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ONTOLOGY REPORT - ANNOTATIONS


Term:pyrantel
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Accession:CHEBI:8654 term browser browse the term
Definition:A carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'.
Synonyms:exact_synonym: 1-methyl-2-[(E)-2-(2-thienyl)vinyl]-1,4,5,6-tetrahydropyrimidine
 related_synonym: Formula=C11H14N2S;   InChI=1S/C11H14N2S/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h2,4-6,9H,3,7-8H2,1H3/b6-5+;   InChIKey=YSAUAVHXTIETRK-AATRIKPKSA-N;   SMILES=CN1CCCN=C1\\C=C\\c1cccs1;   pirantel;   pyrantelum
 xref: CAS:15686-83-6 "ChemIDplus";   CAS:15686-83-6 "KEGG COMPOUND";   Drug_Central:2999 "DrugCentral";   KEGG:C07409;   KEGG:D08451
 xref_mesh: MESH:D011715
 xref: PMID:20307935 "Europe PMC";   PMID:21689886 "Europe PMC";   PMID:2619378 "Europe PMC";   PMID:5124439 "Europe PMC";   PMID:552733 "Europe PMC";   PMID:7402460 "Europe PMC";   Patent:BE658987;   Patent:US3502661;   Reaxys:518505 "Reaxys";   Wikipedia:Pyrantel


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pyrantel term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      application 19246
        pesticide 15810
          nematicide 3256
            antinematodal drug 448
              pyrantel 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic molecule 19353
                              organic cyclic compound 19102
                                organic heterocyclic compound 18170
                                  organonitrogen heterocyclic compound 16978
                                    tetrahydropyrimidine 1
                                      1,4,5,6-tetrahydropyrimidines 1
                                        pyrantel 1
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