Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(R)-fluoxetine(1+)
go back to main search page
Accession:CHEBI:86993 term browser browse the term
Definition:An organic cation resulting from the protonation of the amino group of (R)-fluoxetine.
Synonyms:exact_synonym: (3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium
 related_synonym: (+)-fluoxetine(1+);   Formula=C17H19F3NO;   InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/p+1/t16-/m1/s1;   InChIKey=RTHCYVBBDHJXIQ-MRXNPFEDSA-O;   SMILES=C[NH2+]CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1
 xref: Reaxys:25263171
 cyclic_relationship: is_conjugate_acid_of CHEBI:86991;   is_enantiomer_of CHEBI:86995



show annotations for term's descendants           Sort by:
fluoxetine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP fluoxetine decreases expression of Slc6a4 mRNA in the dorsal raphe nucleus RGD PMID:15936043 RGD:38549581 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19740
    chemical entity 19738
      molecular entity 19738
        ion 16464
          organic ion 9257
            organic cation 8211
              (R)-fluoxetine(1+) 1
                (R)-fluoxetine hydrochloride + 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    main group molecular entity 19686
                      s-block molecular entity 19541
                        hydrogen molecular entity 19534
                          hydrides 19019
                            inorganic hydride 17950
                              pnictogen hydride 17935
                                nitrogen hydride 17832
                                  ammonium 8300
                                    ammonium ion derivative 8296
                                      (R)-fluoxetine(1+) 1
                                        (R)-fluoxetine hydrochloride + 1
paths to the root