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ONTOLOGY REPORT - ANNOTATIONS


Term:(S)-fluoxetine
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Accession:CHEBI:86992 term browser browse the term
Definition:An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine].
Synonyms:exact_synonym: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
 related_synonym: (-)-fluoxetine;   (S)-N-methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine;   (S)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine;   (S)-N-methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine;   (S)-N-methyl-gamma-(4-trifluoromethylphenoxy)-3-phenylpropylamine;   (S)-Prozac;   Formula=C17H18F3NO;   InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/t16-/m0/s1;   InChIKey=RTHCYVBBDHJXIQ-INIZCTEOSA-N;   SMILES=CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1
 xref: PMID:19144769 "Europe PMC";   PMID:19788198 "Europe PMC";   PMID:20663810 "Europe PMC";   PMID:22903652 "Europe PMC";   PMID:22923967 "Europe PMC";   PMID:23885544 "Europe PMC";   PMID:24464553 "Europe PMC";   PMID:24997906 "Europe PMC";   Reaxys:4356433 "Reaxys"
 cyclic_relationship: is_conjugate_base_of CHEBI:86995;   is_enantiomer_of CHEBI:86991


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fluoxetine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aak1 AP2 associated kinase 1 JBrowse link 4 118,653,851 118,806,796 RGD:6480464
G Aanat aralkylamine N-acetyltransferase JBrowse link 10 105,568,091 105,572,407 RGD:6480464
G Acp5 acid phosphatase 5, tartrate resistant JBrowse link 8 23,142,733 23,149,067 RGD:6480464
G Adam10 ADAM metallopeptidase domain 10 JBrowse link 8 77,107,355 77,237,483 RGD:6480464
G Adarb1 adenosine deaminase, RNA-specific, B1 JBrowse link 20 11,972,352 12,101,022 RGD:6480464
G Adcy8 adenylate cyclase 8 JBrowse link 7 105,353,883 105,593,372 RGD:6480464
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:6480464
G Amelx amelogenin, X-linked JBrowse link X 26,439,197 26,450,495 RGD:6480464
G Ampd2 adenosine monophosphate deaminase 2 JBrowse link 2 210,861,624 210,874,348 RGD:6480464
G Ano3 anoctamin 3 JBrowse link 3 101,843,516 102,203,368 RGD:6480464
G Anp32a acidic nuclear phosphoprotein 32 family member A JBrowse link 8 67,295,578 67,333,075 RGD:6480464
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:6480464
G Anxa5 annexin A5 JBrowse link 2 123,162,477 123,194,730 RGD:6480464
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 JBrowse link 12 22,665,128 22,676,079 RGD:6480464
G Aqp3 aquaporin 3 (Gill blood group) JBrowse link 5 57,423,735 57,429,252 RGD:6480464
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:6480464
G Arl4d ADP-ribosylation factor like GTPase 4D JBrowse link 10 89,577,556 89,580,368 RGD:6480464
G Arntl aryl hydrocarbon receptor nuclear translocator-like JBrowse link 1 178,039,002 178,137,469 RGD:6480464
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:6480464
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:6480464
G Asah1 N-acylsphingosine amidohydrolase 1 JBrowse link 16 53,998,604 54,030,006 RGD:6480464
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:6480464
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:6480464
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:6480464
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:6480464
G Baiap2 BAR/IMD domain containing adaptor protein 2 JBrowse link 10 109,107,326 109,187,458 RGD:6480464
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Bdnf brain-derived neurotrophic factor JBrowse link 3 100,768,637 100,819,216 RGD:6480464
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6480464
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like JBrowse link 1 213,602,836 213,606,507 RGD:6480464
G Bmpr2 bone morphogenetic protein receptor type 2 JBrowse link 9 66,568,074 66,683,019 RGD:6480464
G Brs3 bombesin receptor subtype 3 JBrowse link X 159,484,953 159,510,944 RGD:6480464
G C1ql3 complement C1q like 3 JBrowse link 17 80,314,186 80,320,681 RGD:6480464
G Cacna1g calcium voltage-gated channel subunit alpha1 G JBrowse link 10 82,129,071 82,197,828 RGD:6480464
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:6480464
G Camk4 calcium/calmodulin-dependent protein kinase IV JBrowse link 18 25,746,878 25,975,962 RGD:6480464
G Cartpt CART prepropeptide JBrowse link 2 30,125,249 30,127,408 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cck cholecystokinin JBrowse link 8 130,120,525 130,127,515 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6480464
G Ccn3 cellular communication network factor 3 JBrowse link 7 94,375,134 94,382,154 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccnd3 cyclin D3 JBrowse link 9 15,404,816 15,410,905 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Ccng2 cyclin G2 JBrowse link 14 16,267,572 16,276,068 RGD:6480464
G Cd8a CD8a molecule JBrowse link 4 99,217,640 99,243,352 RGD:6480464
G Cdk5 cyclin-dependent kinase 5 JBrowse link 4 7,282,945 7,287,427 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:6480464
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:6480464
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:6480464
G Cdx1 caudal type homeo box 1 JBrowse link 18 56,337,485 56,355,477 RGD:6480464
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit JBrowse link 8 59,561,817 59,590,172 RGD:6480464
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit JBrowse link 8 59,610,489 59,629,073 RGD:6480464
G Cks1b CDC28 protein kinase regulatory subunit 1B JBrowse link 2 188,740,564 188,745,144 RGD:6480464
G Clock clock circadian regulator JBrowse link 14 34,418,226 34,502,218 RGD:6480464
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 JBrowse link X 39,711,001 39,953,860 RGD:6480464
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:6480464
G Creb1 cAMP responsive element binding protein 1 JBrowse link 9 71,229,753 71,298,994 RGD:6480464
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:6480464
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:6480464
G Cry1 cryptochrome circadian regulator 1 JBrowse link 7 24,534,593 24,634,098 RGD:6480464
G Cry2 cryptochrome circadian regulator 2 JBrowse link 3 81,314,151 81,344,143 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Ctsk cathepsin K JBrowse link 2 196,655,469 196,666,447 RGD:6480464
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 JBrowse link 4 116,261,796 116,278,615 RGD:6480464
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 JBrowse link 1 257,676,172 258,004,428 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 JBrowse link 7 123,651,827 123,655,896 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 JBrowse link 12 19,074,288 19,114,491 RGD:6480464
G Dab1 DAB adaptor protein 1 JBrowse link 5 123,154,360 124,279,170 RGD:6480464
G Dap death-associated protein JBrowse link 2 84,275,884 84,328,998 RGD:6480464
G Dbh dopamine beta-hydroxylase JBrowse link 3 5,709,236 5,731,895 RGD:6480464
G Dclk1 doublecortin-like kinase 1 JBrowse link 2 144,646,255 144,939,389 RGD:6480464
G Ddn dendrin JBrowse link 7 140,479,707 140,486,093 RGD:6480464
G Depp1 DEPP1, autophagy regulator JBrowse link 4 148,780,330 148,784,566 RGD:6480464
G Dio3 iodothyronine deiodinase 3 JBrowse link 6 134,627,278 134,629,139 RGD:6480464
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 JBrowse link 19 22,569,999 22,588,143 RGD:6480464
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 6 64,165,913 64,170,122 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:6480464
G Dusp5 dual specificity phosphatase 5 JBrowse link 1 274,245,184 274,258,595 RGD:6480464
G Dusp8 dual specificity phosphatase 8 JBrowse link 1 215,030,429 215,043,111 RGD:6480464
G Eef2 eukaryotic translation elongation factor 2 JBrowse link 7 11,401,501 11,406,771 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Egr3 early growth response 3 JBrowse link 15 51,756,683 51,762,080 RGD:6480464
G Egr4 early growth response 4 JBrowse link 4 117,293,620 117,296,082 RGD:6480464
G Eif4e eukaryotic translation initiation factor 4E JBrowse link 2 243,819,616 243,853,987 RGD:6480464
G Enam enamelin JBrowse link 14 21,194,635 21,219,529 RGD:6480464
G Ephx4 epoxide hydrolase 4 JBrowse link 14 3,360,680 3,389,996 RGD:6480464
G Evi2a ecotropic viral integration site 2A JBrowse link 10 66,870,048 66,873,948 RGD:6480464
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:6480464
G Fgf1 fibroblast growth factor 1 JBrowse link 18 32,273,830 32,359,831 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Fhl2 four and a half LIM domains 2 JBrowse link 9 49,920,611 49,994,906 RGD:6480464
G Fmod fibromodulin JBrowse link 13 50,874,886 50,885,503 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 80,214,691 80,221,417 RGD:6480464
G Gabrd gamma-aminobutyric acid type A receptor delta subunit JBrowse link 5 172,797,478 172,809,374 RGD:6480464
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480464
G Gad2 glutamate decarboxylase 2 JBrowse link 17 89,171,576 89,234,770 RGD:6480464
G Gak cyclin G associated kinase JBrowse link 14 2,100,104 2,174,332 RGD:6480464
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:6480464
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:6480464
G Gdnf glial cell derived neurotrophic factor JBrowse link 2 56,884,181 56,912,964 RGD:6480464
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 JBrowse link 1 198,199,032 198,209,178 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:6480464
G Glo1 glyoxalase 1 JBrowse link 20 9,273,589 9,291,608 RGD:6480464
G Gna12 G protein subunit alpha 12 JBrowse link 12 15,890,202 15,971,212 RGD:6480464
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:6480464
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:6480464
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:6480464
G Gnb2 G protein subunit beta 2 JBrowse link 12 22,229,079 22,234,096 RGD:6480464
G Gpatch4 G patch domain containing 4 JBrowse link 2 187,404,731 187,424,047 RGD:6480464
G Gpd1 glycerol-3-phosphate dehydrogenase 1 JBrowse link 7 141,368,928 141,377,931 RGD:6480464
G Gpx3 glutathione peroxidase 3 JBrowse link 10 40,247,436 40,255,423 RGD:6480464
G Gramd2b GRAM domain containing 2B JBrowse link 18 51,492,196 51,591,028 RGD:6480464
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:6480464
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:6480464
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:6480464
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Hapln2 hyaluronan and proteoglycan link protein 2 JBrowse link 2 187,395,104 187,402,076 RGD:6480464
G Hdac2 histone deacetylase 2 JBrowse link 20 43,084,870 43,108,198 RGD:6480464
G Hdac5 histone deacetylase 5 JBrowse link 10 90,140,183 90,169,853 RGD:6480464
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:6480464
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:6480464
G Hes7 hes family bHLH transcription factor 7 JBrowse link 10 55,704,485 55,710,523 RGD:6480464
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 JBrowse link 2 52,427,351 52,445,082 RGD:6480464
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:6480464
G Hoxc6 homeo box C6 JBrowse link 7 144,612,230 144,626,036 RGD:6480464
G Hpcal1 hippocalcin-like 1 JBrowse link 6 43,001,920 43,109,083 RGD:6480464
G Hpn hepsin JBrowse link 1 89,534,112 89,549,575 RGD:6480464
G Hpx hemopexin JBrowse link 1 170,423,558 170,431,066 RGD:6480464
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:6480464
G Hspb8 heat shock protein family B (small) member 8 JBrowse link 12 45,905,371 45,920,014 RGD:6480464
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:6480464
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Icam5 intercellular adhesion molecule 5 JBrowse link 8 22,050,222 22,057,209 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Igf2 insulin-like growth factor 2 JBrowse link 1 215,828,102 215,839,081 RGD:6480464
G Igfbp2 insulin-like growth factor binding protein 2 JBrowse link 9 80,118,029 80,144,804 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Inhbe inhibin subunit beta E JBrowse link 7 70,641,423 70,642,848 RGD:6480464
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Itpka inositol-trisphosphate 3-kinase A JBrowse link 3 111,545,007 111,553,605 RGD:6480464
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Kcna3 potassium voltage-gated channel subfamily A member 3 JBrowse link 2 209,766,767 209,768,344 RGD:6480464
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:6480464
G Kcna6 potassium voltage-gated channel subfamily A member 6 JBrowse link 4 159,253,934 159,287,193 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 JBrowse link 3 41,019,898 41,181,070 RGD:6480464
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 JBrowse link 7 120,717,378 120,744,602 RGD:6480464
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 JBrowse link 8 33,435,493 33,463,410 RGD:6480464
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 JBrowse link 11 35,011,007 35,262,362 RGD:6480464
G Kcnk10 potassium two pore domain channel subfamily K member 10 JBrowse link 6 122,417,079 122,549,532 RGD:6480464
G Kcnk2 potassium two pore domain channel subfamily K member 2 JBrowse link 13 107,690,111 107,886,476 RGD:6480464
G Kcnv1 potassium voltage-gated channel modifier subfamily V member 1 JBrowse link 7 84,016,864 84,023,205 RGD:6480464
G Klf10 Kruppel-like factor 10 JBrowse link 7 77,156,010 77,162,096 RGD:6480464
G Klhl24 kelch-like family member 24 JBrowse link 11 84,613,101 84,643,674 RGD:6480464
G L1cam L1 cell adhesion molecule JBrowse link X 156,901,244 156,928,064 RGD:6480464
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:6480464
G Lrg1 leucine-rich alpha-2-glycoprotein 1 JBrowse link 9 10,952,424 10,954,664 RGD:6480464
G Lss lanosterol synthase JBrowse link 20 12,844,522 12,870,474 RGD:6480464
G Map1b microtubule-associated protein 1B JBrowse link 2 29,675,391 29,768,750 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Mbd1 methyl-CpG binding domain protein 1 JBrowse link 18 70,248,568 70,263,190 RGD:6480464
G Mc4r melanocortin 4 receptor JBrowse link 18 62,612,838 62,614,725 RGD:6480464
G Mecp2 methyl CpG binding protein 2 JBrowse link X 156,650,389 156,713,813 RGD:6480464
G Meox1 mesenchyme homeobox 1 JBrowse link 10 89,797,011 89,817,009 RGD:6480464
G Mif macrophage migration inhibitory factor JBrowse link 20 13,715,219 13,732,980 RGD:6480464
G Mixl1 Mix paired-like homeobox 1 JBrowse link 13 97,278,258 97,282,299 RGD:6480464
G Mmp20 matrix metallopeptidase 20 JBrowse link 8 5,823,147 5,875,555 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nanog Nanog homeobox JBrowse link 4 155,531,906 155,539,268 RGD:6480464
G Ncam1 neural cell adhesion molecule 1 JBrowse link 8 53,836,797 54,134,881 RGD:6480464
G Neurod2 neuronal differentiation 2 JBrowse link 10 86,280,865 86,282,681 RGD:6480464
G Nf1 neurofibromin 1 JBrowse link 10 66,732,460 66,928,706 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:6480464
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:6480464
G Npas2 neuronal PAS domain protein 2 JBrowse link 9 45,901,262 46,081,880 RGD:6480464
G Nptx2 neuronal pentraxin 2 JBrowse link 12 12,014,638 12,025,547 RGD:6480464
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:6480464
G Npy1r neuropeptide Y receptor Y1 JBrowse link 16 24,779,480 24,789,131 RGD:6480464
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 JBrowse link 5 151,776,004 151,779,319 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 JBrowse link 19 34,408,275 34,761,003 RGD:6480464
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 JBrowse link 3 43,111,258 43,128,391 RGD:6480464
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:6480464
G Nrgn neurogranin JBrowse link 8 40,015,049 40,023,193 RGD:6480464
G Nrn1 neuritin 1 JBrowse link 17 27,925,054 28,002,946 RGD:6480464
G Ntrk2 neurotrophic receptor tyrosine kinase 2 JBrowse link 17 5,934,651 6,245,778 RGD:6480464
G Nucb1 nucleobindin 1 JBrowse link 1 101,480,160 101,511,029 RGD:6480464
G Nupr1 nuclear protein 1, transcriptional regulator JBrowse link 1 194,767,484 194,769,519 RGD:6480464
G Olig2 oligodendrocyte transcription factor 2 JBrowse link 11 31,389,514 31,392,890 RGD:6480464
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:6480464
G Otx2 orthodenticle homeobox 2 JBrowse link 15 25,500,037 25,511,619 RGD:6480464
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:6480464
G Oxtr oxytocin receptor JBrowse link 4 144,399,326 144,417,598 RGD:6480464
G P4hb prolyl 4-hydroxylase subunit beta JBrowse link 10 109,736,459 109,748,070 RGD:6480464
G Paqr8 progestin and adipoQ receptor family member 8 JBrowse link 9 27,005,270 27,054,591 RGD:6480464
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:6480464
G Pde4a phosphodiesterase 4A JBrowse link 8 22,189,533 22,234,036 RGD:6480464
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:6480464
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:6480464
G Pde8b phosphodiesterase 8B JBrowse link 2 24,718,548 24,955,533 RGD:6480464
G Pdyn prodynorphin JBrowse link 3 122,194,327 122,206,671 RGD:6480464
G Penk proenkephalin JBrowse link 5 17,056,412 17,061,762 RGD:6480464
G Per1 period circadian regulator 1 JBrowse link 10 55,681,761 55,696,557 RGD:6480464
G Per2 period circadian regulator 2 JBrowse link 9 98,555,154 98,597,362 RGD:6480464
G Pla2g4a phospholipase A2 group IVA JBrowse link 13 67,062,252 67,206,688 RGD:6480464
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:6480464
G Plcl1 phospholipase C-like 1 JBrowse link 9 62,016,112 62,349,244 RGD:6480464
G Plec plectin JBrowse link 7 117,230,319 117,291,859 RGD:6480464
G Pmch pro-melanin-concentrating hormone JBrowse link 7 28,655,206 28,656,522 RGD:6480464
G Pomc proopiomelanocortin JBrowse link 6 28,382,937 28,388,771 RGD:6480464
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B JBrowse link 10 86,303,727 86,312,770 RGD:6480464
G Prkcg protein kinase C, gamma JBrowse link 1 64,407,098 64,433,698 RGD:6480464
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Prss23 serine protease 23 JBrowse link 1 153,732,528 153,742,111 RGD:6480464
G Psma3 proteasome 20S subunit alpha 3 JBrowse link 6 93,423,029 93,444,223 RGD:6480464
G Psmb4 proteasome 20S subunit beta 4 JBrowse link 2 196,043,546 196,046,320 RGD:6480464
G Pter phosphotriesterase related JBrowse link 17 80,250,444 80,311,987 RGD:6480464
G Ptgds prostaglandin D2 synthase JBrowse link 3 2,686,125 2,689,059 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:6480464
G Qrfpr pyroglutamylated RFamide peptide receptor JBrowse link 2 122,891,321 122,949,241 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:6480464
G Rgs3 regulator of G-protein signaling 3 JBrowse link 5 78,429,017 78,567,281 RGD:6480464
G Rprml reprimo-like JBrowse link 10 91,710,495 91,711,499 RGD:6480464
G RT1-Ha RT1 class II, locus Ha JBrowse link 20 3,875,478 3,885,140 RGD:6480464
G S100b S100 calcium binding protein B JBrowse link 20 13,130,633 13,142,856 RGD:6480464
G Samd4a sterile alpha motif domain containing 4A JBrowse link 15 23,666,543 23,879,067 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M JBrowse link 6 127,808,785 127,816,067 RGD:6480464
G Serpini1 serpin family I member 1 JBrowse link 2 174,013,058 174,111,693 RGD:6480464
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 1 24,185,451 24,302,309 RGD:6480464
G Slc13a4 solute carrier family 13 member 4 JBrowse link 4 62,796,732 62,841,053 RGD:6480464
G Slc17a7 solute carrier family 17 member 7 JBrowse link 1 101,161,265 101,172,292 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Slc2a3 solute carrier family 2 member 3 JBrowse link 4 155,549,991 155,626,018 RGD:6480464
G Slc30a3 solute carrier family 30 member 3 JBrowse link 6 26,629,752 26,650,106 RGD:6480464
G Slc32a1 solute carrier family 32 member 1 JBrowse link 3 155,102,980 155,107,815 RGD:6480464
G Slc6a15 solute carrier family 6 member 15 JBrowse link 7 45,328,207 45,381,920 RGD:6480464
G Slc6a2 solute carrier family 6 member 2 JBrowse link 19 15,391,682 15,431,274 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464
G Slc6a4 solute carrier family 6 member 4 JBrowse link 10 63,153,656 63,188,377 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464
G Smad1 SMAD family member 1 JBrowse link 19 32,182,942 32,248,694 RGD:6480464
G Smpd1 sphingomyelin phosphodiesterase 1 JBrowse link 1 170,383,682 170,387,525 RGD:6480464
G Snd1 staphylococcal nuclease and tudor domain containing 1 JBrowse link 4 55,772,377 56,171,669 RGD:6480464
G Sox2 SRY-box transcription factor 2 JBrowse link 2 121,165,137 121,167,545 RGD:6480464
G Sp5 Sp5 transcription factor JBrowse link 3 56,766,475 56,769,277 RGD:6480464
G Spry2 sprouty RTK signaling antagonist 2 JBrowse link 15 90,172,769 90,177,823 RGD:6480464
G Sqle squalene epoxidase JBrowse link 7 99,609,929 99,624,803 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Srsf5 serine and arginine rich splicing factor 5 JBrowse link 6 104,611,026 104,640,033 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Stc1 stanniocalcin 1 JBrowse link 15 50,891,137 50,901,791 RGD:6480464
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:6480464
G Syn1 synapsin I JBrowse link X 1,321,315 1,379,202 RGD:6480464
G Syp synaptophysin JBrowse link X 15,694,699 15,709,244 RGD:6480464
G Tagln transgelin JBrowse link 8 50,222,895 50,228,369 RGD:6480464
G Tbx6 T-box transcription factor 6 JBrowse link 1 198,214,797 198,218,706 RGD:6480464
G Tbxt T-box transcription factor T JBrowse link 1 52,887,067 52,900,691 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464
G Tmc4 transmembrane channel-like 4 JBrowse link 1 64,114,687 64,126,576 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfsf11 TNF superfamily member 11 JBrowse link 15 60,482,527 60,512,704 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tph1 tryptophan hydroxylase 1 JBrowse link 1 102,669,868 102,699,442 RGD:6480464
G Tph2 tryptophan hydroxylase 2 JBrowse link 7 58,042,279 58,149,220 RGD:6480464
G Tpm1 tropomyosin 1 JBrowse link 8 72,814,737 72,841,496 RGD:6480464
G Tshb thyroid stimulating hormone subunit beta JBrowse link 2 205,207,799 205,215,199 RGD:6480464
G Tssk2 testis-specific serine kinase 2 JBrowse link 11 87,235,058 87,236,413 RGD:6480464
G Ttr transthyretin JBrowse link 18 15,532,963 15,542,180 RGD:6480464
G Tubb3 tubulin, beta 3 class III JBrowse link 19 56,220,759 56,229,813 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Vgf VGF nerve growth factor inducible JBrowse link 12 22,677,302 22,680,630 RGD:6480464
G Vldlr very low density lipoprotein receptor JBrowse link 1 245,236,819 245,273,688 RGD:6480464
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:6480464
G Wipi1 WD repeat domain, phosphoinositide interacting 1 JBrowse link 10 97,859,730 97,896,949 RGD:6480464
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:6480464
G Xpo1 exportin 1 JBrowse link 14 108,007,421 108,049,088 RGD:6480464
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon JBrowse link 10 63,884,338 63,921,709 RGD:6480464
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta JBrowse link 14 83,053,041 83,062,424 RGD:6480464
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta JBrowse link 7 75,573,553 75,598,295 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        pharmacological role 18684
          neurotransmitter agent 16233
            serotonergic drug 3846
              serotonin uptake inhibitor 3274
                (S)-fluoxetine 323
                  fluoxetine 323
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            organic hydride 17528
                              organic fundamental parent 17528
                                hydrocarbon 16935
                                  alkane 12481
                                    methane 9407
                                      halomethane 9407
                                        fluoromethanes 6272
                                          fluoroform 6272
                                            trifluoromethyl group 6272
                                              (trifluoromethyl)benzenes 6272
                                                N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine 323
                                                  (S)-fluoxetine 323
                                                    fluoxetine 323
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.