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ONTOLOGY REPORT - ANNOTATIONS


Term:puerarin
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Accession:CHEBI:8633 term browser browse the term
Definition:A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 7 and 4' and a beta-D-glucopyranosyl residue at position 8 via a C-glycosidic linkage.
Synonyms:exact_synonym: (1S)-1,5-anhydro-1-[7-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-8-yl]-D-glucitol
 related_synonym: Formula=C21H20O9;   InChI=1S/C21H20O9/c22-7-14-17(26)18(27)19(28)21(30-14)15-13(24)6-5-11-16(25)12(8-29-20(11)15)9-1-3-10(23)4-2-9/h1-6,8,14,17-19,21-24,26-28H,7H2/t14-,17-,18+,19-,21+/m1/s1;   InChIKey=HKEAFJYKMMKDOR-VPRICQMDSA-N;   SMILES=OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1c(O)ccc2c1occ(-c1ccc(O)cc1)c2=O
 xref: CAS:3681-99-0 "ChemIDplus";   CAS:3681-99-0 "KEGG COMPOUND";   KEGG:C10524;   KNApSAcK:C00006094
 xref_mesh: MESH:C033607
 xref: PMID:25310912 "Europe PMC";   PMID:25553536 "Europe PMC";   Reaxys:64198 "Reaxys"


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puerarin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACHE acetylcholinesterase (Cartwright blood group) JBrowse link 7 100,889,994 100,896,994 RGD:6480464
G ACLY ATP citrate lyase JBrowse link 17 41,866,916 41,930,542 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G ALB albumin JBrowse link 4 73,404,287 73,421,482 RGD:6480464
G AQP1 aquaporin 1 (Colton blood group) JBrowse link 7 30,911,694 30,925,517 RGD:6480464
G AQP3 aquaporin 3 (Gill blood group) JBrowse link 9 33,441,154 33,447,596 RGD:6480464
G AR androgen receptor JBrowse link X 67,544,021 67,730,619 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BIRC5 baculoviral IAP repeat containing 5 JBrowse link 17 78,214,253 78,225,635 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP8 caspase 8 JBrowse link 2 201,233,443 201,287,711 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CDH1 cadherin 1 JBrowse link 16 68,737,292 68,835,537 RGD:6480464
G COL3A1 collagen type III alpha 1 chain JBrowse link 2 188,974,373 189,012,746 RGD:6480464
G CREB1 cAMP responsive element binding protein 1 JBrowse link 2 207,529,943 207,605,988 RGD:6480464
G CYGB cytoglobin JBrowse link 17 76,527,356 76,557,692 RGD:6480464
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 10 133,527,363 133,539,123 RGD:6480464
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 8 58,490,178 58,500,163 RGD:6480464
G DSG3 desmoglein 3 JBrowse link 18 31,447,741 31,478,712 RGD:6480464
G EGF epidermal growth factor JBrowse link 4 109,912,883 110,013,766 RGD:6480464
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 38,030,534 38,060,365 RGD:6480464
G ESR1 estrogen receptor 1 JBrowse link 6 151,654,148 152,129,619 RGD:6480464
G ESR2 estrogen receptor 2 JBrowse link 14 64,226,707 64,338,631 RGD:6480464
G FASLG Fas ligand JBrowse link 1 172,659,008 172,666,876 RGD:6480464
G FBN1 fibrillin 1 JBrowse link 15 48,408,313 48,645,709 RGD:6480464
G FBN2 fibrillin 2 JBrowse link 5 128,257,909 128,538,245 RGD:6480464
G FGF1 fibroblast growth factor 1 JBrowse link 5 142,592,178 142,698,070 RGD:6480464
G FOS Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 14 75,278,828 75,282,230 RGD:6480464
G GDNF glial cell derived neurotrophic factor JBrowse link 5 37,812,677 37,840,044 RGD:6480464
G GPER1 G protein-coupled estrogen receptor 1 JBrowse link 7 1,086,807 1,093,815 RGD:6480464
G GPT glutamic--pyruvic transaminase JBrowse link 8 144,502,217 144,507,174 RGD:6480464
G GSR glutathione-disulfide reductase JBrowse link 8 30,678,061 30,727,999 RGD:6480464
G HAS1 hyaluronan synthase 1 JBrowse link 19 51,713,112 51,723,991 RGD:6480464
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 5 75,336,334 75,362,116 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 7 76,302,673 76,304,292 RGD:6480464
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:6480464
G IGF1 insulin like growth factor 1 JBrowse link 12 102,395,860 102,481,839 RGD:6480464
G IL1A interleukin 1 alpha JBrowse link 2 112,773,925 112,784,493 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G INSR insulin receptor JBrowse link 19 7,112,257 7,294,414 RGD:6480464
G KL klotho JBrowse link 13 33,016,063 33,066,143 RGD:6480464
G LDLR low density lipoprotein receptor JBrowse link 19 11,089,432 11,133,820 RGD:6480464
G LIF LIF interleukin 6 family cytokine JBrowse link 22 30,240,453 30,257,487 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 10 48,306,639 48,439,360 RGD:6480464
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 5 180,233,143 180,292,083 RGD:6480464
G MC1R melanocortin 1 receptor JBrowse link 16 89,917,879 89,920,977 RGD:6480464
G MMP2 matrix metallopeptidase 2 JBrowse link 16 55,478,830 55,506,691 RGD:6480464
G MT-CO1 mitochondrially encoded cytochrome c oxidase I JBrowse link MT 5,904 7,445 RGD:6480464
G MT-CO2 mitochondrially encoded cytochrome c oxidase II JBrowse link MT 7,586 8,269 RGD:6480464
G MT-CO3 mitochondrially encoded cytochrome c oxidase III JBrowse link MT 9,207 9,990 RGD:6480464
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,106,535 11,273,497 RGD:6480464
G MYC MYC proto-oncogene, bHLH transcription factor JBrowse link 8 127,735,434 127,742,951 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NFKB1 nuclear factor kappa B subunit 1 JBrowse link 4 102,501,266 102,617,302 RGD:6480464
G NOS1 nitric oxide synthase 1 JBrowse link 12 117,208,142 117,361,802 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 7 150,991,017 151,014,588 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PGR progesterone receptor JBrowse link 11 101,029,624 101,130,681 RGD:6480464
G PLOD3 procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 JBrowse link 7 101,205,984 101,217,581 RGD:6480464
G PML promyelocytic leukemia JBrowse link 15 73,994,673 74,047,827 RGD:6480464
G PPARA peroxisome proliferator activated receptor alpha JBrowse link 22 46,150,526 46,243,756 RGD:6480464
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 3 12,287,485 12,434,344 RGD:6480464
G PRKCD protein kinase C delta JBrowse link 3 53,161,209 53,192,717 RGD:6480464
G PTGER1 prostaglandin E receptor 1 JBrowse link 19 14,472,466 14,475,354 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G RARA retinoic acid receptor alpha JBrowse link 17 40,309,180 40,357,643 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 17 59,893,046 59,950,574 RGD:6480464
G SLC25A4 solute carrier family 25 member 4 JBrowse link 4 185,143,266 185,150,382 RGD:6480464
G SLC25A5 solute carrier family 25 member 5 JBrowse link X 119,468,444 119,471,396 RGD:6480464
G SOD3 superoxide dismutase 3 JBrowse link 4 24,795,478 24,800,845 RGD:6480464
G SQSTM1 sequestosome 1 JBrowse link 5 179,806,393 179,838,078 RGD:6480464
G SRD5A2 steroid 5 alpha-reductase 2 JBrowse link 2 31,522,480 31,665,651 RGD:6480464
G TERT telomerase reverse transcriptase JBrowse link 5 1,253,148 1,295,068 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TIMP1 TIMP metallopeptidase inhibitor 1 JBrowse link X 47,582,408 47,586,789 RGD:6480464
G TLR4 toll like receptor 4 JBrowse link 9 117,704,403 117,724,735 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TPT1 tumor protein, translationally-controlled 1 JBrowse link 13 45,333,471 45,341,284 RGD:6480464
G TXN thioredoxin JBrowse link 9 110,243,810 110,256,507 RGD:6480464
G TYRP1 tyrosinase related protein 1 JBrowse link 9 12,693,375 12,710,285 RGD:6480464
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 2 233,760,270 233,773,300 RGD:6480464
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 JBrowse link 2 233,636,477 233,773,305 RGD:6480464
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 JBrowse link 2 233,729,042 233,773,299 RGD:6480464
G UGT1A6 UDP glucuronosyltransferase family 1 member A6 JBrowse link 2 233,691,670 233,773,300 RGD:6480464
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 JBrowse link 2 233,681,938 233,773,299 RGD:6480464
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 2 233,617,645 233,773,299 RGD:6480464
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 2 233,671,898 233,773,300 RGD:6480464
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:6480464
G XIAP X-linked inhibitor of apoptosis JBrowse link X 123,859,812 123,913,979 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    role 23643
      biological role 23606
        biochemical role 22954
          metabolite 22846
            eukaryotic metabolite 22493
              plant metabolite 19294
                puerarin 96
                  puerarin xyloside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic group 21894
                              organic divalent group 21866
                                organodiyl group 21866
                                  carbonyl group 21838
                                    carbonyl compound 21838
                                      ketone 18001
                                        cyclic ketone 14404
                                          isoflavones 2659
                                            isoflavone 233
                                              puerarin 96
                                                puerarin xyloside 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.