Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:purpurin
go back to main search page
Accession:CHEBI:8645 term browser browse the term
Definition:A trihydroxyanthraquinone derived from anthracene by substitution with oxo groups at C-9 and C-10 and with hydroxy groups at C-1, C-2 and C-4.
Synonyms:exact_synonym: 1,2,4-trihydroxyanthracene-9,10-dione
 related_synonym: 1,2,4-Trihydroxyanthrachinon;   1,2,4-trihydroxy-9,10-anthracenedione;   1,2,4-trihydroxy-9,10-anthraquinone;   1,2,4-trihydroxyanthra-9,10-quinone;   1,2,4-trihydroxyanthraquinone;   Alizarin purpurin;   C.I. 58205;   Formula=C14H8O5;   InChI=1S/C14H8O5/c15-8-5-9(16)14(19)11-10(8)12(17)6-3-1-2-4-7(6)13(11)18/h1-5,15-16,19H;   InChIKey=BBNQQADTFFCFGB-UHFFFAOYSA-N;   Pr;   SMILES=Oc1cc(O)c2C(=O)c3ccccc3C(=O)c2c1O;   hydroxylizaric acid;   purpurine;   smoke Brown G;   verantin
 xref: Beilstein:1887127;   CAS:81-54-9;   Gmelin:271628;   KEGG:C10395;   KNApSAcK:C00002857
 xref_mesh: MESH:C410870
 xref: PMID:10521685;   PMID:14500876;   PMID:19748496;   PMID:20238054;   PMID:20392152;   PMID:20686243;   PMID:21552598;   PMID:22997839;   PMID:23226409;   PMID:23233879;   PMID:26037779;   PMID:26178874;   Patent:CN101659793;   Reaxys:1887127;   Wikipedia:1\,2\,4-Trihydroxyanthraquinone

show annotations for term's descendants           Sort by:
 
purpurin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
increases activity		 ISO purpurin results in decreased activity of CYP1A1 protein
purpurin results in increased expression of CYP1A1 mRNA
purpurin results in increased activity of CYP1A1 protein		 CTD PMID:11502733, PMID:12379470, PMID:12744663 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases activity		 ISO purpurin results in decreased activity of CYP1A2 protein
purpurin results in increased activity of CYP1A2 protein		 CTD PMID:12379470, PMID:12744663 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
increases expression		 ISO purpurin results in decreased activity of CYP1B1 protein
purpurin results in increased expression of CYP1B1 mRNA		 CTD PMID:11502733, PMID:12379470 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases activity ISO purpurin results in increased activity of CYP2B1 protein CTD PMID:12744663 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO purpurin results in decreased activity of CYP2E1 protein CTD PMID:12379470 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
increases activity		 ISO 3-amino-1-methyl-5H-pyrido(4,3-b)indole promotes the reaction [purpurin results in increased activity of POR protein] CTD PMID:12744663 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biophysical role 12283
          biological pigment 1045
            purpurin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      ketone 16144
                                        cyclic ketone 13813
                                          quinone 8338
                                            acenoquinone 7497
                                              anthraquinone 469
                                                hydroxyanthraquinones 461
                                                  trihydroxyanthraquinone 207
                                                    purpurin 6
paths to the root

Contact Us |  About Us |  License CC BY 4.0 |  Legal Disclaimer |  © Medical College of Wisconsin
NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.