Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:stattic
go back to main search page
Accession:CHEBI:86989 term browser browse the term
Definition:A member of the class of 1-benzothiophenes that is 1-benzothiophene-1,1-dioxide substituted at position 6 by a nitro group. Used as a radiosensitising agent for esophageal squamous cell carcinoma.
Synonyms:exact_synonym: 6-nitro-1H-1-benzothiophene-1,1-dione
 related_synonym: 6-nitro-1-benzothiophene 1,1-dioxide;   CHEMBL1337170;   Formula=C8H5NO4S;   InChI=1S/C8H5NO4S/c10-9(11)7-2-1-6-3-4-14(12,13)8(6)5-7/h1-5H;   InChIKey=ZRRGOUHITGRLBA-UHFFFAOYSA-N;   SMILES=[O-][N+](=O)c1ccc2C=CS(=O)(=O)c2c1;   STAT3 Inhibitor V
 xref_mesh: MESH:C517409
 xref: PMID:17114005;   PMID:25425624;   PMID:25492480;   Reaxys:11410


show annotations for term's descendants           Sort by:
stattic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 multiple interactions EXP stattic inhibits the reaction [Arsenicals results in increased phosphorylation of AKT1 protein] CTD PMID:23255093 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP stattic results in decreased expression of BCL2 protein CTD PMID:24627483 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP stattic inhibits the reaction [glycine-extended gastrin 17 results in increased expression of BCL2L1 mRNA] CTD PMID:19153190 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 multiple interactions EXP stattic inhibits the reaction [glycine-extended gastrin 17 results in increased expression of BIRC5 mRNA] CTD PMID:19153190 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G CCN2 cellular communication network factor 2 multiple interactions EXP
ISO		 stattic inhibits the reaction [IL6 protein results in increased expression of CCN2 mRNA]
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA]		 CTD PMID:25740948 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCND1 cyclin D1 multiple interactions ISO
EXP		 stattic inhibits the reaction [EDN1 protein results in increased expression of CCND1 mRNA]; stattic inhibits the reaction [EDN1 protein results in increased expression of CCND1 protein]
stattic affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which affects the expression of CCND1 protein]		 CTD PMID:30670587 PMID:33396024 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474 		JBrowse link
G CD44 CD44 molecule (IN blood group) multiple interactions EXP stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]] CTD PMID:33396024 NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402 		JBrowse link
G CDH1 cadherin 1 multiple interactions EXP stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of CDH1 mRNA]; stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of CDH1 protein]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of CDH1 mRNA]] CTD PMID:33396024 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537 		JBrowse link
G CISH cytokine inducible SH2 containing protein multiple interactions EXP stattic inhibits the reaction [IL6 protein results in increased expression of CISH mRNA] CTD PMID:26297436 NCBI chr 3:50,606,489...50,611,774
Ensembl chr 3:50,606,489...50,611,774 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP
ISO		 stattic inhibits the reaction [IL6 protein results in increased expression of COL1A1 mRNA]
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of COL1A1 mRNA]		 CTD PMID:25740948 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP stattic affects the reaction [CXCL8 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which affects the expression of PCNA protein]]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of CDH1 mRNA]]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CD44 protein]]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 mRNA]]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI2 mRNA]]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TWIST1 mRNA]]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM mRNA]] CTD PMID:33396024 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G EDN1 endothelin 1 multiple interactions ISO stattic inhibits the reaction [EDN1 protein results in increased expression of CCND1 mRNA]; stattic inhibits the reaction [EDN1 protein results in increased expression of CCND1 protein]; stattic inhibits the reaction [EDN1 protein results in increased expression of SKP2 mRNA]; stattic inhibits the reaction [EDN1 protein results in increased expression of SKP2 protein] CTD PMID:30670587 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EGF epidermal growth factor multiple interactions EXP stattic inhibits the reaction [EGF protein results in increased expression of PSMB5 protein]; stattic inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein] CTD PMID:24627483 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions EXP stattic inhibits the reaction [Arsenicals results in increased phosphorylation of EZH2 protein] CTD PMID:23255093 NCBI chr 7:148,807,383...148,884,291
Ensembl chr 7:148,807,257...148,884,321 		JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO stattic inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein] CTD PMID:28887131 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha multiple interactions EXP stattic inhibits the reaction [IL6 protein results in increased expression of HIF1A mRNA]; stattic inhibits the reaction [IL6 protein results in increased expression of HIF1A protein] CTD PMID:29341321 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 multiple interactions EXP stattic inhibits the reaction [Particulate Matter results in increased expression of ICAM1 protein] CTD PMID:29329563 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IL12A interleukin 12A multiple interactions EXP stattic inhibits the reaction [IL6 protein results in increased expression of IL12A mRNA] CTD PMID:26297436 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO stattic inhibits the reaction [deoxynivalenol results in increased expression of IL1B mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL1B mRNA] CTD PMID:22454431 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 multiple interactions EXP
ISO		 [stattic co-treated with IL6 protein] results in increased expression of SOCS3 protein; stattic affects the reaction [IL6 protein affects the phosphorylation of STAT3 protein]; stattic inhibits the reaction [IL6 protein results in increased activity of TGFB1 protein]; stattic inhibits the reaction [IL6 protein results in increased expression of APPA mRNA]; stattic inhibits the reaction [IL6 protein results in increased expression of CCN2 mRNA]; stattic inhibits the reaction [IL6 protein results in increased expression of CISH mRNA]; stattic inhibits the reaction [IL6 protein results in increased expression of COL1A1 mRNA]; stattic inhibits the reaction [IL6 protein results in increased expression of HIF1A mRNA]; stattic inhibits the reaction [IL6 protein results in increased expression of HIF1A protein]; stattic inhibits the reaction [IL6 protein results in increased expression of IL12A mRNA]; stattic inhibits the reaction [IL6 protein results in increased expression of TGFB1 mRNA]; stattic inhibits the reaction [IL6 protein results in increased expression of TGFB1A mRNA]; stattic inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]
stattic inhibits the reaction [27-hydroxycholesterol results in increased expression of IL6 mRNA]; stattic inhibits the reaction [27-hydroxycholesterol results in increased secretion of IL6 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of IL6 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of IL6 mRNA]		 CTD PMID:22454431 PMID:25740948 PMID:26297436 PMID:28739487 PMID:29341321 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G JAK2 Janus kinase 2 multiple interactions ISO stattic inhibits the reaction [deoxynivalenol results in increased expression of JAK2 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of JAK2 mRNA] CTD PMID:22454431 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948 		JBrowse link
G KRT1 keratin 1 multiple interactions EXP stattic inhibits the reaction [METTL3 protein promotes the reaction [sodium arsenite results in increased expression of KRT1 protein]] CTD PMID:36368553 NCBI chr12:52,674,736...52,680,407
Ensembl chr12:52,674,736...52,680,407 		JBrowse link
G KRT10 keratin 10 multiple interactions EXP stattic inhibits the reaction [METTL3 protein promotes the reaction [sodium arsenite results in increased expression of KRT10 protein]] CTD PMID:36368553 NCBI chr17:40,818,117...40,822,614
Ensembl chr17:40,818,117...40,822,614 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 multiple interactions EXP stattic inhibits the reaction [arsenic trichloride results in increased phosphorylation of MAPK9 protein] CTD PMID:24434654 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099 		JBrowse link
G METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit multiple interactions EXP stattic inhibits the reaction [METTL3 protein promotes the reaction [sodium arsenite results in increased expression of KRT1 protein]]; stattic inhibits the reaction [METTL3 protein promotes the reaction [sodium arsenite results in increased expression of KRT10 protein]]; stattic inhibits the reaction [METTL3 protein promotes the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]] CTD PMID:36368553 NCBI chr14:21,498,138...21,511,340
Ensembl chr14:21,498,133...21,511,342 		JBrowse link
G MIR21 microRNA 21 affects expression
multiple interactions		 EXP stattic affects the expression of MIR21 mRNA
stattic affects the reaction [arsenic trichloride affects the expression of MIR21 mRNA]		 CTD PMID:24434654 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MMP10 matrix metallopeptidase 10 decreases expression EXP stattic results in decreased expression of MMP10 mRNA CTD PMID:22285823 NCBI chr11:102,770,502...102,780,628
Ensembl chr11:102,770,502...102,780,628 		JBrowse link
G MPO myeloperoxidase multiple interactions ISO stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:25740948 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G PCNA proliferating cell nuclear antigen multiple interactions EXP stattic affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which affects the expression of PCNA protein]; stattic affects the reaction [CXCL8 protein affects the reaction [[sodium arsenite results in increased abundance of Arsenic] which affects the expression of PCNA protein]] CTD PMID:33396024 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PSMB1 proteasome 20S subunit beta 1 decreases expression EXP stattic results in decreased expression of PSMB1 mRNA; stattic results in decreased expression of PSMB1 protein CTD PMID:24627483 NCBI chr 6:170,535,120...170,553,307
Ensembl chr 6:170,535,120...170,553,307 		JBrowse link
G PSMB2 proteasome 20S subunit beta 2 decreases expression EXP stattic results in decreased expression of PSMB2 mRNA; stattic results in decreased expression of PSMB2 protein CTD PMID:24627483 NCBI chr 1:35,599,541...35,641,526
Ensembl chr 1:35,599,541...35,641,526 		JBrowse link
G PSMB3 proteasome 20S subunit beta 3 decreases expression EXP stattic results in decreased expression of PSMB3 mRNA; stattic results in decreased expression of PSMB3 protein CTD PMID:24627483 NCBI chr17:38,752,741...38,764,225
Ensembl chr17:38,752,741...38,764,225 		JBrowse link
G PSMB4 proteasome 20S subunit beta 4 decreases expression EXP stattic results in decreased expression of PSMB4 mRNA; stattic results in decreased expression of PSMB4 protein CTD PMID:24627483 NCBI chr 1:151,399,573...151,401,937
Ensembl chr 1:151,399,560...151,401,937 		JBrowse link
G PSMB5 proteasome 20S subunit beta 5 decreases expression
multiple interactions		 EXP stattic results in decreased expression of PSMB5 mRNA; stattic results in decreased expression of PSMB5 protein
stattic inhibits the reaction [EGF protein results in increased expression of PSMB5 protein]		 CTD PMID:24627483 NCBI chr14:23,025,851...23,035,220
Ensembl chr14:23,016,543...23,035,230 		JBrowse link
G PSMB6 proteasome 20S subunit beta 6 decreases expression EXP stattic results in decreased expression of PSMB6 mRNA; stattic results in decreased expression of PSMB6 protein CTD PMID:24627483 NCBI chr17:4,796,164...4,798,495
Ensembl chr17:4,796,144...4,798,502 		JBrowse link
G PSMB7 proteasome 20S subunit beta 7 decreases expression EXP stattic results in decreased expression of PSMB7 mRNA; stattic results in decreased expression of PSMB7 protein CTD PMID:24627483 NCBI chr 9:124,353,465...124,415,442
Ensembl chr 9:124,353,465...124,415,444 		JBrowse link
G RIOX2 ribosomal oxygenase 2 multiple interactions EXP stattic inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 mRNA]; stattic inhibits the reaction [arsenic trichloride results in increased phosphorylation of RIOX2 protein] CTD PMID:24434654 NCBI chr 3:97,941,818...97,972,431
Ensembl chr 3:97,941,818...97,972,457 		JBrowse link
G SKP2 S-phase kinase associated protein 2 multiple interactions ISO stattic inhibits the reaction [EDN1 protein results in increased expression of SKP2 mRNA]; stattic inhibits the reaction [EDN1 protein results in increased expression of SKP2 protein] CTD PMID:30670587 NCBI chr 5:36,152,111...36,193,530
Ensembl chr 5:36,151,989...36,196,849 		JBrowse link
G SNAI1 snail family transcriptional repressor 1 multiple interactions EXP stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 mRNA]; stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 protein]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI1 mRNA]] CTD PMID:33396024 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 multiple interactions EXP stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI2 mRNA]; stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI2 protein]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of SNAI2 mRNA]] CTD PMID:33396024 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 multiple interactions EXP [stattic co-treated with IL6 protein] results in increased expression of SOCS3 protein CTD PMID:25740948 NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions ISO stattic inhibits the reaction [deoxynivalenol results in increased expression of STAT1 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT1 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT1 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT1 protein] CTD PMID:22454431 NCBI chr 2:190,969,149...191,014,171
Ensembl chr 2:190,908,460...191,020,960 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation		 EXP
ISO		 stattic affects the reaction [Arsenicals affects the phosphorylation of STAT3 protein]; stattic affects the reaction [IL6 protein affects the phosphorylation of STAT3 protein]; stattic inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [METTL3 protein promotes the reaction [sodium arsenite results in increased phosphorylation of STAT3 protein]]
Stattic inhibits the reaction [Il-6 increases phosphorylation of STAT3 protein in the stomach)
stattic inhibits the reaction [zoniporide results in increased phosphorylation of STAT3 protein]
stattic inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [deoxynivalenol results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [deoxynivalenol results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [T-2 Toxin results in increased expression of STAT3 mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased phosphorylation of STAT3 protein]; stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased phosphorylation of STAT3 protein]
stattic results in decreased phosphorylation of STAT3 protein		 CTD
RGD		 PMID:20942815 PMID:22454431 PMID:23255093 PMID:24627483 PMID:25740948 More... RGD:127284846 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions EXP
ISO		 stattic inhibits the reaction [IL6 protein results in increased activity of TGFB1 protein]; stattic inhibits the reaction [IL6 protein results in increased expression of TGFB1 mRNA]
stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TGFB1 mRNA]		 CTD PMID:25740948 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO stattic inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; stattic inhibits the reaction [T-2 Toxin results in increased expression of TNF mRNA] CTD PMID:22454431 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 multiple interactions EXP stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TWIST1 mRNA]; stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TWIST1 protein]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TWIST1 mRNA]] CTD PMID:33396024 NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636 		JBrowse link
G VIM vimentin multiple interactions EXP stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM mRNA]; stattic inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM protein]; stattic inhibits the reaction [CXCL8 protein promotes the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of VIM mRNA]] CTD PMID:33396024 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      biological role 25929
        inhibitor 22521
          STAT3 inhibitor 950
            stattic 47
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    p-block element atom 25834
                      carbon group element atom 25434
                        carbon atom 25403
                          organic molecular entity 25392
                            organic molecule 25222
                              organic cyclic compound 24274
                                organic heterocyclic compound 22328
                                  organic heteropolycyclic compound 21329
                                    organic heterobicyclic compound 18570
                                      benzothiophenes 1008
                                        1-benzothiophenes 1008
                                          stattic 47
paths to the root