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ONTOLOGY REPORT - ANNOTATIONS


Term:conazole antifungal agent
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Accession:CHEBI:86323 term browser browse the term
Definition:A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function.
Synonyms:related_synonym: azole antibiotic;   azole antibiotics;   conazole antifungal agents
 alt_id: CHEBI:60593


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        antimicrobial agent 17199
          antifungal agent 14718
            conazole antifungal agent 2874
              conazole antifungal drug + 780
              conazole fungicide + 2395
              diniconazole-M + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  heteroarene 15295
                                    monocyclic heteroarene 11645
                                      azole 10501
                                        conazole antifungal agent 2874
                                          conazole antifungal drug + 780
                                          conazole fungicide + 2395
                                          diniconazole-M + 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.