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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(R)-fluoxetine(1+)
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Accession:CHEBI:86993 term browser browse the term
Definition:An organic cation resulting from the protonation of the amino group of (R)-fluoxetine.
Synonyms:related_synonym: (+)-fluoxetine(1+);   (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium
 xref: Reaxys:25263171
 chemrof_formula: C17H19F3NO
 chemrof_smiles: C[NH2+]CC[C@@H](Oc1ccc(C(F)(F)F)cc1)c1ccccc1
 chemrof_inchi: InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/p+1/t16-/m1/s1
 chemrof_inchikey: RTHCYVBBDHJXIQ-MRXNPFEDSA-O
 cyclic_relationship: is_conjugate_acid_of CHEBI:86991;   is_enantiomer_of CHEBI:86995


show annotations for term's descendants           Sort by:
fluoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP fluoxetine decreases expression of Slc6a4 mRNA in the dorsal raphe nucleus RGD PMID:15936043 RGD:38549581 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      molecular entity 20871
        ion 17463
          organic ion 11556
            organic cation 9047
              (R)-fluoxetine(1+) 1
                (R)-fluoxetine hydrochloride + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      p-block molecular entity 20796
                        carbon group molecular entity 20724
                          organic molecular entity 20706
                            organic ion 11556
                              organic cation 9047
                                (R)-fluoxetine(1+) 1
                                  (R)-fluoxetine hydrochloride + 1
paths to the root