Term: | edoxaban tosylate |
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Accession: | CHEBI:85975
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Definition: | An organosulfonate salt obtained by combining equimolar amounts of edoxaban and 4-toluenesulfonic acid. Used (in the form of its monohydrate) for the treatment of deep vein thrombosis and pulmonary embolism. |
Synonyms: | exact_synonym: | 4-methylbenzene-1-sulfonic acid--N(1)-(5-chloropyridin-2-yl)-N(2)-{(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl}ethanediamide (1/1) |
| related_synonym: | DU 176b; Edoxaban tosilate; Formula=C31H38ClN7O7S2; InChI=1S/C24H30ClN7O4S.C7H8O3S/c1-31(2)24(36)13-4-6-15(27-20(33)21(34)30-19-7-5-14(25)11-26-19)17(10-13)28-22(35)23-29-16-8-9-32(3)12-18(16)37-23;1-6-2-4-7(5-3-6)11(8,9)10/h5,7,11,13,15,17H,4,6,8-10,12H2,1-3H3,(H,27,33)(H,28,35)(H,26,30,34);2-5H,1H3,(H,8,9,10)/t13-,15-,17+;/m0./s1; InChIKey=ZLFZITWZOYXXAW-QXXZOGQOSA-N; SMILES=Cc1ccc(cc1)S(O)(=O)=O.CN(C)C(=O)[C@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1; edoxaban 4-toluenesulfonate; edoxaban monotosylate; edoxaban p-toluenesulfonate |
| xref: | CAS:480449-71-6; PMID:21446778; PMID:24459178; PMID:25179572; PMID:25374671; PMID:25404858; PMID:25855704; Reaxys:11410837; Wikipedia:Edoxaban |
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