Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:psoralidin
go back to main search page
Accession:CHEBI:8616 term browser browse the term
Definition:A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 3 and 9 and a prenyl group at position 2 respectively.
Synonyms:exact_synonym: 3,9-dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c][1]benzopyran-6-one
 related_synonym: 3,9-Dihydroxy-2-prenylcoumestan;   Formula=C20H16O5;   InChI=1S/C20H16O5/c1-10(2)3-4-11-7-14-17(9-15(11)22)25-20(23)18-13-6-5-12(21)8-16(13)24-19(14)18/h3,5-9,21-22H,4H2,1-2H3;   InChIKey=YABIJLLNNFURIJ-UHFFFAOYSA-N;   SMILES=CC(C)=CCc1cc2c3oc4cc(O)ccc4c3c(=O)oc2cc1O
 xref: CAS:18642-23-4;   HMDB:HMDB0034050;   KEGG:C10523;   KNApSAcK:C00002566;   LIPID_MAPS_instance:LMPK12090007
 xref_mesh: MESH:C102768
 xref: PMID:24507928;   PMID:25216634;   Reaxys:320069;   Wikipedia:Psoralidin



show annotations for term's descendants           Sort by:
psoralidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
EXP psoralidin results in decreased activity of CYP2E1 protein
psoralidin inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]
CTD PMID:31870919 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP psoralidin results in increased expression of CYP3A4 mRNA CTD PMID:31870919 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      biological role 19808
        pharmacological role 19050
          agonist 18592
            estrogen receptor agonist 1191
              psoralidin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19730
                        carbon atom 19727
                          organic molecular entity 19727
                            organic group 18947
                              organic divalent group 18922
                                organodiyl group 18922
                                  carbonyl group 18879
                                    carbonyl compound 18879
                                      carboxylic ester 16481
                                        lactone 12523
                                          delta-lactone 3946
                                            coumestan 1782
                                              psoralidin 2
paths to the root