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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:carbamate fungicide
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Accession:CHEBI:87061 term browser browse the term
Definition:Compounds that contain a carbamate ester moiety as a key feature of their structure and which have been used as fungicides.
Synonyms:related_synonym: carbamate fungicides



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3-iodoprop-2-yn-1-yl butylcarbamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO 3-iodo-2-propynylbutylcarbamate inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 3-iodo-2-propynylbutylcarbamate binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 3-iodo-2-propynylbutylcarbamate binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO 3-iodo-2-propynylbutylcarbamate binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO 3-iodo-2-propynylbutylcarbamate binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tp53 tumor protein p53 affects activity ISO 3-iodo-2-propynylbutylcarbamate affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
albendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy7 adenylate cyclase 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ADCY7 mRNA CTD PMID:16861626 NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of ARL4C mRNA CTD PMID:16861626 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of BAG3 mRNA CTD PMID:16861626 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Albendazole results in increased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCL3 protein CTD PMID:16861626 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CCR7 mRNA CTD PMID:16861626 NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCT3 mRNA CTD PMID:16861626 NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO [Albendazole co-treated with CYP3A4 protein] results in increased expression of CD86 protein CTD PMID:22785256 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CTSL mRNA CTD PMID:16861626 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases activity
increases expression
ISO Albendazole results in increased activity of CYP1A1 promoter; Albendazole results in increased activity of CYP1A1 protein
Albendazole results in decreased activity of CYP1A1 protein
Albendazole results in increased expression of CYP1A1 mRNA
CTD PMID:12451431 PMID:16714371 PMID:18502397 PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
affects metabolic processing
ISO Albendazole results in increased expression of CYP1A2 mRNA
CYP1A2 protein affects the metabolism of Albendazole
CTD PMID:12451431 PMID:12920490 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Albendazole results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP
ISO
[SOD2 co-treated with CYP3A4] affects the susceptibility to Albendazole
[Albendazole co-treated with CYP3A4 protein] results in increased expression of CD86 protein; [Albendazole co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein
CTD PMID:19501153 PMID:22785256 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DNAJB1 mRNA CTD PMID:16861626 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DPYSL2 mRNA CTD PMID:16861626 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of GEM mRNA CTD PMID:16861626 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gpr183 G protein-coupled receptor 183 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of GPR183 mRNA CTD PMID:16861626 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Albendazole results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AA1 mRNA CTD PMID:16861626 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AB1 mRNA CTD PMID:16861626 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA4 mRNA CTD PMID:16861626 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA8 mRNA CTD PMID:16861626 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPD1 mRNA CTD PMID:16861626 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPE1 mRNA CTD PMID:16861626 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPH1 mRNA CTD PMID:16861626 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Albendazole co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein CTD PMID:22785256 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL10 protein CTD PMID:16861626 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein CTD PMID:16861626 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1R1 mRNA CTD PMID:16861626 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO Albendazole results in increased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of MAP3K8 mRNA CTD PMID:16861626 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Albendazole results in decreased expression of MAPT mRNA; Albendazole results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Albendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPID mRNA CTD PMID:16861626 NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221
JBrowse link
G Ppif peptidylprolyl isomerase F multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPIF mRNA CTD PMID:16861626 NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of PTGES3 mRNA CTD PMID:16861626 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO Albendazole affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of SKAP2 mRNA CTD PMID:16861626 NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:80,950,580...81,100,891
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [SOD2 co-treated with CYP3A4] affects the susceptibility to Albendazole CTD PMID:19501153 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of SPHK1 mRNA CTD PMID:16861626 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
JBrowse link
G St13 ST13, Hsp70 interacting protein multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ST13 mRNA CTD PMID:16861626 NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945
JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of TCP1 mRNA CTD PMID:16861626 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TGIF1 mRNA CTD PMID:16861626 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
ISO U 0126 inhibits the reaction [Albendazole results in increased secretion of TNF protein] CTD PMID:20848085 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 affects activity ISO Albendazole affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TSC22D1 mRNA CTD PMID:16861626 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Albendazole results in increased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
albendazole S-oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects transport ISO ABCG2 protein affects the transport of albendazole sulfoxide CTD PMID:15703302 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO albendazole sulfoxide inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Tp53 tumor protein p53 affects activity ISO albendazole sulfoxide affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
benomyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam33 ADAM metallopeptidase domain 33 multiple interactions
increases expression
ISO ORMDL3 protein affects the reaction [Benomyl results in increased expression of ADAM33 protein] CTD PMID:27784618 NCBI chr 3:118,262,395...118,283,456
Ensembl chr 3:118,271,029...118,283,461
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP Benomyl results in decreased expression of AKT1 mRNA CTD PMID:33930522 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity ISO
EXP
Benomyl metabolite results in decreased activity of ALDH2 protein; Benomyl results in decreased activity of ALDH2 protein CTD PMID:9585485 PMID:10513990 PMID:11142365 PMID:15331769 PMID:17010440 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases activity EXP Benomyl results in decreased activity of ALDH5A1 protein CTD PMID:17010440 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 decreases expression EXP Benomyl results in decreased expression of AMPD3 mRNA CTD PMID:15885261 NCBI chr 1:164,884,823...164,929,899
Ensembl chr 1:164,885,320...164,929,887
JBrowse link
G Ar androgen receptor multiple interactions ISO Benomyl inhibits the reaction [Dihydrotestosterone affects the localization of and results in increased phosphorylation of AR protein] CTD PMID:25324206 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Benomyl inhibits the reaction [BCL2 protein binds to BAX protein] CTD PMID:16903866 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases phosphorylation
ISO Benomyl inhibits the reaction [BCL2 protein binds to BAX protein]
Benomyl results in increased phosphorylation of BCL2 protein
CTD PMID:16903866 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO Benomyl results in increased expression of BUB1B protein CTD PMID:16903866 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Benomyl results in increased expression of CA2 mRNA CTD PMID:15885261 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression
multiple interactions
ISO Benomyl results in increased expression of CCL17 mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of CCL17 mRNA]
CTD PMID:27784618 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccnb1 cyclin B1 increases response to substance ISO CCNB1 protein results in increased susceptibility to Benomyl CTD PMID:11960377 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 increases response to substance ISO CCNB2 protein results in increased susceptibility to Benomyl CTD PMID:11960377 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Cd38 CD38 molecule decreases expression EXP Benomyl results in decreased expression of CD38 mRNA CTD PMID:15885261 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO Benomyl results in decreased expression of CYP17A1 mRNA
Benomyl results in decreased expression of and results in decreased activity of CYP17A1 protein
CTD PMID:25324206 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
ISO Benomyl results in increased activity of CYP19A1 protein
Benomyl results in increased expression of CYP19A1 mRNA
CTD PMID:14691014 PMID:25543211 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of DDIT3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of DDIT3 protein] CTD PMID:27784618 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
ISO Benomyl results in increased expression of EIF2AK3 protein
Acetylcysteine inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]
CTD PMID:27784618 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of ERN1 protein] CTD PMID:27784618 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
ISO Benomyl binds to and results in increased activity of ESR1 protein; Benomyl inhibits the reaction [Estradiol binds to ESR1 protein]
Benomyl binds to ESR1 protein
CTD PMID:14579009 PMID:16626760 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 increases expression EXP Benomyl results in increased expression of FGFR4 mRNA CTD PMID:15885261 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 increases expression EXP Benomyl results in increased expression of GIPC1 mRNA CTD PMID:15885261 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
JBrowse link
G Glyat glycine-N-acyltransferase increases expression EXP Benomyl results in increased expression of GLYAT mRNA CTD PMID:15885261 NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942
JBrowse link
G Hdac1 histone deacetylase 1 decreases activity ISO Benomyl results in decreased activity of HDAC1 protein CTD PMID:25543211 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO Benomyl results in increased expression of HSPA5 protein
Acetylcysteine inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]
CTD PMID:27784618 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Benomyl results in increased expression of HSPB1 mRNA CTD PMID:15885261 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Benomyl inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO Benomyl results in decreased expression of ITGA5 mRNA CTD PMID:25530041 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Benomyl results in decreased expression of ITGB1 mRNA CTD PMID:25530041 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 multiple interactions ISO Benomyl inhibits the reaction [Dihydrotestosterone results in increased secretion of KLK3 protein] CTD PMID:25324206 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression EXP Benomyl results in increased expression of MAPK8 mRNA CTD PMID:33930522 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mir21 microRNA 21 decreases expression EXP Benomyl results in decreased expression of MIR21 mRNA CTD PMID:33930522 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions
increases expression
ISO Benomyl results in decreased expression of MMP2 mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of MMP2 protein]
CTD PMID:25530041 PMID:27784618 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression EXP
ISO
Benomyl results in decreased expression of MMP9 protein
Benomyl results in decreased expression of MMP9 mRNA
CTD PMID:10026946 PMID:25530041 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mmrn1 multimerin 1 increases expression EXP Benomyl results in increased expression of MMRN1 mRNA CTD PMID:15885261 NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474
JBrowse link
G Msmb microseminoprotein, beta increases expression EXP Benomyl results in increased expression of MSMB mRNA CTD PMID:15885261 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123
JBrowse link
G Mt2A metallothionein 2A increases expression EXP Benomyl results in increased expression of MT2A mRNA CTD PMID:15885261 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Benomyl inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Benomyl inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Or10al27 olfactory receptor family 10 subfamily AL member 27 increases expression EXP Benomyl results in increased expression of OR10AL27 mRNA CTD PMID:15885261 NCBI chr20:789,272...790,237
Ensembl chr20:761,025...765,744
Ensembl chr20:761,025...765,744
JBrowse link
G Or13p4 olfactory receptor family 13 subfamily P member 4 increases expression EXP Benomyl results in increased expression of OR13P4 mRNA CTD PMID:15885261 NCBI chr 5:132,216,822...132,217,769
Ensembl chr 5:132,215,327...132,221,481
JBrowse link
G Or9s23b olfactory receptor family 9 subfamily S member 23B increases expression EXP Benomyl results in increased expression of OR9S23B mRNA CTD PMID:15885261 NCBI chr 9:93,117,328...93,118,299
Ensembl chr 9:93,115,232...93,123,441
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ORMDL3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of ORMDL3 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of ADAM33 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of CCL17 mRNA]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of CXCL8 mRNA]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of MMP2 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of TSLP mRNA] CTD PMID:27784618 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620
JBrowse link
G Park7 Parkinsonism associated deglycase decreases activity ISO Benomyl results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Benomyl results in increased cleavage of PARP1 protein CTD PMID:16903866 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO Benomyl results in decreased expression of PLAU mRNA CTD PMID:25530041 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pten phosphatase and tensin homolog increases expression EXP Benomyl results in increased expression of PTEN mRNA CTD PMID:33930522 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP Benomyl results in increased expression of RELA mRNA CTD PMID:33930522 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Benomyl results in decreased expression of SCD1 mRNA CTD PMID:15885261 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO Benomyl results in increased expression of SERPINE2 mRNA CTD PMID:25530041 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Sh2d4a SH2 domain containing 4A increases expression EXP Benomyl results in increased expression of SH2D4A mRNA CTD PMID:15885261 NCBI chr16:21,339,010...21,409,360
Ensembl chr16:21,340,015...21,409,260
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Benomyl results in increased expression of TIMP1 mRNA CTD PMID:25530041 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO Benomyl results in increased expression of TIMP2 mRNA CTD PMID:25530041 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tnf tumor necrosis factor decreases expression EXP Benomyl results in decreased expression of TNF mRNA CTD PMID:33930522 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 affects activity ISO Benomyl affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression
multiple interactions
ISO Benomyl results in increased expression of TSLP mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of TSLP mRNA]
CTD PMID:27784618 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO Benomyl results in increased activity of and results in increased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions EXP Benomyl inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein]; Benomyl inhibits the reaction [Pentaerythritol Tetranitrate results in increased phosphorylation of VASP protein] CTD PMID:15331769 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
carbendazim term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 increases expression EXP carbendazim results in increased expression of ABI2 mRNA CTD PMID:22952946 NCBI chr 9:61,827,186...61,905,703
Ensembl chr 9:61,827,139...61,905,699
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO carbendazim results in increased expression of ACACA mRNA CTD PMID:26071454 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP [carbendazim co-treated with mancozeb] results in increased activity of ACHE protein CTD PMID:33217513 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 increases expression ISO carbendazim results in increased expression of AGPAT2 mRNA CTD PMID:26071454 NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects localization
ISO AHR protein affects the reaction [carbendazim results in increased expression of CYP1A1 protein]
carbendazim affects the localization of AHR protein
CTD PMID:27286660 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Alb albumin decreases expression EXP carbendazim results in decreased expression of ALB protein CTD PMID:35437878 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Anxa10 annexin A10 increases expression ISO carbendazim results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648
JBrowse link
G Arg1 arginase 1 decreases expression ISO carbendazim results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Bag1 BAG cochaperone 1 increases expression EXP carbendazim results in increased expression of BAG1 mRNA CTD PMID:22952946 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP carbendazim results in increased expression of BAX mRNA; carbendazim results in increased expression of BAX protein CTD PMID:35437878 PMID:35513110 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP carbendazim results in decreased expression of BCL2 mRNA CTD PMID:35437878 PMID:35513110 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l14 Bcl2-like 14 increases expression EXP carbendazim results in increased expression of BCL2L14 mRNA CTD PMID:22952946 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases activity ISO carbendazim results in increased activity of BUB1B protein CTD PMID:37506866 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases expression
ISO
EXP
carbendazim results in increased activity of CASP3 protein
Chitosan inhibits the reaction [carbendazim results in increased expression of CASP3 protein]
CTD PMID:30851412 PMID:35705592 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase decreases activity
decreases expression
multiple interactions
EXP carbendazim results in decreased activity of CAT protein
carbendazim results in decreased expression of CAT protein
[Chlorpyrifos co-treated with carbendazim] results in decreased activity of CAT protein; Chitosan inhibits the reaction [carbendazim results in decreased expression of CAT protein]
CTD PMID:27268782 PMID:35513110 PMID:35705592 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO carbendazim results in increased expression of CCNB1 protein CTD PMID:37506866 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Clca2 chloride channel accessory 2 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of CLCA2 mRNA CTD PMID:22382377 NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199
JBrowse link
G Cldn11 claudin 11 multiple interactions EXP [carbendazim co-treated with iprodione] results in decreased expression of CLDN11 protein CTD PMID:28576679 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
JBrowse link
G Clu clusterin decreases expression
increases expression
EXP carbendazim results in decreased expression of CLU mRNA
carbendazim results in increased expression of CLU mRNA
CTD PMID:22952946 PMID:27466211 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
ISO carbendazim results in increased activity of CYP19A1 protein
carbendazim results in increased expression of CYP19A1 mRNA
CTD PMID:14691014 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO
EXP
carbendazim results in increased expression of CYP1A1 mRNA; carbendazim results in increased expression of CYP1A1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [carbendazim results in increased expression of CYP1A1 protein]; AHR protein affects the reaction [carbendazim results in increased expression of CYP1A1 protein]; salicylamide inhibits the reaction [carbendazim results in increased expression of CYP1A1 protein]
CTD PMID:10103034 PMID:21784029 PMID:27286660 PMID:32194361 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO carbendazim results in increased expression of CYP1A2 mRNA; carbendazim results in increased expression of CYP1A2 protein CTD PMID:21784029 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO carbendazim results in increased expression of CYP2B6 mRNA CTD PMID:22310298 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO carbendazim results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO carbendazim results in decreased activity of CYP2D6 protein CTD PMID:20183062 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO carbendazim results in increased expression of CYP3A4 mRNA CTD PMID:22310298 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO carbendazim results in decreased expression of CYP7A1 mRNA; carbendazim results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO carbendazim results in increased expression of DGAT1 mRNA CTD PMID:26071454 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 increases expression ISO carbendazim results in increased expression of DGAT2 mRNA CTD PMID:26071454 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dnaaf11 dynein axonemal assembly factor 11 decreases expression EXP carbendazim results in decreased expression of DNAAF11 mRNA CTD PMID:27466211 NCBI chr 7:98,141,525...98,245,906
Ensembl chr 7:98,144,763...98,245,837
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of DPP7 mRNA CTD PMID:22382377 NCBI chr 3:8,165,091...8,169,343
Ensembl chr 3:8,165,091...8,169,355
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
affects localization
EXP
ISO
carbendazim results in decreased expression of ESR1 mRNA
carbendazim affects the localization of ESR1 protein
CTD PMID:28576679 PMID:37506866 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 decreases expression EXP carbendazim results in decreased expression of ESR2 mRNA CTD PMID:28576679 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fabp9 fatty acid binding protein 9 multiple interactions
decreases expression
EXP Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of FABP9 protein]
carbendazim results in decreased expression of FABP9 mRNA; carbendazim results in decreased expression of FABP9 protein
CTD PMID:33965443 NCBI chr 2:91,591,842...91,595,873
Ensembl chr 2:91,592,298...91,595,873
JBrowse link
G Fank1 fibronectin type III and ankyrin repeat domains 1 increases expression EXP carbendazim results in increased expression of FANK1 mRNA CTD PMID:22952946 NCBI chr 1:188,577,512...188,685,501
Ensembl chr 1:188,577,575...188,685,504
JBrowse link
G Foxa2 forkhead box A2 increases expression ISO carbendazim results in increased expression of FOXA2 mRNA CTD PMID:26071454 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
multiple interactions
EXP carbendazim results in decreased expression of FSHB protein
Carnitine inhibits the reaction [carbendazim results in decreased expression of FSHB protein]
CTD PMID:33965443 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO carbendazim results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP carbendazim results in increased expression of GFAP protein CTD PMID:35513110 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP [carbendazim co-treated with iprodione] results in decreased expression of GJA1 protein CTD PMID:28576679 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases secretion
multiple interactions
EXP carbendazim results in increased secretion of GOT1 protein
Chitosan inhibits the reaction [carbendazim results in increased secretion of GOT1 protein]
CTD PMID:35705592 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
increases secretion
multiple interactions
EXP carbendazim results in increased expression of GPT protein
carbendazim results in increased secretion of GPT protein
Chitosan inhibits the reaction [carbendazim results in increased secretion of GPT protein]
CTD PMID:35437878 PMID:35705592 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
EXP Chitosan inhibits the reaction [carbendazim results in decreased expression of HMOX1 mRNA] CTD PMID:35705592 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ift81 intraflagellar transport 81 decreases expression EXP carbendazim results in decreased expression of IFT81 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057
JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
EXP Carnitine inhibits the reaction [carbendazim results in decreased expression of IL10 protein] CTD PMID:33965443 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta increases expression ISO
EXP
carbendazim results in increased expression of IL1B mRNA; carbendazim results in increased expression of IL1B protein CTD PMID:26071454 PMID:35513110 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
carbendazim results in increased expression of IL6 mRNA; carbendazim results in increased expression of IL6 protein
Carnitine inhibits the reaction [carbendazim results in increased expression of IL6 protein]
CTD PMID:26071454 PMID:33965443 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO carbendazim results in decreased expression of ITGA5 mRNA CTD PMID:25530041 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO carbendazim results in decreased expression of ITGB1 mRNA CTD PMID:25530041 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
EXP Chitosan inhibits the reaction [carbendazim results in increased expression of KEAP1 mRNA] CTD PMID:35705592 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression
multiple interactions
EXP carbendazim results in decreased expression of LHB protein
Carnitine inhibits the reaction [carbendazim results in decreased expression of LHB protein]
CTD PMID:33965443 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Loxl1 lysyl oxidase-like 1 multiple interactions
increases expression
EXP 2,5-hexanedione promotes the reaction [carbendazim results in increased expression of LOXL1 protein]; [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of LOXL1 mRNA CTD PMID:22382377 NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO carbendazim results in decreased expression of LPL protein CTD PMID:30496565 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Macrod1 mono-ADP ribosylhydrolase 1 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of MACROD1 mRNA CTD PMID:22382377 NCBI chr 1:204,246,238...204,387,027
Ensembl chr 1:204,246,166...204,389,716
JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects localization ISO carbendazim affects the localization of MAPK1 protein modified form CTD PMID:37506866 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects localization ISO carbendazim affects the localization of MAPK3 protein modified form CTD PMID:37506866 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression EXP carbendazim results in increased expression of MAPK8 mRNA CTD PMID:35513110 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression EXP carbendazim results in increased expression of MFAP3L mRNA CTD PMID:22952946 NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863
JBrowse link
G Mir128-1 microRNA 128-1 increases expression EXP carbendazim results in increased expression of MIR128-1 mRNA CTD PMID:32418910 NCBI chr13:39,699,449...39,699,530
Ensembl chr13:39,699,449...39,699,530
JBrowse link
G Mir423 microRNA 423 increases expression EXP carbendazim results in increased expression of MIR423 mRNA CTD PMID:32418910 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO carbendazim results in decreased expression of MMP2 mRNA CTD PMID:25530041 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO carbendazim results in decreased expression of MMP9 mRNA CTD PMID:25530041 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP [Chlorpyrifos co-treated with carbendazim] results in increased activity of MPO protein
carbendazim results in increased activity of MPO protein
CTD PMID:27268782 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
decreases expression
ISO
EXP
carbendazim results in increased expression of NFE2L2 protein
Chitosan inhibits the reaction [carbendazim results in decreased expression of NFE2L2 mRNA]
CTD PMID:30851412 PMID:35705592 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression
EXP Carnitine inhibits the reaction [carbendazim results in increased expression of NOS2 protein]; Chitosan inhibits the reaction [carbendazim results in increased expression of NOS2 protein] CTD PMID:33965443 PMID:35705592 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO carbendazim inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Ocln occludin decreases expression
multiple interactions
EXP carbendazim results in decreased expression of OCLN protein
Carnitine inhibits the reaction [carbendazim results in decreased expression of OCLN protein]
CTD PMID:33965443 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression EXP carbendazim results in increased expression of PIM1 mRNA CTD PMID:22952946 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO carbendazim results in decreased expression of PLAU mRNA CTD PMID:25530041 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression EXP carbendazim results in decreased expression of PTGDS mRNA CTD PMID:22952946 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression ISO carbendazim results in increased expression of PTTG1 protein CTD PMID:37506866 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression
multiple interactions
EXP carbendazim results in increased expression of RELA protein
Carnitine inhibits the reaction [carbendazim results in increased expression of RELA protein]
CTD PMID:33965443 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO carbendazim results in increased expression of SERPINE2 mRNA CTD PMID:25530041 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] affects the expression of SHANK3 mRNA CTD PMID:22382377 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
JBrowse link
G Sil1 SIL1 nucleotide exchange factor decreases expression EXP carbendazim results in decreased expression of SIL1 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr18:26,872,423...27,104,365
Ensembl chr18:26,872,429...27,104,332
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP carbendazim results in increased expression of SOD3 mRNA CTD PMID:27466211 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO carbendazim results in increased expression of SREBF1 mRNA CTD PMID:26071454 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions
EXP carbendazim results in decreased expression of STAR mRNA; carbendazim results in decreased expression of STAR protein
Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR mRNA]; Carnitine inhibits the reaction [carbendazim results in decreased expression of STAR protein]
CTD PMID:33965443 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Tbc1d5 TBC1 domain family, member 5 decreases expression EXP carbendazim results in decreased expression of TBC1D5 mRNA CTD PMID:27466211 NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO carbendazim results in increased expression of TIMP1 mRNA CTD PMID:25530041 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO carbendazim results in increased expression of TIMP2 mRNA CTD PMID:25530041 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP Carnitine inhibits the reaction [carbendazim results in increased expression of TNF protein] CTD PMID:33965443 PMID:35437878 PMID:35513110 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnp1 transition protein 1 increases expression EXP carbendazim results in increased expression of TNP1 mRNA CTD PMID:28576679 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274
JBrowse link
G Tnp2 transition protein 2 increases expression EXP carbendazim results in increased expression of TNP2 mRNA CTD PMID:28576679 NCBI chr10:4,879,812...4,880,540
Ensembl chr10:4,879,812...4,880,538
JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity
EXP
ISO
carbendazim results in increased expression of TP53 mRNA
carbendazim affects the activity of TP53 protein
CTD PMID:35435491 PMID:35513110 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression EXP carbendazim results in increased expression of TSHB protein CTD PMID:33965443 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
diethofencarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO diethofencarb binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
propamocarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO propamocarb results in decreased expression of ACACA mRNA CTD PMID:29137890 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ache acetylcholinesterase decreases expression ISO propamocarb results in decreased expression of ACHE protein CTD PMID:30251769 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acly ATP citrate lyase decreases expression ISO propamocarb results in decreased expression of ACLY mRNA CTD PMID:29137890 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO propamocarb results in decreased expression of ACOX1 mRNA CTD PMID:29137890 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD36 protein]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMGCR mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMGCS1 mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 protein]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IFNG mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IFNG protein]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL10 mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1A mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1A protein]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B protein]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of LDLR mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of SCARB1 mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TNF mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TNF protein]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VCAM1 mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VCAM1 protein] CTD PMID:34426332 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of CD36 protein] CTD PMID:34426332 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity ISO propamocarb results in increased activity of CYP19A1 protein CTD PMID:11884232 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO propamocarb results in decreased expression of DGAT2 mRNA CTD PMID:29137890 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO propamocarb results in decreased expression of DRD2 mRNA CTD PMID:30251769 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
ISO [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR1 protein
propamocarb results in increased activity of ESR1 protein
CTD PMID:26812056 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity
ISO [fludioxonil co-treated with N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide co-treated with propamocarb] results in increased activity of ESR2 protein
propamocarb results in increased activity of ESR2 protein
CTD PMID:26812056 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fabp2 fatty acid binding protein 2 decreases expression ISO propamocarb results in decreased expression of FABP2 mRNA CTD PMID:29137890 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Fasn fatty acid synthase decreases expression ISO propamocarb results in decreased expression of FASN mRNA CTD PMID:29137890 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Ffar3 free fatty acid receptor 3 decreases expression ISO propamocarb results in decreased expression of FFAR3 mRNA CTD PMID:29137890 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
JBrowse link
G Gk glycerol kinase decreases expression ISO propamocarb results in decreased expression of GK mRNA CTD PMID:29137890 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO propamocarb results in decreased expression of GPAM mRNA CTD PMID:29137890 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
multiple interactions
ISO propamocarb results in increased expression of HMGCR mRNA
propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMGCR mRNA]
CTD PMID:34426332 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression
multiple interactions
ISO propamocarb results in increased expression of HMGCS1 mRNA
propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of HMGCS1 mRNA]; propamocarb promotes the reaction [Dietary Fats results in increased expression of HMGCS1 mRNA]
CTD PMID:34426332 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of ICAM1 protein]; propamocarb promotes the reaction [Dietary Fats results in increased expression of ICAM1 mRNA]
propamocarb results in increased expression of ICAM1 mRNA
CTD PMID:34426332 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO propamocarb results in increased expression of IFNG protein
propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IFNG mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IFNG protein]
CTD PMID:34426332 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 multiple interactions ISO propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL10 mRNA] CTD PMID:34426332 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1A mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1A protein] CTD PMID:34426332 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO propamocarb results in increased expression of IL1B protein
propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL1B protein]; propamocarb promotes the reaction [Dietary Fats results in increased expression of IL1B mRNA]; propamocarb promotes the reaction [Dietary Fats results in increased expression of IL1B protein]
CTD PMID:34426332 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO propamocarb results in increased expression of IL6 mRNA; propamocarb results in increased expression of IL6 protein
propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of IL6 mRNA]; propamocarb promotes the reaction [Dietary Fats results in increased expression of IL6 protein]
CTD PMID:34426332 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of LDLR mRNA] CTD PMID:34426332 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lpl lipoprotein lipase increases expression ISO propamocarb results in increased expression of LPL mRNA CTD PMID:29137890 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression ISO propamocarb results in decreased expression of MLXIPL mRNA CTD PMID:29137890 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO propamocarb results in decreased expression of PKLR mRNA CTD PMID:29137890 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO propamocarb results in decreased expression of PPARG mRNA CTD PMID:29137890 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions
increases expression
ISO propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of SCARB1 mRNA]; propamocarb promotes the reaction [Dietary Fats results in increased expression of SCARB1 mRNA]
propamocarb results in increased expression of SCARB1 mRNA
CTD PMID:34426332 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO propamocarb results in decreased expression of SCD1 mRNA CTD PMID:29137890 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc27a2 solute carrier family 27 member 2 decreases expression ISO propamocarb results in decreased expression of SLC27A2 mRNA CTD PMID:29137890 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO propamocarb results in decreased expression of SREBF1 mRNA CTD PMID:29137890 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO propamocarb results in increased expression of TNF mRNA; propamocarb results in increased expression of TNF protein
[Dietary Fats co-treated with propamocarb] results in increased expression of TNF protein; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TNF mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of TNF protein]; propamocarb promotes the reaction [Dietary Fats results in increased expression of TNF mRNA]
CTD PMID:34426332 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tph2 tryptophan hydroxylase 2 decreases expression ISO propamocarb results in decreased expression of TPH2 mRNA CTD PMID:30251769 NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression
multiple interactions
ISO propamocarb results in increased expression of VCAM1 mRNA
propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VCAM1 mRNA]; propamocarb affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of VCAM1 protein]; propamocarb promotes the reaction [Dietary Fats results in increased expression of VCAM1 mRNA]
CTD PMID:34426332 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
thiophanate-methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC2 mRNA CTD PMID:32745781 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of ABCC3 mRNA CTD PMID:32745781 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ACOX1 mRNA CTD PMID:32736067 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Alb albumin affects binding ISO Thiophanate binds to ALB protein CTD PMID:19121585 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CD36 mRNA CTD PMID:32736067 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CPT1A mRNA CTD PMID:32736067 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP Thiophanate results in increased expression of CYP1A1 protein CTD PMID:10096430 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP Thiophanate results in increased expression of CYP1A2 protein CTD PMID:10096430 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 affects expression EXP Thiophanate affects the expression of CYP2B1 protein CTD PMID:10096430 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2B10 mRNA; [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2B10 mRNA CTD PMID:32736067 PMID:32745781 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of CYP2C55 mRNA CTD PMID:32736067 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of CYP2C29 mRNA CTD PMID:32745781 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Thiophanate results in increased expression of CYP2E1 protein CTD PMID:10096430 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dio1 iodothyronine deiodinase 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of DIO1 mRNA CTD PMID:32745781 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of ECI1 mRNA CTD PMID:32736067 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of GFAP protein CTD PMID:32736067 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of HMGCS2 mRNA CTD PMID:32745781 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
JBrowse link
G Ins1 insulin 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of INS1 protein CTD PMID:32745781 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO NR1I3 protein affects the susceptibility to [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with Thiophanate co-treated with thiacloprid co-treated with Ziram] CTD PMID:29950287 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Ziram co-treated with Thiophanate co-treated with Captan co-treated with Chlorpyrifos co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with thiacloprid] results in increased expression of PDGFRB protein CTD PMID:32736067 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression EXP Thiophanate affects the expression of PTGS2 CTD PMID:28364781 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SLC16A2 mRNA CTD PMID:32745781 NCBI chr  X:68,725,365...68,848,572
Ensembl chr  X:68,723,261...68,848,771
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 multiple interactions ISO [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SULT1B1 mRNA CTD PMID:32745781 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
JBrowse link
G Thrsp thyroid hormone responsive multiple interactions ISO [2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA; [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in decreased expression of THRSP mRNA; Dietary Fats inhibits the reaction [[2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of THRSP mRNA] CTD PMID:32745781 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        pesticide 18092
          fungicide 14053
            carbamate fungicide 206
              3-iodoprop-2-yn-1-yl butylcarbamate 6
              Propamocarb hydrochloride 0
              benthiavalicarb-isopropyl 0
              benzimidazolylcarbamate fungicide + 166
              carbanilate fungicide + 1
              iprovalicarb 0
              picarbutrazox 0
              propamocarb 36
              pyribencarb 0
              thiophanate 0
              thiophanate-methyl 25
              tolprocarb 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            heteroorganic entity 19541
                              organochalcogen compound 19301
                                organooxygen compound 19193
                                  carbon oxoacid 18681
                                    carbamic acid 17605
                                      carbamate ester 7513
                                        carbamate fungicide 206
                                          3-iodoprop-2-yn-1-yl butylcarbamate 6
                                          Propamocarb hydrochloride 0
                                          benthiavalicarb-isopropyl 0
                                          benzimidazolylcarbamate fungicide + 166
                                          carbanilate fungicide + 1
                                          iprovalicarb 0
                                          picarbutrazox 0
                                          propamocarb 36
                                          pyribencarb 0
                                          thiophanate 0
                                          thiophanate-methyl 25
                                          tolprocarb 0
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