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ONTOLOGY REPORT - ANNOTATIONS


Term:4beta-hydroxycholesterol
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Accession:CHEBI:85778 term browser browse the term
Definition:A oxysterol that is cholesterol in which the hydrogen at the 4beta position has been replaced by a hydroxy group. A metabolite of cholesterol formed by the drug-metabolizing enzyme cytochrome P450 3A4, it is one of the major oxysterols in the human circulation.
Synonyms:exact_synonym: cholest-5-ene-3beta,4beta-diol
 related_synonym: (3beta,4beta)-cholest-5-ene-3,4-diol;   Formula=C27H46O2;   InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)20-11-12-21-19-9-10-23-25(29)24(28)14-16-27(23,5)22(19)13-15-26(20,21)4/h10,17-22,24-25,28-29H,6-9,11-16H2,1-5H3/t18-,19+,20-,21+,22+,24+,25-,26-,27-/m1/s1;   InChIKey=CZDKQKOAHAICSF-JSAMMMMSSA-N;   SMILES=CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4[C@@H](O)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C;   cholest-5-en-3beta,4beta-diol
 xref: CAS:17320-10-4 "ChemIDplus";   HMDB:HMDB0013643;   LIPID_MAPS_instance:LMST01010014 "LIPID MAPS"
 xref_mesh: MESH:C099828
 xref: PMID:11514559 "Europe PMC";   PMID:12077124 "SUBMITTER";   PMID:18279471 "Europe PMC";   PMID:18300941 "Europe PMC";   PMID:19006545 "Europe PMC";   PMID:19458613 "Europe PMC";   PMID:21728364 "Europe PMC";   PMID:8656065 "SUBMITTER"


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Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        biochemical role 19133
          metabolite 19101
            eukaryotic metabolite 18744
              algal metabolite 13301
                cholesterol 312
                  4beta-hydroxycholesterol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic molecule 19337
                              organic cyclic compound 19089
                                organic polycyclic compound 16028
                                  steroid 12769
                                    hydroxy steroid 12359
                                      3-hydroxy steroid 9986
                                        3beta-hydroxy steroid 1977
                                          3beta-hydroxy-Delta(5)-steroid 1837
                                            cholesterol 312
                                              oxysterol 91
                                                4beta-hydroxycholesterol 0
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