrowse link
G Or2h2c olfactory receptor family 2 subfamily H member 2C increases expression ISO Amphotericin B analog results in increased expression of OR2H2 mRNA CTD PMID:28534445 NCBI chr20:1,398,964...1,399,902
Ensembl chr20:1,395,108...1,400,441
JBrowse link
G Ovol2 ovo-like zinc finger 2 increases expression ISO Amphotericin B analog results in increased expression of OVOL2 mRNA CTD PMID:28534445 NCBI chr 3:131,677,391...131,707,123
Ensembl chr 3:131,677,391...131,708,359
JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO Amphotericin B results in decreased expression of PAIP1 mRNA CTD PMID:20849824 NCBI chr 2:51,523,190...51,550,241
Ensembl chr 2:51,522,921...51,550,241
JBrowse link
G Pard3 par-3 family cell polarity regulator decreases expression ISO Amphotericin B results in decreased expression of PARD3 mRNA CTD PMID:20849824 NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778
JBrowse link
G Pard6b par-6 family cell polarity regulator beta increases expression ISO Amphotericin B analog results in increased expression of PARD6B mRNA CTD PMID:28534445 NCBI chr 3:156,790,540...156,811,620
Ensembl chr 3:156,790,540...156,811,622
JBrowse link
G Pde1a phosphodiesterase 1A decreases expression ISO Amphotericin B analog results in decreased expression of PDE1A mRNA CTD PMID:28534445 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874
JBrowse link
G Pde4d phosphodiesterase 4D decreases expression ISO Amphotericin B analog results in decreased expression of PDE4D mRNA CTD PMID:28534445 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein decreases expression ISO Amphotericin B analog results in decreased expression of PDE4DIP mRNA CTD PMID:28534445 NCBI chr 2:185,293,236...185,490,100
Ensembl chr 2:185,293,214...185,468,379
JBrowse link
G Pdlim7 PDZ and LIM domain 7 decreases expression ISO Amphotericin B analog results in decreased expression of PDLIM7 mRNA CTD PMID:28534445 NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 increases expression ISO Amphotericin B analog results in increased expression of PECAM1 mRNA CTD PMID:28534445 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO Amphotericin B inhibits the reaction [Oxygen deficiency results in increased expression of PGK1 mRNA] CTD PMID:16189267 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO Amphotericin B analog results in decreased expression of PIK3R1 mRNA CTD PMID:28534445 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pitx2 paired-like homeodomain 2 decreases expression ISO Amphotericin B analog results in decreased expression of PITX2 mRNA; Amphotericin B results in decreased expression of PITX2 mRNA CTD PMID:28534445 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293
JBrowse link
G Pklr pyruvate kinase L/R increases expression ISO Amphotericin B analog results in increased expression of PKLR mRNA CTD PMID:28534445 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pkp1 plakophilin 1 increases expression ISO Amphotericin B analog results in increased expression of PKP1 mRNA CTD PMID:28534445 NCBI chr13:47,309,607...47,357,432
Ensembl chr13:47,309,614...47,357,465
JBrowse link
G Pla2g2a phospholipase A2 group IIA increases expression ISO Amphotericin B analog results in increased expression of PLA2G2A mRNA CTD PMID:28534445 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Plcb1 phospholipase C beta 1 increases expression ISO Amphotericin B analog results in increased expression of PLCB1 mRNA CTD PMID:28534445 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Amphotericin B analog results in increased expression of PMAIP1 mRNA CTD PMID:28534445 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit increases expression ISO Amphotericin B analog results in increased expression of POLG mRNA; Amphotericin B results in increased expression of POLG mRNA CTD PMID:28534445 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
JBrowse link
G Polm DNA polymerase mu increases expression ISO Amphotericin B results in increased expression of POLM mRNA CTD PMID:20849824 NCBI chr14:80,707,075...80,716,677
Ensembl chr14:80,706,345...80,717,086
JBrowse link
G Ppl periplakin decreases expression ISO Amphotericin B analog results in decreased expression of PPL mRNA CTD PMID:28534445 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C decreases expression ISO Amphotericin B analog results in decreased expression of PPP1R3C mRNA CTD PMID:28534445 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO Amphotericin B analog results in decreased expression of PSAT1 mRNA CTD PMID:28534445 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 decreases expression ISO Amphotericin B analog results in decreased expression of PTPN22 mRNA CTD PMID:28534445 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link
G Ptprt protein tyrosine phosphatase, receptor type, T increases expression ISO Amphotericin B analog results in increased expression of PTPRT mRNA CTD PMID:28534445 NCBI chr 3:150,189,343...151,288,145
Ensembl chr 3:150,194,859...151,288,124
JBrowse link
G Rad54b RAD54 homolog B increases expression ISO Amphotericin B analog results in increased expression of RAD54B mRNA CTD PMID:28534445 NCBI chr 5:25,032,112...25,104,630
Ensembl chr 5:25,032,066...25,104,616
JBrowse link
G Ramp3 receptor activity modifying protein 3 increases expression ISO Amphotericin B analog results in increased expression of RAMP3 mRNA CTD PMID:28534445 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902
JBrowse link
G Rarres1 retinoic acid receptor responder 1 decreases expression ISO Amphotericin B analog results in decreased expression of RARRES1 mRNA CTD PMID:28534445 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression ISO Amphotericin B analog results in decreased expression of RASGRP1 mRNA CTD PMID:28534445 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Rbbp5 RB binding protein 5, histone lysine methyltransferase complex subunit decreases expression ISO Amphotericin B analog results in decreased expression of RBBP5 mRNA; Amphotericin B results in decreased expression of RBBP5 mRNA CTD PMID:28534445 NCBI chr13:43,912,254...43,939,107
Ensembl chr13:43,912,254...43,939,107
JBrowse link
G Rbm47 RNA binding motif protein 47 decreases expression ISO Amphotericin B analog results in decreased expression of RBM47 mRNA CTD PMID:28534445 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431
JBrowse link
G Rcan2 regulator of calcineurin 2 decreases expression ISO Amphotericin B analog results in decreased expression of RCAN2 mRNA CTD PMID:28534445 NCBI chr 9:16,959,478...17,174,823
Ensembl chr 9:16,959,480...17,174,856
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit decreases expression ISO Amphotericin B analog results in decreased expression of REL mRNA CTD PMID:28534445 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Reps2 RALBP1 associated Eps domain containing 2 decreases expression ISO Amphotericin B analog results in decreased expression of REPS2 mRNA CTD PMID:28534445 NCBI chr  X:32,049,455...32,322,317
Ensembl chr  X:32,049,399...32,317,414
JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression ISO Amphotericin B analog results in decreased expression of RGS2 mRNA; Amphotericin B results in decreased expression of RGS2 mRNA CTD PMID:28534445 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rhd Rh blood group, D antigen increases expression ISO Amphotericin B analog results in increased expression of RHD mRNA CTD PMID:28534445 NCBI chr 5:147,087,479...147,121,716
Ensembl chr 5:147,087,518...147,121,715
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 decreases expression ISO Amphotericin B analog results in decreased expression of FAM65B mRNA; Amphotericin B results in decreased expression of FAM65B mRNA CTD PMID:28534445 NCBI chr17:40,323,748...40,547,482
Ensembl chr17:40,323,867...40,548,092
JBrowse link
G Rmnd5a required for meiotic nuclear division 5 homolog A decreases expression ISO Amphotericin B analog results in decreased expression of RMND5A mRNA CTD PMID:28534445 NCBI chr 4:103,375,846...103,432,890
Ensembl chr 4:103,379,908...103,433,051
JBrowse link
G Rnase4 ribonuclease A family member 4 decreases expression ISO Amphotericin B analog results in decreased expression of RNASE4 mRNA CTD PMID:28534445 NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
JBrowse link
G Rnd3 Rho family GTPase 3 increases expression ISO Amphotericin B results in increased expression of RND3 mRNA CTD PMID:28534445 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
JBrowse link
G Rora RAR-related orphan receptor A decreases expression ISO Amphotericin B analog results in decreased expression of RORA mRNA CTD PMID:28534445 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rps8 ribosomal protein S8 increases expression ISO Amphotericin B analog results in increased expression of RPS8 mRNA CTD PMID:28534445 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator decreases expression ISO Amphotericin B analog results in decreased expression of RRAD mRNA CTD PMID:28534445 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
JBrowse link
G Rsl1d1 ribosomal L1 domain containing 1 decreases expression ISO Amphotericin B analog results in decreased expression of RSL1D1 mRNA CTD PMID:28534445 NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 increases expression ISO Amphotericin B results in increased expression of HLA-F mRNA CTD PMID:20849824 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Rtn1 reticulon 1 decreases expression ISO Amphotericin B analog results in decreased expression of RTN1 mRNA CTD PMID:28534445 NCBI chr 6:90,763,212...90,983,436
Ensembl chr 6:90,763,216...90,983,436
JBrowse link
G Runx3 RUNX family transcription factor 3 decreases expression ISO Amphotericin B results in decreased expression of RUNX3 mRNA CTD PMID:20849824 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156
JBrowse link
G Sap30 Sin3A associated protein 30 increases expression ISO Amphotericin B analog results in increased expression of SAP30 mRNA CTD PMID:28534445 NCBI chr16:32,747,777...32,753,114
Ensembl chr16:32,747,734...32,753,112
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha decreases expression ISO Amphotericin B analog results in decreased expression of SCNN1A mRNA CTD PMID:28534445 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
JBrowse link
G Serpina5 serpin family A member 5 decreases expression ISO Amphotericin B analog results in decreased expression of SERPINA5 mRNA CTD PMID:28534445 NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407
JBrowse link
G Serpinb3a serpin family B member 3A decreases expression ISO Amphotericin B analog results in decreased expression of SERPINB4 mRNA CTD PMID:28534445 NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 decreases expression ISO Amphotericin B results in decreased expression of SGK3 mRNA CTD PMID:28534445 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476
JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 increases expression ISO Amphotericin B analog results in increased expression of SIGLEC1 mRNA CTD PMID:28534445 NCBI chr 3:118,287,988...118,307,125
Ensembl chr 3:118,287,988...118,306,850
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Amphotericin B analog results in increased expression of SIK1 mRNA; Amphotericin B results in increased expression of SIK1 mRNA CTD PMID:28534445 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Slc16a6 solute carrier family 16, member 6 increases expression ISO Amphotericin B analog results in increased expression of SLC16A6 mRNA CTD PMID:28534445 NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779
JBrowse link
G Slc22a14 solute carrier family 22, member 14 increases expression ISO Amphotericin B analog results in increased expression of SLC22A14 mRNA CTD PMID:28534445 NCBI chr 8:118,894,537...118,916,416
Ensembl chr 8:118,895,259...118,908,255
JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SLC22A7 mRNA CTD PMID:36464106 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO Amphotericin B analog results in decreased expression of SLC27A2 mRNA CTD PMID:28534445 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression ISO Amphotericin B analog results in decreased expression of SLC2A5 mRNA CTD PMID:28534445 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc39a7 solute carrier family 39 member 7 decreases expression ISO Amphotericin B analog results in decreased expression of SLC39A7 mRNA CTD PMID:28534445 NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537
JBrowse link
G Slc5a1 solute carrier family 5 member 1 increases expression ISO Amphotericin B analog results in increased expression of SLC5A1 mRNA CTD PMID:28534445 NCBI chr14:77,553,990...77,618,589
Ensembl chr14:77,553,843...77,618,547
JBrowse link
G Slc6a6 solute carrier family 6 member 6 decreases expression ISO Amphotericin B analog results in decreased expression of SLC6A6 mRNA CTD PMID:28534445 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Slit1 slit guidance ligand 1 decreases expression ISO Amphotericin B results in decreased expression of SLIT1 mRNA CTD PMID:20849824 NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO Amphotericin B analog results in decreased expression of SORBS1 mRNA CTD PMID:28534445 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169
JBrowse link
G Sorl1 sortilin related receptor 1 decreases expression ISO Amphotericin B analog results in decreased expression of SORL1 mRNA CTD PMID:28534445 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513
JBrowse link
G Spag8 sperm associated antigen 8 decreases expression ISO Amphotericin B analog results in decreased expression of SPAG8 mRNA CTD PMID:28534445 NCBI chr 5:57,901,681...57,903,894
Ensembl chr 5:57,901,682...57,903,894
JBrowse link
G Spp1 secreted phosphoprotein 1 affects expression EXP Amphotericin B affects the expression of SPP1 mRNA CTD PMID:20623750 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 decreases expression ISO Amphotericin B analog results in decreased expression of SPRY1 mRNA CTD PMID:28534445 NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189
JBrowse link
G Sptbn5 spectrin, beta, non-erythrocytic 5 increases expression ISO Amphotericin B analog results in increased expression of SPTBN5 mRNA CTD PMID:28534445 NCBI chr 3:107,013,783...107,054,878
Ensembl chr 3:107,013,265...107,054,324
JBrowse link
G Sqle squalene epoxidase multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SQLE mRNA CTD PMID:36464106 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA]; [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA CTD PMID:36464106 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO [Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF2 mRNA CTD PMID:36464106 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Stc1 stanniocalcin 1 decreases expression ISO Amphotericin B analog results in decreased expression of STC1 mRNA CTD PMID:28534445 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
JBrowse link
G Stmn4 stathmin 4 increases expression ISO Amphotericin B analog results in increased expression of STMN4 mRNA CTD PMID:28534445 NCBI chr15:40,541,305...40,559,253
Ensembl chr15:40,541,357...40,559,253
JBrowse link
G Tac3 tachykinin precursor 3 increases expression ISO Amphotericin B analog results in increased expression of TAC3 mRNA CTD PMID:28534445 NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170
JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 decreases expression ISO Amphotericin B analog results in decreased expression of TACSTD2 mRNA CTD PMID:28534445 NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
JBrowse link
G Taf13 TATA-box binding protein associated factor 13 decreases expression ISO Amphotericin B analog results in decreased expression of TAF13 mRNA CTD PMID:28534445 NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878
JBrowse link
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor increases expression ISO Amphotericin B analog results in increased expression of TAL1 mRNA CTD PMID:28534445 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
JBrowse link
G Tcf20 transcription factor 20 increases expression ISO Amphotericin B analog results in increased expression of TCF20 mRNA CTD PMID:28534445 NCBI chr 7:113,953,449...114,104,166
Ensembl chr 7:113,954,089...114,051,839
JBrowse link
G Tenm1 teneurin transmembrane protein 1 decreases expression ISO Amphotericin B analog results in decreased expression of TENM1 mRNA CTD PMID:28534445 NCBI chr  X:121,400,466...122,289,877
Ensembl chr  X:121,403,649...122,290,207
JBrowse link
G Tent5a terminal nucleotidyltransferase 5A decreases expression ISO Amphotericin B analog results in decreased expression of FAM46A mRNA CTD PMID:28534445 NCBI chr 8:86,222,294...86,229,045
Ensembl chr 8:86,225,357...86,229,045
JBrowse link
G Tfdp2 transcription factor Dp-2 decreases expression ISO Amphotericin B analog results in decreased expression of TFDP2 mRNA; Amphotericin B results in decreased expression of TFDP2 mRNA CTD PMID:28534445 NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682
JBrowse link
G Tfec transcription factor EC decreases expression ISO Amphotericin B analog results in decreased expression of TFEC mRNA CTD PMID:28534445 NCBI chr 4:45,106,129...45,180,236
Ensembl chr 4:45,107,641...45,180,236
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO Amphotericin B analog results in increased expression of TFF1 mRNA CTD PMID:28534445 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Antimony Sodium Gluconate co-treated with Amphotericin B] results in decreased expression of TGFB1 protein CTD PMID:17911647 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Themis2 thymocyte selection associated family member 2 decreases expression ISO Amphotericin B analog results in decreased expression of THEMIS2 mRNA CTD PMID:28534445 NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400
JBrowse link
G Tmcc1 transmembrane and coiled-coil domain family 1 decreases expression ISO Amphotericin B analog results in decreased expression of TMCC1 mRNA CTD PMID:28534445 NCBI chr 4:149,069,252...149,239,585
Ensembl chr 4:149,069,260...149,239,620
JBrowse link
G Tmem140 transmembrane protein 140 decreases expression ISO Amphotericin B analog results in decreased expression of TMEM140 mRNA CTD PMID:28534445 NCBI chr 4:63,536,477...63,547,478
Ensembl chr 4:63,536,168...63,548,455
JBrowse link
G Tmem151b transmembrane protein 151B increases expression ISO Amphotericin B results in increased expression of TMEM151B mRNA CTD PMID:28534445 NCBI chr 9:15,456,446...15,464,289
Ensembl chr 9:15,455,801...15,464,302
JBrowse link
G Tmem176b transmembrane protein 176B decreases expression ISO Amphotericin B analog results in decreased expression of TMEM176B mRNA CTD PMID:28534445 NCBI chr 4:77,766,928...77,774,740
Ensembl chr 4:77,766,928...77,774,384
JBrowse link
G Tmem255a transmembrane protein 255A decreases expression ISO Amphotericin B analog results in decreased expression of TMEM255A mRNA CTD PMID:28534445 NCBI chr  X:116,970,793...117,035,008
Ensembl chr  X:116,970,695...117,035,008
JBrowse link
G Tmem45a transmembrane protein 45A decreases expression ISO Amphotericin B analog results in decreased expression of TMEM45A mRNA CTD PMID:28534445 NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526
JBrowse link
G Tnf tumor necrosis factor increases expression EXP Amphotericin B results in increased expression of TNF mRNA CTD PMID:20623750 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Amphotericin B analog results in increased expression of TNFAIP3 mRNA CTD PMID:28534445 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfsf4 TNF superfamily member 4 decreases expression ISO Amphotericin B analog results in decreased expression of TNFSF4 mRNA CTD PMID:28534445 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tox3 TOX high mobility group box family member 3 decreases expression ISO Amphotericin B analog results in decreased expression of TOX3 mRNA CTD PMID:28534445 NCBI chr19:16,648,338...16,757,151
Ensembl chr19:16,648,342...16,757,148
JBrowse link
G Tp63 tumor protein p63 increases expression ISO Amphotericin B analog results in increased expression of TP63 mRNA CTD PMID:28534445 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 decreases expression ISO Amphotericin B analog results in decreased expression of TREM1 mRNA CTD PMID:28534445 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203
JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 decreases expression ISO Amphotericin B analog results in decreased expression of TRPM3 mRNA CTD PMID:28534445 NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 increases expression ISO Amphotericin B analog results in increased expression of TRPM6 mRNA CTD PMID:28534445 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 decreases expression ISO Amphotericin B analog results in decreased expression of TRPS1 mRNA CTD PMID:28534445 NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
JBrowse link
G Tssk2 testis-specific serine kinase 2 increases expression ISO Amphotericin B analog results in increased expression of TSSK2 mRNA CTD PMID:28534445 NCBI chr11:83,086,578...83,087,933 JBrowse link
G Txnip thioredoxin interacting protein decreases expression ISO Amphotericin B analog results in decreased expression of TXNIP mRNA CTD PMID:28534445 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ube2d2b ubiquitin-conjugating enzyme E2D 2B increases expression ISO Amphotericin B analog results in increased expression of UBE2D4 mRNA CTD PMID:28534445 NCBI chr14:1,915,999...1,917,473
Ensembl chr14:1,916,845...1,917,416
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects expression EXP Amphotericin B affects the expression of UGT1A9 mRNA CTD PMID:20623750 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Usp2 ubiquitin specific peptidase 2 increases expression ISO Amphotericin B analog results in increased expression of USP2 mRNA CTD PMID:28534445 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Usp36 ubiquitin specific peptidase 36 increases expression ISO Amphotericin B results in increased expression of USP36 mRNA CTD PMID:20849824 NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877
JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 decreases expression ISO Amphotericin B analog results in decreased expression of VAV3 mRNA; Amphotericin B results in decreased expression of VAV3 mRNA CTD PMID:28534445 NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321
JBrowse link
G Vgll1 vestigial-like family member 1 increases expression ISO Amphotericin B analog results in increased expression of VGLL1 mRNA CTD PMID:28534445 NCBI chr  X:134,979,657...134,996,007 JBrowse link
G Vnn1 vanin 1 decreases expression ISO Amphotericin B analog results in decreased expression of VNN1 mRNA CTD PMID:28534445 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 increases expression ISO Amphotericin B analog results in increased expression of XPNPEP2 mRNA CTD PMID:28534445 NCBI chr  X:127,287,765...127,317,036
Ensembl chr  X:127,287,979...127,317,223
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression ISO Amphotericin B analog results in decreased expression of ZBTB16 mRNA CTD PMID:28534445 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zfp236 zinc finger protein 236 increases expression ISO Amphotericin B analog results in increased expression of ZNF236 mRNA CTD PMID:28534445 NCBI chr18:75,976,478...76,072,428
Ensembl chr18:75,978,231...76,073,737
JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 decreases expression ISO Amphotericin B analog results in decreased expression of ZFP36L2 mRNA CTD PMID:28534445 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064
JBrowse link
G Zfp652 zinc finger protein 652 decreases expression ISO Amphotericin B results in decreased expression of ZNF652 mRNA CTD PMID:28534445 NCBI chr10:80,626,555...80,706,397
Ensembl chr10:80,649,400...80,698,674
JBrowse link
G Zfx zinc finger protein X-linked decreases expression ISO Amphotericin B results in decreased expression of ZFX mRNA CTD PMID:28534445 NCBI chr  X:58,804,690...58,853,155
Ensembl chr  X:58,804,691...58,853,265
JBrowse link
G Zmat4 zinc finger, matrin type 4 increases expression ISO Amphotericin B analog results in increased expression of ZMAT4 mRNA CTD PMID:28534445 NCBI chr16:67,969,410...68,361,377
Ensembl chr16:67,969,416...68,361,202
JBrowse link
amphotericin B methyl ester term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO methylamphotericin B results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO methylamphotericin B results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO methylamphotericin B results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO methylamphotericin B results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
caspofungin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase decreases activity ISO caspofungin results in decreased activity of HNMT protein CTD PMID:12921242 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
everolimus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Everolimus results in decreased activity of ABCB11 protein CTD PMID:23956101 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects stability
affects response to substance
multiple interactions
ISO ABCB1A protein affects the stability of Everolimus
ABCB1 polymorphism affects the susceptibility to Everolimus
bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1A protein affects the stability of Everolimus]; Everolimus inhibits the reaction [ABCB1A protein affects the metabolism of irinotecan]
CTD PMID:24727322 PMID:27169792 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects stability
multiple interactions
ISO ABCB1B protein affects the stability of Everolimus
bis(4-nitrophenyl)phosphate inhibits the reaction [ABCB1B protein affects the stability of Everolimus]; Everolimus inhibits the reaction [ABCB1B protein affects the metabolism of irinotecan]
CTD PMID:24727322 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects stability
multiple interactions
ISO ABCG2 protein affects the stability of Everolimus
bis(4-nitrophenyl)phosphate inhibits the reaction [ABCG2 protein affects the stability of Everolimus]; Everolimus inhibits the reaction [ABCG2 protein affects the metabolism of irinotecan]
CTD PMID:24727322 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
decreases phosphorylation
ISO Everolimus results in increased phosphorylation of AKT1 protein
Everolimus results in decreased phosphorylation of AKT1 protein
CTD PMID:16033851 PMID:22885370 PMID:23300809 PMID:28711525 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression
multiple interactions
ISO Everolimus results in decreased expression of BIRC5 protein
Everolimus promotes the reaction [platycodin D results in decreased expression of BIRC5 protein]; navitoclax promotes the reaction [Everolimus results in decreased expression of BIRC5 protein]; platycodin D promotes the reaction [Everolimus results in decreased expression of BIRC5 protein]
CTD PMID:21601561 PMID:28711525 PMID:28947240 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Brd4 bromodomain containing 4 multiple interactions ISO [MYC protein results in decreased susceptibility to Everolimus] promotes the reaction [BRD4 protein binds to MYC gene] CTD PMID:25537515 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Casp3 caspase 3 increases cleavage ISO Everolimus results in increased cleavage of CASP3 protein CTD PMID:15940265 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Everolimus results in decreased expression of CCNA2 protein CTD PMID:16856892 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO Everolimus results in decreased expression of CCND1 protein
[letrozole co-treated with Everolimus] results in decreased expression of CCND1 protein
CTD PMID:16033851 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 multiple interactions
decreases expression
ISO [letrozole co-treated with Everolimus] results in decreased expression of CCND2 protein
Everolimus results in decreased expression of CCND2 protein
CTD PMID:16033851 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Everolimus results in decreased expression of CCND3 protein CTD PMID:16856892 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Everolimus results in increased expression of CDH1 protein CTD PMID:28258630 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Ces1d carboxylesterase 1D decreases activity ISO Everolimus results in decreased activity of CES1 protein CTD PMID:24727322 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Ces2h carboxylesterase 2H decreases activity ISO Everolimus results in decreased activity of CES2 protein CTD PMID:24727322 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Egfr epidermal growth factor receptor increases expression
multiple interactions
ISO Everolimus results in increased expression of EGFR mRNA; Everolimus results in increased expression of EGFR protein
platycodin D inhibits the reaction [Everolimus results in increased expression of EGFR protein]
CTD PMID:28711525 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases phosphorylation
multiple interactions
ISO Everolimus results in increased phosphorylation of EIF4E protein
Everolimus inhibits the reaction [Estradiol results in decreased phosphorylation of EIF4E protein]
CTD PMID:16033851 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
ISO [letrozole co-treated with Everolimus] results in increased phosphorylation of and results in decreased activity of EIF4EBP1 protein; Everolimus inhibits the reaction [Estradiol results in increased phosphorylation of and results in decreased activity of EIF4EBP1 protein]; Everolimus promotes the reaction [platycodin D results in decreased phosphorylation of EIF4EBP1 protein]; Everolimus results in increased phosphorylation of and results in decreased activity of EIF4EBP1 protein; platycodin D promotes the reaction [Everolimus results in decreased phosphorylation of EIF4EBP1 protein] CTD PMID:16033851 PMID:16856892 PMID:16951235 PMID:21372221 PMID:28711525 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 multiple interactions ISO Everolimus inhibits the reaction [Estradiol results in increased phosphorylation of EIF4G1 protein] CTD PMID:16033851 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Everolimus promotes the reaction [TNF protein results in increased expression of F3 protein] CTD PMID:19567381 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions
increases expression
ISO platycodin D inhibits the reaction [Everolimus results in increased expression of IGF1R protein]
Everolimus results in increased expression of IGF1R mRNA; Everolimus results in increased expression of IGF1R protein
CTD PMID:28711525 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO Everolimus promotes the reaction [Tretinoin results in increased expression of ITGAM protein] CTD PMID:29743969 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO Everolimus promotes the reaction [N-((1R,2S)-2-hydroxy-1-hydroxymethyl-2-(2-tridecyl-1-cyclopropenyl)ethyl)octanamide results in increased expression of and results in increased lipidation of MAP1LC3B protein] CTD PMID:32397857 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO Everolimus inhibits the reaction [4-cresol results in increased expression of MMP9 protein] CTD PMID:30910523 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases activity
ISO
EXP
[Everolimus co-treated with Y 27632] inhibits the reaction [4-cresol results in increased phosphorylation of MTOR protein]; [Letrozole co-treated with Everolimus] inhibits the reaction [Androstenedione affects the activity of MTOR protein]; Everolimus inhibits the reaction [4-cresol results in increased phosphorylation of MTOR protein]; Everolimus inhibits the reaction [Androstenedione affects the activity of MTOR protein]; Everolimus inhibits the reaction [Estradiol affects the activity of MTOR protein]; Everolimus inhibits the reaction [MTOR results in decreased susceptibility to Trabectedin]
Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]
Everolimus results in decreased activity of MTOR; Everolimus results in decreased activity of MTOR protein
CTD PMID:16033851 PMID:20890178 PMID:21622721 PMID:24989011 PMID:30910523 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance
increases expression
ISO [MYC protein results in decreased susceptibility to Everolimus] promotes the reaction [BRD4 protein binds to MYC gene]
Everolimus results in increased expression of MYC protein
CTD PMID:25537515 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ngf nerve growth factor multiple interactions EXP Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of MTOR protein]]; Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]] CTD PMID:24989011 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases expression
ISO Aspirin inhibits the reaction [Everolimus results in decreased expression of NOS3 protein]; cilostazol inhibits the reaction [Everolimus results in decreased expression of NOS3 protein] CTD PMID:19520256 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases activity ISO Everolimus results in decreased activity of NR1I3 protein CTD PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [navitoclax co-treated with Everolimus] results in increased cleavage of PARP1 protein CTD PMID:28947240 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Everolimus results in increased expression of PTGS2 mRNA; Everolimus results in increased expression of PTGS2 protein CTD PMID:15937522 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO Everolimus results in decreased expression of PTK2 protein modified form CTD PMID:28258630 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
decreases phosphorylation
ISO [letrozole co-treated with Everolimus] results in decreased phosphorylation of and affects the activity of RB1 protein; Everolimus results in decreased phosphorylation of and affects the activity of RB1 protein
Everolimus results in decreased phosphorylation of RB1 protein
CTD PMID:16033851 PMID:16856892 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rhoa ras homolog family member A decreases expression
multiple interactions
ISO Everolimus results in decreased expression of RHOA protein
[Everolimus co-treated with Y 27632] inhibits the reaction [4-cresol results in increased expression of RHOA protein]
CTD PMID:28258630 PMID:30910523 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
JBrowse link
G Rps6 ribosomal protein S6 multiple interactions
decreases phosphorylation
ISO [letrozole co-treated with Everolimus] results in decreased phosphorylation of RPS6 protein; Everolimus inhibits the reaction [Estradiol results in increased phosphorylation of RPS6 protein]
Everolimus results in decreased phosphorylation of RPS6 protein
CTD PMID:16033851 PMID:21372221 PMID:22885370 PMID:23151917 PMID:23300809 More... NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP
ISO
Everolimus inhibits the reaction [rhodioloside inhibits the reaction [[cobaltous chloride co-treated with NGF protein] results in decreased phosphorylation of RPS6KB1 protein]]
Everolimus inhibits the reaction [Estradiol results in increased phosphorylation of RPS6KB1 protein]; Everolimus inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]
CTD PMID:16033851 PMID:19567381 PMID:24989011 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression
ISO Aspirin inhibits the reaction [Everolimus results in decreased expression of SIRT1 protein]; cilostazol inhibits the reaction [Everolimus results in decreased expression of SIRT1 protein] CTD PMID:19520256 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase decreases expression ISO Everolimus results in decreased expression of SRC protein modified form CTD PMID:28258630 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Everolimus inhibits the reaction [TNF protein results in increased phosphorylation of RPS6KB1 protein]; Everolimus promotes the reaction [TNF protein results in increased expression of F3 protein] CTD PMID:19567381 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vim vimentin decreases expression ISO Everolimus results in decreased expression of VIM protein CTD PMID:28258630 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
fumagillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of BCL2 mRNA] CTD PMID:15682466 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Metap1 methionyl aminopeptidase 1 decreases activity
multiple interactions
ISO fumagillin results in decreased activity of METAP1 protein
[fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein
CTD PMID:14534293 NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434
JBrowse link
G Metap2 methionyl aminopeptidase 2 multiple interactions
decreases activity
EXP
ISO
fumagillin promotes the reaction [Diethylnitrosamine results in increased expression of METAP2 mRNA]
fumagillin results in decreased activity of METAP2 protein
[fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein
CTD PMID:14534293 PMID:15516829 PMID:15682466 NCBI chr 7:28,412,429...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions EXP fumagillin inhibits the reaction [Diethylnitrosamine results in increased activity of TERT protein]; fumagillin inhibits the reaction [Diethylnitrosamine results in increased expression of TERT mRNA] CTD PMID:15682466 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma multiple interactions ISO [fumagillin results in decreased activity of [METAP1 protein co-treated with METAP2 protein]] which results in decreased metabolism of YWHAG protein CTD PMID:14534293 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
griseofulvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Griseofulvin results in increased expression of ABCB1A mRNA CTD PMID:8707270 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression ISO Griseofulvin results in increased expression of ABCB4 mRNA CTD PMID:8707270 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression EXP
ISO
Griseofulvin results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression ISO Griseofulvin results in decreased expression of ADRB3 mRNA CTD PMID:12735108 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 affects expression
multiple interactions
increases activity
increases expression
ISO Griseofulvin affects the expression of ALAS1 mRNA
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; [Ascorbic Acid co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Ascorbic Acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Melatonin inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]
Griseofulvin results in increased expression of ALAS1 mRNA
CTD PMID:10215191 PMID:12735108 PMID:15793285 PMID:24523661 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Anxa2 annexin A2 increases expression ISO Griseofulvin results in increased expression of ANXA2 mRNA CTD PMID:12735108 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Anxa3 annexin A3 affects expression ISO Griseofulvin affects the expression of ANXA3 mRNA CTD PMID:12735108 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Anxa5 annexin A5 increases expression ISO Griseofulvin results in increased expression of ANXA5 mRNA CTD PMID:12735108 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Anxa6 annexin A6 increases expression ISO Griseofulvin results in increased expression of ANXA6 mRNA CTD PMID:12735108 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
JBrowse link
G Areg amphiregulin increases expression ISO Griseofulvin results in increased expression of AREG protein CTD PMID:19267999 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Btc betacellulin increases expression ISO Griseofulvin results in increased expression of BTC protein CTD PMID:19267999 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
ISO Griseofulvin results in increased activity of CASP3 protein
Griseofulvin results in increased cleavage of CASP3 protein
CTD PMID:23329179 PMID:25412316 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO Griseofulvin results in increased activity of CASP9 protein CTD PMID:23329179 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression ISO Griseofulvin affects the expression of CBR1 mRNA CTD PMID:12735108 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cd14 CD14 molecule affects expression ISO Griseofulvin affects the expression of CD14 mRNA CTD PMID:12735108 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cd24 CD24 molecule affects expression ISO Griseofulvin affects the expression of CD24A mRNA CTD PMID:12735108 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Griseofulvin results in increased expression of COL1A1 mRNA CTD PMID:12735108 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression ISO Griseofulvin results in increased expression of COL3A1 mRNA CTD PMID:12735108 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col4a1 collagen type IV alpha 1 chain affects expression ISO Griseofulvin affects the expression of COL4A1 mRNA CTD PMID:12735108 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Cstb cystatin B increases expression ISO Griseofulvin results in increased expression of CSTB mRNA CTD PMID:12735108 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects expression
multiple interactions
ISO Griseofulvin affects the expression of CYP1A2 mRNA
Griseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]
CTD PMID:9029748 PMID:12735108 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 affects expression ISO Griseofulvin affects the expression of CYP2A4 mRNA CTD PMID:12735108 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression ISO Griseofulvin affects the expression of CYP2B13 mRNA CTD PMID:12735108 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression ISO Griseofulvin affects the expression of CYP2B10 mRNA CTD PMID:12735108 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 affects expression ISO Griseofulvin affects the expression of CYP2C29 mRNA CTD PMID:12735108 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Griseofulvin results in increased expression of CYP3A4 mRNA; Griseofulvin results in increased expression of CYP3A4 protein CTD PMID:18505790 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Griseofulvin results in decreased expression of CYP7B1 mRNA CTD PMID:12735108 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Eln elastin affects expression ISO Griseofulvin affects the expression of ELN mRNA CTD PMID:12735108 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Ereg epiregulin increases expression ISO Griseofulvin results in increased expression of EREG protein CTD PMID:19267999 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO Griseofulvin results in decreased expression of FABP1 mRNA CTD PMID:12735108 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fech ferrochelatase decreases activity
increases expression
multiple interactions
ISO Griseofulvin results in decreased activity of FECH protein
Griseofulvin results in increased expression of FECH mRNA
[Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron; heme arginate inhibits the reaction [[Griseofulvin results in decreased activity of FECH protein] which results in decreased uptake of Iron]
CTD PMID:10215191 PMID:15078340 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fstl1 follistatin-like 1 affects expression ISO Griseofulvin affects the expression of FSTL1 mRNA CTD PMID:12735108 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G G0s2 G0/G1switch 2 decreases expression ISO Griseofulvin results in decreased expression of G0S2 mRNA CTD PMID:12735108 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta affects expression ISO Griseofulvin affects the expression of GADD45B mRNA CTD PMID:12735108 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
ISO Griseofulvin results in increased expression of and results in increased localization of GJA1 protein
Griseofulvin results in increased expression of GJA1 mRNA
CTD PMID:23329179 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gstm2 glutathione S-transferase mu 2 affects expression ISO Griseofulvin affects the expression of GSTM2 mRNA CTD PMID:12735108 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Hmox1 heme oxygenase 1 increases activity
increases expression
ISO Griseofulvin results in increased activity of HMOX1 protein
Griseofulvin results in increased expression of HMOX1 mRNA; Griseofulvin results in increased expression of HMOX1 protein
CTD PMID:10215191 PMID:15793285 PMID:16309571 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ier3 immediate early response 3 affects expression ISO Griseofulvin affects the expression of IER3 mRNA CTD PMID:12735108 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO Griseofulvin results in decreased expression of IGF1 mRNA CTD PMID:12735108 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression ISO Griseofulvin results in decreased expression of IGFALS mRNA CTD PMID:12735108 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression ISO Griseofulvin affects the expression of IGFBP2 mRNA CTD PMID:12735108 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO Griseofulvin inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein] CTD PMID:11367519 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Inhbc inhibin subunit beta C decreases expression ISO Griseofulvin results in decreased expression of INHBC mRNA CTD PMID:12735108 NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 affects expression ISO Griseofulvin affects the expression of IQGAP1 mRNA CTD PMID:12735108 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Itgb2 integrin subunit beta 2 affects expression ISO Griseofulvin affects the expression of ITGB2 mRNA CTD PMID:12735108 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Krt18 keratin 18 multiple interactions
increases expression
decreases response to substance
ISO Griseofulvin promotes the reaction [KRT18 protein binds to KRT18 protein]
Griseofulvin results in increased expression of KRT18 mRNA; Griseofulvin results in increased expression of KRT18 protein
KRT18 protein results in decreased susceptibility to Griseofulvin
CTD PMID:7504119 PMID:8770877 PMID:10952237 PMID:12388748 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt8 keratin 8 increases expression
increases phosphorylation
ISO Griseofulvin results in increased expression of KRT8 mRNA; Griseofulvin results in increased expression of KRT8 protein
Griseofulvin results in increased phosphorylation of KRT8 protein
CTD PMID:7504119 PMID:10952237 PMID:12735108 PMID:20643122 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO Griseofulvin results in decreased expression of LAMB1 protein CTD PMID:1573853 NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
JBrowse link
G Lamb2 laminin subunit beta 2 decreases expression
increases expression
ISO Griseofulvin results in decreased expression of LAMB2 protein
Griseofulvin results in increased expression of LAMB2 mRNA
CTD PMID:1573853 NCBI chr 8:109,178,367...109,190,552
Ensembl chr 8:109,178,409...109,190,549
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 affects expression ISO Griseofulvin affects the expression of LILRB4 mRNA CTD PMID:12735108 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
JBrowse link
G Lpl lipoprotein lipase affects expression ISO Griseofulvin affects the expression of LPL mRNA CTD PMID:12735108 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO Griseofulvin results in increased expression of LY6D mRNA CTD PMID:12735108 NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733
JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO Griseofulvin results in increased expression of MAPT mRNA; Griseofulvin results in increased expression of MAPT mRNA alternative form; Griseofulvin results in increased expression of MAPT protein CTD PMID:10051481 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Npdc1 neural proliferation, differentiation and control, 1 affects expression ISO Griseofulvin affects the expression of NPDC1 mRNA CTD PMID:12735108 NCBI chr 3:8,220,446...8,226,446
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Griseofulvin results in increased expression of NQO1 mRNA CTD PMID:12735108 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Griseofulvin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 affects expression ISO Griseofulvin affects the expression of PAPSS2 mRNA CTD PMID:12735108 NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331
JBrowse link
G Pf4 platelet factor 4 affects expression ISO Griseofulvin affects the expression of PF4 mRNA CTD PMID:12735108 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Por cytochrome p450 oxidoreductase affects expression ISO Griseofulvin affects the expression of POR mRNA CTD PMID:12735108 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO Griseofulvin results in decreased expression of PPARA mRNA CTD PMID:9548566 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO Griseofulvin results in increased expression of PPARD mRNA CTD PMID:9548566 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Griseofulvin results in increased expression of PPARG mRNA CTD PMID:9548566 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppl periplakin affects expression ISO Griseofulvin affects the expression of PPL mRNA CTD PMID:12735108 NCBI chr10:10,450,919...10,496,575
Ensembl chr10:10,450,919...10,496,575
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO Griseofulvin results in increased expression of RARA mRNA CTD PMID:9548566 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO Griseofulvin results in increased expression of RARB mRNA CTD PMID:9548566 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarg retinoic acid receptor, gamma increases expression ISO Griseofulvin results in increased expression of RARG mRNA CTD PMID:9548566 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO Griseofulvin results in decreased expression of RXRA mRNA CTD PMID:9548566 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrg retinoid X receptor gamma decreases expression ISO Griseofulvin results in decreased expression of RXRG mRNA CTD PMID:9548566 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO Griseofulvin results in increased expression of S100A6 mRNA CTD PMID:12735108 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 affects expression ISO Griseofulvin affects the expression of SCD2 mRNA CTD PMID:12735108 NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
JBrowse link
G Sele selectin E multiple interactions ISO Griseofulvin inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:11367519 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Sell selectin L decreases expression ISO Griseofulvin results in decreased expression of SELL protein CTD PMID:11367519 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Soat1 sterol O-acyltransferase 1 affects expression ISO Griseofulvin affects the expression of SOAT1 mRNA CTD PMID:12735108 NCBI chr13:68,552,274...68,597,529
Ensembl chr13:68,552,317...68,597,494
JBrowse link
G Spp1 secreted phosphoprotein 1 affects expression ISO Griseofulvin affects the expression of SPP1 mRNA CTD PMID:12735108 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tgm2 transglutaminase 2 affects expression ISO Griseofulvin affects the expression of TGM2 mRNA CTD PMID:12735108 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Tm4sf4 transmembrane 4 L six family member 4 affects expression ISO Griseofulvin affects the expression of TM4SF4 mRNA CTD PMID:12735108 NCBI chr 2:141,570,321...141,621,263
Ensembl chr 2:141,481,902...141,621,200
JBrowse link
G Tmsb10 thymosin, beta 10 affects expression ISO Griseofulvin affects the expression of TMSB10 mRNA CTD PMID:12735108 NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
JBrowse link
G Tmsb4x thymosin beta 4, X-linked affects expression ISO Griseofulvin affects the expression of TMSB4X mRNA CTD PMID:12735108 NCBI chr  X:27,144,666...27,146,667
Ensembl chr  X:27,128,610...27,146,667
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Griseofulvin inhibits the reaction [TNF protein results in increased expression of SELE protein]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]] CTD PMID:11154858 PMID:11367519 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase affects expression ISO Griseofulvin affects the expression of UGDH mRNA CTD PMID:12735108 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression ISO Griseofulvin affects the expression of UGT1A1 mRNA CTD PMID:12735108 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 affects expression
multiple interactions
ISO Griseofulvin affects the expression of VCAM1 mRNA
Griseofulvin inhibits the reaction [IL1A protein results in increased expression of VCAM1 protein]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Paclitaxel inhibits the reaction [Griseofulvin inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]]
CTD PMID:11154858 PMID:11367519 PMID:12735108 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcl vinculin affects localization ISO Griseofulvin affects the localization of VCL protein CTD PMID:25412316 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Wnt3a Wnt family member 3A affects expression ISO Griseofulvin affects the expression of WNT3A mRNA CTD PMID:12735108 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324
JBrowse link
G Ybx3 Y box binding protein 3 affects expression ISO Griseofulvin affects the expression of YBX3 mRNA CTD PMID:12735108 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
JBrowse link
natamycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin increases expression ISO Natamycin results in increased expression of CLU mRNA CTD PMID:22863853 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cp ceruloplasmin increases expression ISO Natamycin results in increased expression of CP mRNA CTD PMID:22863853 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Fga fibrinogen alpha chain increases expression ISO Natamycin results in increased expression of FGA mRNA CTD PMID:22863853 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO Natamycin results in increased expression of FGG mRNA CTD PMID:22863853 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Natamycin results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Krt19 keratin 19 increases expression ISO Natamycin results in increased expression of KRT19 mRNA CTD PMID:22863853 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Natamycin results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Natamycin results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Natamycin results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
nystatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO Nystatin inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein] CTD PMID:12614848 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Nystatin inhibits the reaction [resveratrol affects the localization of CASP8 protein] CTD PMID:12902349 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO Nystatin inhibits the reaction [Quercetin affects the localization of CAV1 protein] CTD PMID:17876056 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cd40 CD40 molecule increases expression ISO Nystatin results in increased expression of CD40 protein CTD PMID:16374455 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd80 Cd80 molecule increases expression ISO Nystatin results in increased expression of CD80 protein CTD PMID:16374455 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule increases expression ISO Nystatin results in increased expression of CD86 protein CTD PMID:16374455 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Clu clusterin increases expression ISO Nystatin results in increased expression of CLU mRNA CTD PMID:22863853 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cp ceruloplasmin increases expression ISO Nystatin results in increased expression of CP mRNA CTD PMID:22863853 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO Nystatin inhibits the reaction [resveratrol affects the localization of FADD protein] CTD PMID:12902349 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Nystatin inhibits the reaction [resveratrol affects the localization of FAS protein] CTD PMID:12902349 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fga fibrinogen alpha chain increases expression ISO Nystatin results in increased expression of FGA mRNA CTD PMID:22863853 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgg fibrinogen gamma chain increases expression ISO Nystatin results in increased expression of FGG mRNA CTD PMID:22863853 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Nystatin results in increased expression of HAVCR1 mRNA CTD PMID:22863853 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Nystatin results in increased expression of ICAM1 protein CTD PMID:16374455 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Nystatin results in increased expression of IL1B mRNA; Nystatin results in increased expression of IL1B protein CTD PMID:16374455 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression ISO Nystatin results in increased expression of IL6 protein CTD PMID:16374455 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Krt18 keratin 18 increases expression ISO Nystatin results in increased expression of KRT18 mRNA CTD PMID:22863853 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt19 keratin 19 increases expression ISO Nystatin results in increased expression of KRT19 mRNA CTD PMID:22863853 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
JBrowse link
G Krt8 keratin 8 increases expression ISO Nystatin results in increased expression of KRT8 mRNA CTD PMID:22863853 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Nystatin results in increased expression of LCN2 mRNA CTD PMID:22863853 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP Nystatin inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Estriol results in increased phosphorylation of MAPK1 protein]; Nystatin inhibits the reaction [Estrone results in increased phosphorylation of MAPK1 protein] CTD PMID:15072920 PMID:22230296 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP Nystatin inhibits the reaction [4-ethylphenol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [4-propylphenol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Diethylstilbestrol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Nystatin inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Estriol results in increased phosphorylation of MAPK3 protein]; Nystatin inhibits the reaction [Estrone results in increased phosphorylation of MAPK3 protein] CTD PMID:15072920 PMID:22230296 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Prnp prion protein multiple interactions ISO Nystatin inhibits the reaction [Copper Sulfate results in increased uptake of and affects the localization of PRNP protein] CTD PMID:11994310 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit increases activity ISO Nystatin results in increased activity of REL protein CTD PMID:16374455 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity ISO Nystatin results in increased activity of RELA protein CTD PMID:16374455 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Nystatin results in increased expression of SPP1 mRNA CTD PMID:22863853 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Nystatin results in increased expression of TIMP1 mRNA CTD PMID:22863853 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO Nystatin inhibits the reaction [Quercetin affects the localization of TNFRSF10A protein] CTD PMID:17876056 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
JBrowse link
G Vim vimentin increases expression ISO Nystatin results in increased expression of VIM mRNA CTD PMID:22863853 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
OSU-03012 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
decreases response to substance
ISO OSU 03012 results in decreased phosphorylation of AKT1 protein
AKT1 protein modified form results in decreased susceptibility to OSU 03012
CTD PMID:15205346 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 multiple interactions
decreases response to substance
ISO OSU 03012 binds to and results in decreased activity of PDPK1 protein
PDPK1 protein modified form results in decreased susceptibility to OSU 03012
CTD PMID:15205346 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
ridaforolimus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO ridaforolimus inhibits the reaction [Radon results in increased expression of ACTA2 protein] CTD PMID:32949624 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO ridaforolimus inhibits the reaction [Radon results in decreased expression of CDH1 protein] CTD PMID:32949624 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO ridaforolimus inhibits the reaction [Radon results in increased expression of CDH2 protein] CTD PMID:32949624 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO ridaforolimus inhibits the reaction [Radon results in increased expression of FN1 protein] CTD PMID:32949624 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases activity
ISO ridaforolimus inhibits the reaction [Radon results in increased expression of MTOR protein modified form]
ridaforolimus results in decreased activity of MTOR protein
CTD PMID:32949624 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO ridaforolimus inhibits the reaction [Radon results in increased expression of SNAI1 protein] CTD PMID:32949624 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Vim vimentin multiple interactions ISO ridaforolimus inhibits the reaction [Radon results in increased expression of VIM protein] CTD PMID:32949624 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
sirolimus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin increases expression EXP Sirolimus results in increased expression of A2M mRNA CTD PMID:21865292 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases expression
ISO
EXP
[Sirolimus co-treated with Cyclosporine] results in decreased expression of ABCA1 protein; [Sirolimus co-treated with Tacrolimus] results in increased expression of ABCA1 protein
Sirolimus results in increased expression of ABCA1 mRNA
CTD PMID:17016853 PMID:21865292 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects metabolic processing
affects transport
ISO ABCB1 protein affects the metabolism of Sirolimus
ABCB1 protein affects the transport of Sirolimus
CTD PMID:15707415 PMID:15760093 PMID:15964407 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression EXP Sirolimus results in decreased expression of ABCC2 mRNA CTD PMID:11589784 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 decreases expression EXP Sirolimus results in decreased expression of ABCC8 mRNA CTD PMID:21865292 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 decreases expression ISO Sirolimus results in decreased expression of ABCD3 protein CTD PMID:36214828 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Abtb3 ankyrin repeat and BTB domain containing 3 multiple interactions ISO Sirolimus inhibits the reaction [TP73 protein results in increased expression of ABTB3 mRNA] CTD PMID:21245298 NCBI chr 7:18,035,151...18,310,718
Ensembl chr 7:18,036,083...18,310,834
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain multiple interactions EXP Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADL mRNA]] CTD PMID:25045214 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions EXP Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of ACADM mRNA]] CTD PMID:25045214 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression EXP Sirolimus results in decreased expression of ACE2 mRNA CTD PMID:21865292 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acer2 alkaline ceramidase 2 multiple interactions ISO Sirolimus inhibits the reaction [TP73 protein results in decreased expression of ACER2 mRNA] CTD PMID:21245298 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [Sirolimus co-treated with IGF1 protein] results in increased expression of ACTA2 protein
Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
CTD PMID:17908691 PMID:35405287 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actb actin, beta increases expression
multiple interactions
ISO Sirolimus results in increased expression of ACTB mRNA
[Sirolimus binds to FKBP1A protein] which results in increased expression of ACTB mRNA
CTD PMID:7503980 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Agt angiotensinogen multiple interactions EXP Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 decreases expression
multiple interactions
EXP
ISO
Sirolimus results in decreased expression of AIFM1 protein
[7-hydroxystaurosporine co-treated with Sirolimus] affects the localization of AIFM1 protein; Boc-D-FMK inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] affects the localization of AIFM1 protein]
CTD PMID:15767555 PMID:16497721 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
affects phosphorylation
increases phosphorylation
ISO
EXP
[Cisplatin inhibits the reaction [[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein]] which results in increased expression of BCL2L11 protein; [Cisplatin inhibits the reaction [[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein]] which results in increased expression of CDKN1B protein; [Sirolimus co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in decreased phosphorylation of AKT1 protein; [Sirolimus co-treated with Arsenic Trioxide] results in decreased phosphorylation of AKT1 protein; Arsenic Trioxide inhibits the reaction [Sirolimus results in increased phosphorylation of AKT1 protein]; Cisplatin inhibits the reaction [[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein]; Cisplatin inhibits the reaction [Sirolimus results in increased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Sirolimus results in increased phosphorylation of AKT1 protein]; Sirolimus affects the reaction [SLC31A1 protein affects the phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [Tretinoin results in increased phosphorylation of AKT1 protein]
[Sirolimus co-treated with Resveratrol] promotes the reaction [TSC2 gene mutant form results in decreased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [[Cadmium Chloride co-treated with TGFB1 protein] results in increased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [[Ethylene Chlorohydrin co-treated with Lipopolysaccharides] results in increased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [AKT1 protein mutant form results in increased phosphorylation of EIF4EBP1 protein]; Sirolimus inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [Pasteurella multocida toxin results in increased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [Resveratrol results in decreased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [TSC1 gene mutant form results in decreased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [TSC2 gene mutant form results in decreased phosphorylation of AKT1 protein]
Sirolimus results in decreased phosphorylation of AKT1 protein
Sirolimus affects the phosphorylation of AKT1 protein
[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein; Sirolimus results in increased phosphorylation of AKT1 protein
resveratrol inhibits the reaction [Sirolimus results in increased phosphorylation of AKT1 protein]; Sirolimus inhibits the reaction [IGF1 protein inhibits the reaction [Isoflurane results in decreased phosphorylation of AKT1 protein]]
CTD PMID:15806154 PMID:18495876 PMID:18622747 PMID:19176369 PMID:21092744 More... NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Akt1s1 AKT1 substrate 1 multiple interactions ISO
EXP
[Sirolimus co-treated with resveratrol] results in decreased phosphorylation of AKT1S1 protein; resveratrol inhibits the reaction [Sirolimus inhibits the reaction [TSC2 gene mutant form results in decreased phosphorylation of AKT1S1 protein]]; Sirolimus inhibits the reaction [TSC2 gene mutant form results in decreased phosphorylation of AKT1S1 protein]
[resveratrol co-treated with Sirolimus] results in decreased phosphorylation of AKT1S1 protein
CTD PMID:24304514 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677
JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions ISO [Sirolimus results in increased activity of AKT2 protein] which results in increased expression of CALD1 protein; [Sirolimus results in increased activity of AKT2 protein] which results in increased expression of MYH11 protein; Sirolimus results in increased phosphorylation of and results in increased activity of AKT2 protein CTD PMID:17908691 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]] CTD PMID:33450223 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Angptl6 angiopoietin-like 6 increases expression EXP Sirolimus results in increased expression of ANGPTL6 mRNA CTD PMID:21865292 NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925
JBrowse link
G Aopep aminopeptidase O multiple interactions ISO Sirolimus inhibits the reaction [TP73 protein results in increased expression of AOPEP mRNA] CTD PMID:21245298 NCBI chr17:1,811,281...2,127,316
Ensembl chr17:1,811,980...2,127,331
JBrowse link
G Apod apolipoprotein D affects localization ISO Sirolimus affects the localization of APOD protein CTD PMID:28182653 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305
JBrowse link
G App amyloid beta precursor protein decreases expression
increases expression
ISO Sirolimus results in decreased expression of APP protein modified form
Sirolimus results in increased expression of APP protein modified form
CTD PMID:20542014 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Aqp2 aquaporin 2 multiple interactions
decreases expression
EXP rosiglitazone inhibits the reaction [Sirolimus results in decreased expression of AQP2 protein] CTD PMID:19656910 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Ar androgen receptor multiple interactions
increases activity
increases expression
ISO [Sirolimus results in decreased activity of [MTOR protein binds to RPTOR protein]] which results in increased activity of AR protein; bicalutamide inhibits the reaction [Sirolimus results in increased activity of AR protein]; RPTOR protein inhibits the reaction [Sirolimus results in increased activity of AR protein]; Sirolimus affects the reaction [Testosterone results in increased expression of AR protein]; Sirolimus promotes the reaction [Dihydrotestosterone affects the expression of AR protein]
Sirolimus results in increased expression of AR protein
CTD PMID:18776922 PMID:21036700 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO Sirolimus inhibits the reaction [IL2 protein results in increased expression of ASNS mRNA] CTD PMID:11355896 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [(+)-JQ1 compound co-treated with Sirolimus] affects the expression of ATF3 mRNA CTD PMID:25307878 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO
EXP
Sirolimus inhibits the reaction [Cadmium Chloride results in increased expression of ATF4]
Sirolimus inhibits the reaction [cadmium acetate results in increased expression of ATF4 protein]
CTD PMID:24057571 PMID:29870746 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO [Sirolimus co-treated with hydroquinone] results in decreased expression of ATF6 protein CTD PMID:37148176 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase increases expression ISO Sirolimus results in increased expression of ATG4A mRNA CTD PMID:21681844 NCBI chr  X:104,665,345...104,765,271
Ensembl chr  X:104,665,345...104,765,268
JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase increases expression
multiple interactions
ISO Sirolimus results in increased expression of ATG4B mRNA
Sirolimus inhibits the reaction [ATG4B protein results in increased expression of HK2 protein]; Sirolimus inhibits the reaction [ATG4B protein results in increased expression of LDHA protein]; Sirolimus inhibits the reaction [ATG4B protein results in increased expression of MTOR protein]; Sirolimus inhibits the reaction [ATG4B protein results in increased expression of SLC2A1 protein]
CTD PMID:21681844 PMID:36336208 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression
ISO
EXP
[Sirolimus co-treated with TNF protein] results in increased expression of ATG5 mRNA; ATG5 protein affects the reaction [Sirolimus inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein]]; Sirolimus inhibits the reaction [Resveratrol inhibits the reaction [Particulate Matter results in increased expression of ATG5 protein]]
[Sirolimus co-treated with cadmium acetate] results in increased expression of ATG5 mRNA; Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of ATG5 protein]; Sirolimus inhibits the reaction [Epirubicin results in decreased expression of ATG5 protein]; Sirolimus inhibits the reaction [OTUD7B protein inhibits the reaction [Doxorubicin results in increased expression of ATG5 protein]]; Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]]
Sirolimus results in increased expression of ATG5 mRNA; Sirolimus results in increased expression of ATG5 protein
CTD PMID:19682553 PMID:29128638 PMID:29505745 PMID:29781141 PMID:29870746 More... NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO [Sirolimus co-treated with TNF protein] results in increased expression of ATG7 mRNA CTD PMID:31676321 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Aurkb aurora kinase B multiple interactions ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of AURKB mRNA CTD PMID:19016759 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO Sirolimus inhibits the reaction [IL2 protein results in increased expression of BAD mRNA] CTD PMID:11355896 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator affects localization
multiple interactions
increases expression
ISO Sirolimus affects the localization of BAX protein
[Curcumin co-treated with Sirolimus] results in increased expression of BAX; Sirolimus affects the reaction [SLC31A1 protein affects the expression of BAX protein]; Sirolimus inhibits the reaction [rebamipide results in decreased expression of BAX protein]; Sirolimus promotes the reaction [hydroquinone results in increased expression of BAX protein]
Sirolimus results in increased expression of BAX protein
[Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased expression of BAX mRNA; [Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased expression of BAX protein; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in increased expression of BAX protein]]; Sirolimus inhibits the reaction [sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of BAX protein]]; Sirolimus inhibits the reaction [triethylene glycol dimethacrylate results in increased expression of BAX protein]
Sirolimus results in increased expression of BAX mRNA; Sirolimus results in increased expression of BAX protein
CTD PMID:11602639 PMID:15782132 PMID:19373661 PMID:19922502 PMID:29054700 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [[Sirolimus co-treated with Cisplatin] results in increased expression of TP73 protein] which results in increased expression of BBC3 protein; Sirolimus promotes the reaction [TP53 protein results in increased expression of BBC3 protein] CTD PMID:19560264 PMID:20686837 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
affects expression
ISO
EXP
[Curcumin co-treated with Sirolimus] results in decreased expression of BCL2; Sirolimus affects the reaction [SLC31A1 protein affects the expression of BCL2 protein]; Sirolimus inhibits the reaction [Colistin results in decreased expression of BCL2 protein]; Sirolimus inhibits the reaction [Doxorubicin results in increased expression of BCL2 protein]; Sirolimus inhibits the reaction [rebamipide results in increased expression of BCL2 protein]; Sirolimus promotes the reaction [Artesunate results in decreased expression of BCL2 protein]; Sirolimus promotes the reaction [Ethanol results in increased expression of BCL2 protein]
Sirolimus results in decreased expression of BCL2 mRNA; Sirolimus results in decreased expression of BCL2 protein
[Sirolimus co-treated with IL2 protein] results in increased expression of BCL2 mRNA; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]]; Sirolimus inhibits the reaction [sophoricoside inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of BCL2 protein]]
Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of BCL2 protein]; Sirolimus inhibits the reaction [lactacystin results in decreased expression of BCL2 protein]; Sirolimus inhibits the reaction [Rotenone results in decreased expression of BCL2 protein]
Sirolimus affects the expression of BCL2 protein
CTD PMID:11355896 PMID:15571967 PMID:18640276 PMID:19373661 PMID:19764996 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
increases expression
ISO [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased expression of BCL2L1 protein; Sirolimus inhibits the reaction [Colistin results in decreased expression of BCL2L1 protein]; Sirolimus inhibits the reaction [Lipopolysaccharides results in increased expression of BCL2L1 protein]; Sirolimus inhibits the reaction [rebamipide results in increased expression of BCL2L1 protein]
Sirolimus results in decreased expression of BCL2L1 protein
[Sirolimus co-treated with IL2 protein] results in increased expression of BCL2L1 mRNA; Sirolimus inhibits the reaction [Lipopolysaccharides results in increased expression of BCL2L1 protein]
Sirolimus results in decreased expression of BCL2L1 mRNA; Sirolimus results in decreased expression of BCL2L1 protein
Sirolimus results in increased expression of BCL2L1 mRNA; Sirolimus results in increased expression of BCL2L1 protein
CTD PMID:11355896 PMID:15767555 PMID:15782132 PMID:18097008 PMID:18789402 More... NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions
increases expression
decreases expression
ISO [Cisplatin inhibits the reaction [[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein]] which results in increased expression of BCL2L11 protein; Sirolimus inhibits the reaction [rebamipide results in decreased expression of BCL2L11 protein]; Sirolimus promotes the reaction [Cisplatin results in increased expression of BCL2L11 mRNA]
Sirolimus results in increased expression of BCL2L11 protein
Sirolimus results in decreased expression of BCL2L11 protein
CTD PMID:18097008 PMID:21092744 PMID:29054700 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Sirolimus inhibits the reaction [BDNF protein results in increased expression of PPP1R1B mRNA]; Sirolimus inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein]; Sirolimus inhibits the reaction [Creatine results in increased expression of BDNF protein]; Sirolimus inhibits the reaction [Ketamine results in increased expression of BDNF protein] CTD PMID:17209049 PMID:33022268 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO
EXP
[Sirolimus co-treated with TNF protein] results in increased expression of BECN1 protein; Sirolimus inhibits the reaction [Ethanol results in increased degradation of BECN1 protein]; Sirolimus inhibits the reaction [Paraquat results in decreased expression of BECN1 protein]; Sirolimus promotes the reaction [2,4,4'-trichlorobiphenyl results in increased expression of BECN1 protein]; Sirolimus promotes the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of BECN1 protein]; Sirolimus promotes the reaction [Caffeine results in increased expression of BECN1 protein]; Sirolimus promotes the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BECN1 protein]
Sirolimus results in increased expression of BECN1 protein
Sirolimus results in increased expression of BECN1 mRNA; Sirolimus results in increased expression of BECN1 protein
[Sirolimus co-treated with cadmium acetate] results in increased expression of BECN1 mRNA; Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of BECN1 protein]; Sirolimus inhibits the reaction [Epirubicin results in decreased expression of BECN1 protein]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in increased expression of BECN1 protein]]; Sirolimus promotes the reaction [2,4,4'-trichlorobiphenyl results in increased expression of BECN1 protein]; Sirolimus promotes the reaction [2,5,2',5'-tetrachlorobiphenyl results in increased expression of BECN1 protein]; Sirolimus promotes the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]
Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of BECN1 protein]; Sirolimus inhibits the reaction [phenanthrene results in decreased expression of BECN1 mRNA]; Sirolimus inhibits the reaction [SIRT4 protein inhibits the reaction [Doxorubicin results in increased expression of BECN1 protein]]; Sirolimus promotes the reaction [Trichloroethylene results in increased expression of BECN1 protein]
CTD PMID:20358864 PMID:21410490 PMID:26648565 PMID:26825372 PMID:27107786 More... NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO Sirolimus inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]
Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of BGLAP mRNA]]
CTD PMID:23111315 PMID:33450223 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
decreases expression
increases expression
ISO [7-hydroxystaurosporine co-treated with Sirolimus] results in increased cleavage of BID protein
[Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased expression of BID mRNA; [Sirolimus results in decreased activity of RPS6KB1 protein] which results in increased expression of BID protein
Sirolimus results in decreased expression of BID protein
Sirolimus results in increased expression of BID mRNA; Sirolimus results in increased expression of BID protein
CTD PMID:15767555 PMID:18097008 PMID:19922502 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions
affects localization
increases expression
ISO
EXP
Sirolimus inhibits the reaction [Doxorubicin results in increased expression of BIRC2 protein]
Sirolimus affects the localization of BIRC2 protein
Sirolimus results in increased expression of BIRC2 protein
CTD PMID:15571967 PMID:21357504 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of BIRC5 mRNA; Sirolimus inhibits the reaction [N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide results in increased expression of and affects the localization of BIRC5 protein]; Sirolimus promotes the reaction [Tamoxifen results in decreased expression of BIRC5 protein]
Sirolimus results in decreased expression of BIRC5 protein
CTD PMID:19016759 PMID:19931998 PMID:21601561 PMID:24444656 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO Sirolimus inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA] CTD PMID:23111315 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions ISO Sirolimus inhibits the reaction [IL2 protein results in increased expression of BNIP3 mRNA] CTD PMID:11355896 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Btc betacellulin multiple interactions EXP Sirolimus inhibits the reaction [BTC protein affects the localization of CDKN1A protein]; Sirolimus inhibits the reaction [BTC protein affects the localization of CDKN1B protein]; Sirolimus inhibits the reaction [BTC protein results in increased expression of CCND1 protein] CTD PMID:19105244 NCBI chr14:16,708,447...16,746,961
Ensembl chr14:16,707,982...16,747,049
JBrowse link
G Btk Bruton tyrosine kinase multiple interactions ISO Sirolimus inhibits the reaction [IL2 protein results in increased expression of BTK mRNA] CTD PMID:11355896 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of BUB1 mRNA CTD PMID:19016759 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of BUB1B mRNA CTD PMID:19016759 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G C1qa complement C1q A chain decreases expression EXP Sirolimus results in decreased expression of C1QA mRNA CTD PMID:21865292 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G C1qc complement C1q C chain decreases expression EXP Sirolimus results in decreased expression of C1QC mRNA CTD PMID:21865292 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G C3 complement C3 decreases expression EXP Sirolimus results in decreased expression of C3 mRNA CTD PMID:21865292 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
JBrowse link
G Cald1 caldesmon 1 multiple interactions
increases expression
ISO [Sirolimus co-treated with IGF1 protein] results in increased expression of CALD1 protein; [Sirolimus results in increased activity of AKT2 protein] which results in increased expression of CALD1 protein
Sirolimus results in increased expression of CALD1 protein
CTD PMID:17908691 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Sirolimus inhibits the reaction [Cadmium Chloride results in increased phosphorylation of CAMK2A protein] CTD PMID:21933187 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Capn1 calpain 1 decreases activity EXP Sirolimus results in decreased activity of CAPN1 protein CTD PMID:21357504 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Casp1 caspase 1 multiple interactions ISO
EXP
Sirolimus inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]
Sirolimus inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]
Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased cleavage of CASP1 protein]; Sirolimus inhibits the reaction [Trichloroethylene results in increased expression of CASP1 mRNA]
CTD PMID:30205151 PMID:31586597 PMID:35405287 PMID:36849104 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp12 caspase 12 decreases cleavage
multiple interactions
ISO
EXP
Sirolimus results in decreased cleavage of CASP12 protein
Sirolimus inhibits the reaction [cadmium acetate results in increased expression of CASP12 protein]
CTD PMID:20511674 PMID:29870746 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp2 caspase 2 multiple interactions ISO [Boc-D-FMK co-treated with Sirolimus] results in increased cleavage of CASP2 protein; Boc-D-FMK inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased cleavage of CASP2 protein] CTD PMID:15767555 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
increases expression
decreases activity
ISO
EXP
[7-hydroxystaurosporine co-treated with Sirolimus] results in increased cleavage of CASP3 protein; [Curcumin co-treated with Sirolimus] results in increased activity of CASP3 protein; [S 1 (combination) co-treated with Sirolimus] results in increased expression of CASP3 protein; [Sirolimus co-treated with Paclitaxel] results in increased cleavage of CASP3 protein; Boc-D-FMK inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased cleavage of CASP3 protein]; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CASP3 mRNA]; MCL1 protein inhibits the reaction [Sirolimus inhibits the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]]; pyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [[[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; Sirolimus inhibits the reaction [Colistin results in increased activity of CASP3 protein]; Sirolimus inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [Rotenone results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [TNF protein results in increased cleavage of CASP3 protein]; Sirolimus promotes the reaction [Artesunate results in increased cleavage of CASP3 protein]; Sirolimus promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Sirolimus promotes the reaction [Doxorubicin results in increased activity of CASP3 protein]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CASP3 mRNA]
Sirolimus results in increased activity of CASP3 protein
Sirolimus results in increased cleavage of CASP3 protein
Sirolimus results in decreased activity of CASP3 protein
Sirolimus results in increased expression of CASP3 mRNA; Sirolimus results in increased expression of CASP3 protein
[Sirolimus co-treated with Resveratrol] results in increased cleavage of CASP3 protein; Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [decamethrin results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [Staurosporine results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; Sirolimus promotes the reaction [decamethrin results in increased cleavage of CASP3 protein]; Sirolimus results in decreased cleavage of and results in decreased activity of CASP3 protein
Sirolimus inhibits the reaction [[Rotenone co-treated with Particulate Matter] results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Sirolimus inhibits the reaction [gelsenicine results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [TGFB1 protein inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]]; Sirolimus inhibits the reaction [triethylene glycol dimethacrylate results in increased cleavage of CASP3 protein]; Sirolimus promotes the reaction [Alpha-Amanitin results in increased cleavage of CASP3 protein]; Sirolimus promotes the reaction [Cadmium results in increased cleavage of CASP3 protein]
Sirolimus results in increased expression of CASP3 protein modified form
CTD PMID:14502240 PMID:15571967 PMID:15753396 PMID:15767555 PMID:15782132 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
decreases activity
ISO
EXP
[Curcumin co-treated with Sirolimus] results in increased activity of CASP7 protein; [Sirolimus co-treated with Paclitaxel] results in increased cleavage of CASP7 protein
Sirolimus results in decreased activity of CASP7 protein
CTD PMID:15753396 PMID:19373661 PMID:20031680 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
ISO [7-hydroxystaurosporine co-treated with Sirolimus] results in increased cleavage of CASP8 protein; [tanespimycin co-treated with Sirolimus] results in increased cleavage of CASP8 protein; pyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased cleavage of CASP8 protein]; Sirolimus promotes the reaction [Cisplatin results in increased cleavage of CASP8 protein]
Sirolimus results in increased cleavage of CASP8 protein
Sirolimus inhibits the reaction [TGFB1 protein inhibits the reaction [Cadmium Chloride results in increased expression of CASP8 protein]]
CTD PMID:15767555 PMID:17121904 PMID:18058806 PMID:25307878 PMID:28342888 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
decreases activity
ISO
EXP
[7-hydroxystaurosporine co-treated with Sirolimus] results in increased cleavage of CASP9 protein; [Curcumin co-treated with Sirolimus] results in increased activity of CASP9 protein; [Sirolimus co-treated with Cisplatin] results in increased activity of CASP9 protein; [Sirolimus co-treated with Paclitaxel] results in increased cleavage of CASP9 protein; [tanespimycin co-treated with Sirolimus] results in increased cleavage of CASP9 protein; Sirolimus inhibits the reaction [Colistin results in increased activity of CASP9 protein]; Sirolimus promotes the reaction [Cisplatin results in increased cleavage of CASP9 protein]
Sirolimus results in decreased activity of CASP9 protein
[Swainsonine co-treated with Sirolimus] results in increased cleavage of CASP9 protein; Sirolimus inhibits the reaction [Staurosporine results in increased cleavage of CASP9 protein]
Sirolimus inhibits the reaction [TGFB1 protein inhibits the reaction [Cadmium Chloride results in increased expression of CASP9 protein]]
CTD PMID:15753396 PMID:15767555 PMID:16497721 PMID:17121904 PMID:18058806 More... NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression ISO Sirolimus results in increased expression of CAT protein CTD PMID:30905858 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav3 caveolin 3 multiple interactions ISO Sirolimus inhibits the reaction [TP73 protein results in increased expression of CAV3 mRNA] CTD PMID:21245298 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP Sirolimus results in increased expression of CCN2 mRNA CTD PMID:21865292 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of CCNA2 mRNA
Sirolimus results in decreased expression of CCNA2; Sirolimus results in decreased expression of CCNA2 protein
CTD PMID:7503980 PMID:8419408 PMID:19016759 PMID:19505958 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of CCNB2 mRNA CTD PMID:19016759 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases degradation
increases expression
decreases expression
ISO
EXP
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Sirolimus results in increased expression of CCND1 protein]; [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine co-treated with Sirolimus] results in decreased expression of CCND1; [3-(3-chloro-4-hydroxyphenylamino)-4-(4-nitrophenyl)-1H-pyrrole-2,5-dione results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased expression of CCND1 protein; [Lithium Chloride results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; [SB 216763 results in decreased activity of GSK3B protein] inhibits the reaction [Sirolimus results in decreased expression of CCND1 protein]; [Sirolimus co-treated with Letrozole] results in decreased expression of CCND1 protein; [Sirolimus co-treated with tanespimycin] results in decreased expression of CCND1 protein; [Sirolimus results in increased activity of GSK3B protein] which results in increased phosphorylation of and results in increased degradation of CCND1 protein; Curcumin inhibits the reaction [Sirolimus results in increased expression of CCND1 protein]
Sirolimus results in increased degradation of CCND1 protein
Sirolimus inhibits the reaction [BTC protein results in increased expression of CCND1 protein]; Sirolimus inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]
CTD PMID:7532117 PMID:15753396 PMID:15767555 PMID:17121904 PMID:19105244 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 multiple interactions
decreases expression
ISO
EXP
[Sirolimus co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [IL2 protein results in increased expression of CCND2 protein]; Sirolimus inhibits the reaction [IL2 protein results in increased expression of CCND2 mRNA]
Sirolimus inhibits the reaction [FSHB protein results in increased expression of CCND2 mRNA]
Sirolimus results in decreased expression of CCND2 protein
CTD PMID:15070696 PMID:15778701 PMID:17510244 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 multiple interactions
decreases stability
decreases expression
ISO [Sirolimus co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [IL2 protein results in increased expression of CCND3 protein]; Sirolimus inhibits the reaction [IL2 protein results in increased expression of CCND3 mRNA]
Sirolimus results in decreased stability of CCND3 mRNA
Sirolimus inhibits the reaction [KITL protein results in increased expression of CCND3 protein]
Sirolimus results in decreased expression of CCND3 mRNA; Sirolimus results in decreased expression of CCND3 protein
CTD PMID:10849422 PMID:12393642 PMID:15070696 PMID:15778701 PMID:15882288 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 multiple interactions
increases expression
ISO Curcumin inhibits the reaction [Sirolimus results in increased expression of CCNE1 protein] CTD PMID:36640941 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO [Fulvestrant co-treated with Sirolimus] results in decreased expression of CCNE2 mRNA; Sirolimus inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA] CTD PMID:19016759 PMID:27542212 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression
ISO [cotylenin A co-treated with Sirolimus] results in increased expression of CCNG2 mRNA; Sirolimus inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]; Sirolimus inhibits the reaction [TP73 protein results in increased expression of CCNG2 mRNA]
Sirolimus results in increased expression of CCNG2 mRNA
CTD PMID:18754885 PMID:21245298 PMID:24356939 PMID:27542212 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Ccni cyclin I multiple interactions ISO Sirolimus inhibits the reaction [IL2 protein results in decreased expression of CCNI mRNA] CTD PMID:11355896 NCBI chr14:14,879,698...14,902,510
Ensembl chr14:14,879,717...14,902,510
JBrowse link
G Cd36 CD36 molecule affects expression
multiple interactions
ISO Sirolimus affects the expression of CD36 protein
Sirolimus inhibits the reaction [Oxygen deficiency results in increased expression of CD36 mRNA]
CTD PMID:17016853 PMID:19640849 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO CD38 gene mutant form promotes the reaction [Sirolimus results in increased expression of MAP1LC3B protein]; CD38 mutant form inhibits the reaction [Sirolimus results in decreased expression of SQSTM1 protein] CTD PMID:24238063 PMID:24445604 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cd68 Cd68 molecule decreases expression ISO
EXP
Sirolimus results in decreased expression of CD68 mRNA CTD PMID:17016853 PMID:21865292 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd80 Cd80 molecule decreases expression ISO Sirolimus results in decreased expression of CD80 protein CTD PMID:12531798 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd84 CD84 molecule increases expression ISO Sirolimus results in increased expression of CD84 mRNA CTD PMID:24356939 NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
JBrowse link
G Cd86 CD86 molecule decreases expression ISO Sirolimus results in decreased expression of CD86 protein CTD PMID:12531798 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of CDC20 mRNA CTD PMID:19016759 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions
ISO
EXP
Sirolimus results in increased expression of CDH1 protein
Sirolimus inhibits the reaction [sodium arsenite results in decreased expression of CDH1 protein]
NFE2L2 protein promotes the reaction [Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]]; Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 mRNA]; Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]; Sirolimus promotes the reaction [Dibutyl Phthalate results in decreased expression of CDH1 mRNA]; Sirolimus promotes the reaction [Dibutyl Phthalate results in decreased expression of CDH1 protein]
CTD PMID:28624451 PMID:28888487 PMID:30053495 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP Sirolimus promotes the reaction [Dibutyl Phthalate results in increased expression of CDH2 mRNA]; Sirolimus promotes the reaction [Dibutyl Phthalate results in increased expression of CDH2 protein] CTD PMID:30053495 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression
decreases activity
ISO
EXP
[7-hydroxystaurosporine co-treated with Sirolimus] results in decreased expression of CDK1 mRNA; [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased expression of CDK1 protein; [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased phosphorylation of CDK1 protein; [fulvestrant co-treated with Sirolimus] results in decreased expression of CDK1 mRNA
Sirolimus results in decreased expression of CDK1
Sirolimus inhibits the reaction [IL2 protein results in increased expression of CDK1 mRNA]
Sirolimus results in decreased activity of CDK1 protein
Sirolimus results in decreased expression of CDK1 mRNA; Sirolimus results in decreased expression of CDK1 protein
CTD PMID:7503980 PMID:7532117 PMID:8419408 PMID:11355896 PMID:15767555 More... NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
ISO
EXP
[Sirolimus co-treated with TGFB1 protein] affects the localization of CDK2 protein; [Sirolimus co-treated with TGFB1 protein] promotes the reaction [CDKN1A protein binds to CDK2 protein]; [TGFB1 protein co-treated with Sirolimus] inhibits the reaction [[E2F4 protein binds to RBL1 protein] which binds to CDK2 protein]; [TGFB1 protein co-treated with Sirolimus] inhibits the reaction [[E2F4 protein binds to RBL2 protein] which binds to CDK2 protein]; [TGFB1 protein co-treated with Sirolimus] promotes the reaction [CDK2 protein binds to CDKN1A protein]; [TGFB1 protein co-treated with Sirolimus] promotes the reaction [CDK2 protein binds to CDKN1B protein]; [TGFB1 protein co-treated with Sirolimus] results in decreased activity of CDK2 protein; [TGFB1 protein co-treated with Sirolimus] results in decreased phosphorylation of CDK2 protein
Sirolimus results in decreased activity of CDK2 protein
[Sirolimus co-treated with TGFB1 protein] affects the localization of CDK2 protein; [Sirolimus co-treated with TGFB1 protein] promotes the reaction [CDKN1B protein binds to CDK2 protein]; [Sirolimus co-treated with TGFB1 protein] results in decreased activity of CDK2 protein; [TGFB1 protein co-treated with Sirolimus] promotes the reaction [CDK2 protein binds to CDKN1B protein]
CTD PMID:7532117 PMID:12393642 PMID:12417722 PMID:14979923 PMID:21528311 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Sirolimus results in decreased expression of CDK4 protein CTD PMID:22761470 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
decreases expression
ISO
EXP
[(+)-JQ1 compound co-treated with Sirolimus] results in increased expression of CDKN1A mRNA; [(+)-JQ1 compound co-treated with Sirolimus] results in increased expression of CDKN1A protein; [S 1 (combination) co-treated with Sirolimus] results in increased expression of CDKN1A protein; [Sirolimus co-treated with TGFB1 protein] promotes the reaction [CDKN1A protein binds to CDK2 protein]; [Sirolimus co-treated with TGFB1 protein] results in increased expression of CDKN1A protein; [TGFB1 protein co-treated with Sirolimus] promotes the reaction [CDK2 protein binds to CDKN1A protein]; [TGFB1 protein co-treated with Sirolimus] results in increased expression of CDKN1A protein; Fluorouracil promotes the reaction [Sirolimus results in increased expression of CDKN1A mRNA]; Sirolimus inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]; Sirolimus promotes the reaction [(+)-JQ1 compound results in increased expression of CDKN1A mRNA]; Sirolimus promotes the reaction [(+)-JQ1 compound results in increased expression of CDKN1A protein]; Sirolimus promotes the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]]; Sirolimus promotes the reaction [Fluorouracil results in increased expression of CDKN1A mRNA]
Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; Sirolimus inhibits the reaction [BTC protein affects the localization of CDKN1A protein]; Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; Sirolimus inhibits the reaction [IGF1 protein affects the localization of CDKN1A protein]; SIRT1 protein promotes the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]
Sirolimus results in increased expression of CDKN1A mRNA; Sirolimus results in increased expression of CDKN1A protein
Sirolimus results in decreased expression of CDKN1A protein
Sirolimus inhibits the reaction [arsenite results in increased expression of CDKN1A protein]
CTD PMID:12417722 PMID:14979923 PMID:17700525 PMID:19105244 PMID:19764996 More... NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
decreases degradation
increases expression
decreases expression
ISO
EXP
[Cisplatin inhibits the reaction [[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein]] which results in increased expression of CDKN1B protein; [Decitabine co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Sirolimus] results in increased expression of CDKN1B mRNA; [Sirolimus co-treated with TGFB1 protein] affects the localization of CDKN1B protein; [TGFB1 protein co-treated with Sirolimus] promotes the reaction [CDK2 protein binds to CDKN1B protein]; Sirolimus promotes the reaction [Cisplatin results in increased expression of CDKN1B mRNA]
Sirolimus results in decreased degradation of CDKN1B protein
[Sirolimus co-treated with TGFB1 protein] affects the localization of CDKN1B protein; [Sirolimus co-treated with TGFB1 protein] promotes the reaction [CDKN1B protein binds to CDK2 protein]; [TGFB1 protein co-treated with Sirolimus] promotes the reaction [CDK2 protein binds to CDKN1B protein]
Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]; Sirolimus inhibits the reaction [BTC protein affects the localization of CDKN1B protein]; Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]; Sirolimus inhibits the reaction [IGF1 protein affects the localization of CDKN1B protein]; SIRT1 protein promotes the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]
Sirolimus results in increased expression of CDKN1B protein
Sirolimus results in decreased expression of CDKN1B protein
CTD PMID:12417722 PMID:12565877 PMID:14979923 PMID:15070696 PMID:16455087 More... NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdx2 caudal type homeo box 2 increases expression ISO Sirolimus results in increased expression of CDX2 mRNA CTD PMID:21681844 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO Sirolimus results in decreased expression of CEBPA mRNA CTD PMID:15358118 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO Sirolimus inhibits the reaction [Endrin results in increased expression of CEBPD mRNA] CTD PMID:34801515 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cenpx centromere protein X increases expression ISO Sirolimus results in increased expression of CENPX mRNA CTD PMID:11355896 NCBI chr10:105,991,469...105,994,310 JBrowse link
G Cfd complement factor D decreases expression ISO Sirolimus results in decreased expression of CFD mRNA CTD PMID:15358118 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit multiple interactions ISO Sirolimus inhibits the reaction [TP73 protein results in increased expression of CHRNB3 mRNA] CTD PMID:21245298 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO Sirolimus inhibits the reaction [[Ethylene Chlorohydrin co-treated with Lipopolysaccharides] results in increased expression of CIDEC mRNA] CTD PMID:31499194 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression ISO Sirolimus results in decreased expression of CKS1B mRNA CTD PMID:11355896 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636
JBrowse link
G Cldn7 claudin 7 increases expression EXP Sirolimus results in increased expression of CLDN7 mRNA CTD PMID:21865292 NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 decreases expression EXP Sirolimus results in decreased expression of CLEC4A mRNA CTD PMID:21865292 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817
JBrowse link
G Cluh clustered mitochondria homolog increases expression ISO Sirolimus results in increased expression of CLUH protein CTD PMID:36214828 NCBI chr10:59,509,580...59,531,345
Ensembl chr10:59,509,726...59,531,345
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions
EXP
ISO
Sirolimus results in decreased expression of COL1A1 mRNA
Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]
CTD PMID:21865292 PMID:35405287 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO
EXP
Sirolimus inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA]
Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]
CTD PMID:10535884 PMID:11343241 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO Sirolimus results in decreased expression of COL2A1 protein CTD PMID:34536393 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Cp ceruloplasmin increases expression EXP Sirolimus results in increased expression of CP mRNA CTD PMID:21865292 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions EXP Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT1B mRNA]] CTD PMID:25045214 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions EXP Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]; TNF protein inhibits the reaction [Sirolimus inhibits the reaction [Isoproterenol results in decreased expression of CPT2 mRNA]] CTD PMID:25045214 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [Sirolimus results in decreased activity of MTOR protein] inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of CREB1 protein]] CTD PMID:22363816 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebrf CREB3 regulatory factor multiple interactions ISO [(+)-JQ1 compound co-treated with Sirolimus] affects the expression of CREBRF mRNA CTD PMID:25307878 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 decreases activity ISO Sirolimus results in decreased activity of CRTC2 protein CTD PMID:23440206 NCBI chr 2:175,709,603...175,719,768
Ensembl chr 2:175,709,644...175,719,763
JBrowse link
G Cs citrate synthase multiple interactions ISO Sirolimus affects the reaction [triethylene glycol dimethacrylate affects the activity of CS protein] CTD PMID:33684387 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
JBrowse link
G Cse1l chromosome segregation 1 like decreases expression ISO Sirolimus results in decreased expression of CSE1L mRNA CTD PMID:11355896 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO Sirolimus inhibits the reaction [CSF1 protein results in increased phosphorylation of EIF4EBP1 protein]; Sirolimus inhibits the reaction [CSF1 protein results in increased phosphorylation of RPS6 protein] CTD PMID:14502240 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]] CTD PMID:1376361 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP Sirolimus promotes the reaction [Dibutyl Phthalate results in increased expression of CTNNB1 mRNA] CTD PMID:30053495 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsk cathepsin K multiple interactions
decreases expression
ISO PDCD4 mutant form inhibits the reaction [Sirolimus inhibits the reaction [Pasteurella multocida toxin results in increased expression of CTSK mRNA]]; Sirolimus inhibits the reaction [Pasteurella multocida toxin results in increased activity of CTSK protein]; Sirolimus inhibits the reaction [Pasteurella multocida toxin results in increased expression of CTSK mRNA]
Sirolimus results in decreased expression of CTSK mRNA
CTD PMID:26369790 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP Sirolimus results in decreased expression of CXCL10 mRNA CTD PMID:21865292 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 decreases expression EXP Sirolimus results in decreased expression of CXCL13 mRNA CTD PMID:21865292 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP Sirolimus inhibits the reaction [Cadmium Chloride results in increased expression of CYBA protein] CTD PMID:21195169 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions EXP Sirolimus inhibits the reaction [Cadmium Chloride results in increased expression of CYBB protein] CTD PMID:21195169 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Sirolimus results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO [Cyclosporine co-treated with Sirolimus] results in decreased activity of CYP27A1 protein
Sirolimus results in decreased activity of CYP27A1 protein
CTD PMID:17516993 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Sirolimus results in increased expression of CYP2B6 mRNA CTD PMID:25929522 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Sirolimus affects the reaction [FXN protein affects the reaction [CYP2E1 protein affects the susceptibility to Ethanol]] CTD PMID:33017621 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing ISO CYP3A4 protein affects the metabolism of Sirolimus; CYP3A4 protein polymorphism affects the metabolism of Sirolimus CTD PMID:15707415 PMID:15964407 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO
EXP
Sirolimus inhibits the reaction [arsenite results in increased expression of DDIT3 protein]; Sirolimus inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 protein]
Sirolimus inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; Sirolimus inhibits the reaction [TSC2 gene mutant form results in increased expression of DDIT3 protein]
[(+)-JQ1 compound co-treated with Sirolimus] affects the expression of DDIT3 mRNA; [Sirolimus results in decreased activity of MTOR protein] which results in decreased expression of DDIT3 protein; Sirolimus inhibits the reaction [arsenite results in increased expression of DDIT3 mRNA]; Sirolimus inhibits the reaction [arsenite results in increased expression of DDIT3 protein]; Sirolimus inhibits the reaction [honokiol results in increased expression of DDIT3 protein]
CTD PMID:11145585 PMID:19420259 PMID:21321189 PMID:22215663 PMID:25307878 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4l DNA-damage-inducible transcript 4-like increases expression
decreases expression
EXP Sirolimus results in increased expression of DDIT4L mRNA
Sirolimus results in decreased expression of DDIT4L mRNA
CTD PMID:21865292 NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein multiple interactions ISO Sirolimus inhibits the reaction [TP73 protein results in increased expression of DEPTOR mRNA] CTD PMID:21245298 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [7-hydroxystaurosporine co-treated with Sirolimus] affects the localization of DIABLO protein; Boc-D-FMK inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] affects the localization of DIABLO protein] CTD PMID:15767555 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions ISO Sirolimus inhibits the reaction [Ketamine results in increased expression of DLG4 protein] CTD PMID:33022268 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 decreases expression EXP Sirolimus results in decreased expression of DNAJC6 mRNA CTD PMID:21865292 NCBI chr 5:116,120,069...116,283,448
Ensembl chr 5:116,119,676...116,283,448
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of and results in increased cleavage of DNM1L protein] CTD PMID:35405287 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions ISO [fulvestrant co-treated with Sirolimus] results in decreased expression of DNMT1 mRNA CTD PMID:19016759 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression