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ONTOLOGY REPORT - ANNOTATIONS


Term:satraplatin
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Accession:CHEBI:85609 term browser browse the term
Definition:A platinum coordination entity that consists of a central platunum atom bound to chloro (x2), acetate (x2), amino, and cyclohexylamino groups. Used for treatment of advanced prostate cancer.
Synonyms:exact_synonym: bis(acetato-kappaO)(ammine)dichloro(cyclohexanamine)platinum
 related_synonym: BMY 45594;   Bis-acetatoamminedichlorocyclohexylamine platinum(IV);   Formula=C10H22Cl2N2O4Pt;   InChI=1S/C6H13N.2C2H4O2.2ClH.H3N.Pt/c7-6-4-2-1-3-5-6;2*1-2(3)4;;;;/h6H,1-5,7H2;2*1H3,(H,3,4);2*1H;1H3;/q;;;;;;+4/p-4;   InChIKey=CKNPWBAXEKSCRG-UHFFFAOYSA-J;   JM-216;   JM216;   SMILES=CC(=O)O[Pt--]([NH3+])(Cl)(Cl)([NH2+]C1CCCCC1)OC(C)=O
 xref: CAS:129580-63-8 "ChemIDplus";   KEGG:D05807
 xref_mesh: MESH:C081294
 xref: PMID:21481618 "Europe PMC";   PMID:22643969 "Europe PMC";   PMID:23429330 "Europe PMC";   PMID:23433892 "Europe PMC";   PMID:23684781 "Europe PMC";   PMID:25382189 "Europe PMC";   PMID:25435590 "Europe PMC";   PMID:25556988 "Europe PMC";   PMID:9658208 "Europe PMC";   Reaxys:22320762 "Reaxys";   Wikipedia:Satraplatin


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satraplatin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:6480464
G Atp7b ATPase copper transporting beta JBrowse link 16 74,865,516 74,944,935 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      application 19232
        pharmaceutical 19094
          drug 19094
            antineoplastic agent 16568
              satraplatin 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  metal atom 17050
                    transition element atom 16559
                      d-block element atom 16548
                        nickel group element atom 10109
                          platinum 8386
                            platinum molecular entity 8386
                              platinum coordination entity 8386
                                satraplatin 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.