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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-(diethylamino)benzaldehyde
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Accession:CHEBI:86194 term browser browse the term
Definition:A member of the class of benzaldehydes carrying a diethylamino substituent at position 4.
Synonyms:related_synonym: 4-(N,N-Diethylamino)benzaldehyde;   4-Diethylaminobenzaldehyde;   Formula=C11H15NO;   InChI=1S/C11H15NO/c1-3-12(4-2)11-7-5-10(9-13)6-8-11/h5-9H,3-4H2,1-2H3;   InChIKey=MNFZZNNFORDXSV-UHFFFAOYSA-N;   SMILES=CCN(CC)c1ccc(C=O)cc1;   p-(Diethylamino)benzaldehyde;   p-Formyl-N,N-diethylaniline
 xref: CAS:120-21-8
 xref_mesh: MESH:C055506
 xref: PDBeChem:3W9;   PMID:25512087;   PMID:25554827;   Reaxys:511102


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4-(diethylamino)benzaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases activity
multiple interactions
increases oxidation		 ISO 4-(diethylamino)benzaldehyde results in decreased activity of ALDH1A1 protein
4-(diethylamino)benzaldehyde inhibits the reaction [ALDH1A1 protein results in decreased susceptibility to mafosfamide]
ALDH1A1 protein results in increased oxidation of 4-(diethylamino)benzaldehyde		 CTD PMID:8662658 PMID:16316642 PMID:25512087 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO 4-(diethylamino)benzaldehyde binds to and results in decreased activity of ALDH1A2 protein CTD PMID:25512087 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO 4-(diethylamino)benzaldehyde binds to and results in decreased activity of ALDH2 protein CTD PMID:25512087 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases oxidation ISO ALDH3A1 protein results in increased oxidation of 4-(diethylamino)benzaldehyde CTD PMID:25512087 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    role 19896
      application 19732
        refrigerant 18273
          ammonia 17827
            organic amino compound 17827
              aromatic amine 15427
                4-(diethylamino)benzaldehyde 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19867
                    p-block element atom 19867
                      carbon group element atom 19812
                        carbon atom 19807
                          organic molecular entity 19807
                            organic group 18971
                              organic divalent group 18952
                                organodiyl group 18952
                                  carbonyl group 18905
                                    carbonyl compound 18905
                                      carboxylic acid 18622
                                        carboacyl group 17704
                                          univalent carboacyl group 17704
                                            formyl group 8945
                                              aldehyde 8945
                                                arenecarbaldehyde 137
                                                  benzaldehydes 134
                                                    4-(diethylamino)benzaldehyde 4
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