CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: manganese(II) sulfate
Accession: CHEBI:86360
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Definition: A metal sulfate in which the metal component is manganese in the +2 oxidation state.
Synonyms: related_synonym: Formula=MnO4S; InChI=1S/Mn.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2; InChIKey=SQQMAOCOWKFBNP-UHFFFAOYSA-L; Manganese monosulfate; Manganese sulfate anhydrous; Manganese sulphate; Manganous sulfate; MnSO4; SMILES=[Mn++].[O-]S([O-])(=O)=O; manganese(2+) sulfate; manganese(2+) sulphate; manganese(II) sulphate
xref: CAS:7785-87-7
xref_mesh: MESH:C039798
xref: MetaCyc:CPD0-1608; Reaxys:11343137; Reaxys:14270535; Reaxys:28059988; Wikipedia:Manganese(II)_sulfate
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Cxcl2
chemokine (C-X-C motif) ligand 2
increases expression
ISO
manganese sulfate results in increased expression of CXCL2 mRNA
CTD
PMID:11708899
NCBI chr 5:90,903,899...90,905,938
Ensembl chr 5:90,903,871...90,905,938
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Glul
glutamate-ammonia ligase (glutamine synthetase)
decreases expression
ISO
manganese sulfate results in decreased expression of GLUL mRNA; manganese sulfate results in decreased expression of GLUL protein
CTD
PMID:16943606
NCBI chr 1:153,899,929...153,909,723
Ensembl chr 1:153,899,944...153,909,723
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Hspa4
heat shock protein 4
increases expression
ISO
manganese sulfate results in increased expression of HSPA4 mRNA
CTD
PMID:26097037
NCBI chr11:53,259,814...53,300,479
Ensembl chr11:53,259,814...53,300,457
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Il6
interleukin 6
multiple interactions increases expression
EXP
Lipopolysaccharides promotes the reaction [manganese sulfate results in increased expression of IL6 protein]; manganese sulfate promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD
PMID:15601679
NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
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Mt1
metallothionein 1
decreases expression
ISO
manganese sulfate results in decreased expression of MT1A mRNA
CTD
PMID:12387356
NCBI chr 8:94,178,883...94,180,327
Ensembl chr 8:94,179,082...94,180,327
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Nos1
nitric oxide synthase 1, neuronal
decreases expression
ISO
manganese sulfate results in decreased expression of NOS1 mRNA
CTD
PMID:16476481
NCBI chr 5:117,866,839...117,958,840
Ensembl chr 5:117,781,032...117,958,840
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Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
decreases expression
ISO
manganese sulfate results in decreased expression of SLC1A3 mRNA
CTD
PMID:12387356
NCBI chr15:8,634,124...8,710,807
Ensembl chr15:8,634,124...8,710,764
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Tgfb1
transforming growth factor, beta 1
decreases expression
ISO
manganese sulfate results in decreased expression of TGFB1 mRNA
CTD
PMID:16476481
NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
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Th
tyrosine hydroxylase
decreases expression
ISO
manganese sulfate results in decreased expression of TH mRNA
CTD
PMID:16943606
NCBI chr 7:142,892,779...142,899,995
Ensembl chr 7:142,892,752...142,931,128
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Tnf
tumor necrosis factor
multiple interactions increases expression
EXP
Lipopolysaccharides promotes the reaction [manganese sulfate results in increased expression of TNF protein]; manganese sulfate promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD
PMID:15601679
NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
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