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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:manganese(II) sulfate
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Accession:CHEBI:86360 term browser browse the term
Definition:A metal sulfate in which the metal component is manganese in the +2 oxidation state.
Synonyms:related_synonym: Formula=MnO4S;   InChI=1S/Mn.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2;   InChIKey=SQQMAOCOWKFBNP-UHFFFAOYSA-L;   Manganese monosulfate;   Manganese sulfate anhydrous;   Manganese sulphate;   Manganous sulfate;   MnSO4;   SMILES=[Mn++].[O-]S([O-])(=O)=O;   manganese(2+) sulfate;   manganese(2+) sulphate;   manganese(II) sulphate
 xref: CAS:7785-87-7
 xref_mesh: MESH:C039798
 xref: MetaCyc:CPD0-1608;   Reaxys:11343137;   Reaxys:14270535;   Reaxys:28059988;   Wikipedia:Manganese(II)_sulfate

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manganese(II) sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression EXP manganese sulfate results in increased expression of CXCL2 mRNA CTD PMID:11708899 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP manganese sulfate results in decreased expression of GLUL mRNA; manganese sulfate results in decreased expression of GLUL protein CTD PMID:16943606 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression EXP manganese sulfate results in increased expression of HSPA4 mRNA CTD PMID:26097037 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO Lipopolysaccharides promotes the reaction [manganese sulfate results in increased expression of IL6 protein]; manganese sulfate promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:15601679 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807 		JBrowse link
G Mt1 metallothionein 1 decreases expression EXP manganese sulfate results in decreased expression of MT1A mRNA CTD PMID:12387356 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724 		JBrowse link
G Nos1 nitric oxide synthase 1 decreases expression EXP manganese sulfate results in decreased expression of NOS1 mRNA CTD PMID:16476481 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP manganese sulfate results in decreased expression of SLC1A3 mRNA CTD PMID:12387356 NCBI chr 2:57,860,881...57,935,363
Ensembl chr 2:57,860,834...57,935,363 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression EXP manganese sulfate results in decreased expression of TGFB1 mRNA CTD PMID:16476481 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199 		JBrowse link
G Th tyrosine hydroxylase decreases expression EXP manganese sulfate results in decreased expression of TH mRNA CTD PMID:16943606 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO Lipopolysaccharides promotes the reaction [manganese sulfate results in increased expression of TNF protein]; manganese sulfate promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:15601679 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    chemical entity 19853
      molecular entity 19851
        transition element molecular entity 16437
          manganese group molecular entity 1513
            manganese molecular entity 1513
              manganese(II) sulfate 10
                manganese(II) sulfate dihydrate 0
                manganese(II) sulfate hexahydrate 0
                manganese(II) sulfate monohydrate 0
                manganese(II) sulfate pentahydrate 0
                manganese(II) sulfate tetrahydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      chalcogen 19438
                        oxygen atom 19400
                          oxygen molecular entity 19400
                            hydroxides 19123
                              oxoacid 18256
                                chalcogen oxoacid 11493
                                  sulfur oxoacid 11097
                                    sulfuric acid 8017
                                      sulfuric acid derivative 8017
                                        sulfates 8014
                                          sulfate salt 7063
                                            inorganic sulfate salt 7005
                                              metal sulfate 7004
                                                manganese(II) sulfate 10
                                                  manganese(II) sulfate dihydrate 0
                                                  manganese(II) sulfate hexahydrate 0
                                                  manganese(II) sulfate monohydrate 0
                                                  manganese(II) sulfate pentahydrate 0
                                                  manganese(II) sulfate tetrahydrate 0
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