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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:psorospermin
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Accession:CHEBI:8617 term browser browse the term
Definition:An organic heterotetracyclic compound that is 1,2-dihydro-6H-furo[2,3-c]xanthene substituted by a hydroxy group at position 10, a methoxy group at position 5 nad a 2-methyloxiran-2-yl group at position 2.
Synonyms:exact_synonym: (2R)-10-hydroxy-5-methoxy-2-[(2R)-2-methyloxiran-2-yl]-1,2-dihydro-6H-furo[2,3-c]xanthen-6-one
 related_synonym: Formula=C19H16O6;   InChI=1S/C19H16O6/c1-19(8-23-19)14-6-10-12(24-14)7-13(22-2)15-16(21)9-4-3-5-11(20)17(9)25-18(10)15/h3-5,7,14,20H,6,8H2,1-2H3/t14-,19-/m1/s1;   InChIKey=BBNDPXOGORGETN-AUUYWEPGSA-N;   SMILES=COc1cc2O[C@H](Cc2c2oc3c(O)cccc3c(=O)c12)[C@@]1(C)CO1
 xref: CAS:74045-97-9;   KEGG:C10090;   KNApSAcK:C00002972
 xref_mesh: MESH:C025543
 xref: PMID:7189773;   PMID:8205539;   Patent:EP1585740;   Patent:US2004102515;   Patent:US6933396;   Patent:WO2004019888;   Reaxys:5140143


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psorospermin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions ISO psorospermin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin] CTD PMID:7083125 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      application 21760
        pharmaceutical 21174
          drug 21174
            antineoplastic agent 18895
              psorospermin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    subatomic particle 22186
      composite particle 22186
        hadron 22186
          baryon 22186
            nucleon 22186
              atomic nucleus 22186
                atom 22186
                  main group element atom 22120
                    p-block element atom 22120
                      carbon group element atom 21920
                        carbon atom 21846
                          organic molecular entity 21846
                            organic molecule 21662
                              organic cyclic compound 21269
                                organic heterocyclic compound 20342
                                  organic heteromonocyclic compound 18757
                                    saturated organic heteromonocyclic parent 12139
                                      oxirane 12112
                                        epoxide 12111
                                          psorospermin 1
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