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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(S)-fluoxetine hydrochloride
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Accession:CHEBI:86997 term browser browse the term
Definition:A hydrochloride obtained by reaction of (S)-fluoxetine with one equivalent of hydrochloric acid.
Synonyms:exact_synonym: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride
 related_synonym: (+)-fluoxetine hydrochloride;   (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium chloride;   (S)-fluoxetine HCl;   Formula=C17H19ClF3NO;   InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m0./s1;   InChIKey=GIYXAJPCNFJEHY-NTISSMGPSA-N;   SMILES=Cl.CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1
 xref: CAS:114247-06-2
 cyclic_relationship: is_enantiomer_of CHEBI:86996


show annotations for term's descendants           Sort by:
fluoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP fluoxetine decreases expression of Slc6a4 mRNA in the dorsal raphe nucleus RGD PMID:15936043 RGD:38549581 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      biological role 20818
        pharmacological role 19911
          neurotransmitter agent 16947
            serotonergic drug 4420
              serotonin uptake inhibitor 3544
                (S)-fluoxetine hydrochloride 1
                  fluoxetine hydrochloride 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      halogen 19194
                        chlorine atom 18961
                          chlorine molecular entity 18961
                            elemental chlorine 10247
                              monoatomic chlorine 10234
                                chloride 10234
                                  chloride salt 10234
                                    organic chloride salt 1119
                                      hydrochloride 749
                                        (S)-fluoxetine hydrochloride 1
                                          fluoxetine hydrochloride 1
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