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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(S)-fluoxetine hydrochloride
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Accession:CHEBI:86997 term browser browse the term
Definition:A hydrochloride obtained by reaction of (S)-fluoxetine with one equivalent of hydrochloric acid.
Synonyms:exact_synonym: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride
 related_synonym: (+)-fluoxetine hydrochloride;   (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium chloride;   (S)-fluoxetine HCl;   Formula=C17H19ClF3NO;   InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m0./s1;   InChIKey=GIYXAJPCNFJEHY-NTISSMGPSA-N;   SMILES=Cl.CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1
 xref: CAS:114247-06-2
 cyclic_relationship: is_enantiomer_of CHEBI:86996


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fluoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP fluoxetine decreases expression of Slc6a4 mRNA in the dorsal raphe nucleus RGD PMID:15936043 RGD:38549581 NCBI chr10:63,153,656...63,188,377
Ensembl chr10:63,153,651...63,176,463
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Term Annotations click to browse term
  CHEBI ontology 19853
    role 19804
      biological role 19804
        pharmacological role 18855
          neurotransmitter agent 16449
            serotonergic drug 3966
              serotonin uptake inhibitor 3333
                (S)-fluoxetine hydrochloride 1
                  fluoxetine hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      halogen 18145
                        chlorine atom 17955
                          chlorine molecular entity 17955
                            elemental chlorine 8420
                              monoatomic chlorine 8403
                                chloride 8403
                                  chloride salt 8403
                                    organic chloride salt 881
                                      hydrochloride 674
                                        (S)-fluoxetine hydrochloride 1
                                          fluoxetine hydrochloride 1
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