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Accession:CHEBI:85572 term browser browse the term
Definition:A member of the class of pyridopyrimidines that is an mTOR inhibitor and shows anti-tumour properties.
Synonyms:exact_synonym: (5-{2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-(morpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol
 related_synonym: Formula=C25H31N5O4;   InChI=1S/C25H31N5O4/c1-16-13-30(14-17(2)34-16)25-27-23-20(24(28-25)29-8-10-33-11-9-29)5-6-21(26-23)18-4-7-22(32-3)19(12-18)15-31/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17+;   InChIKey=RFSMUFRPPYDYRD-CALCHBBNSA-N;   KU-63794;   KU0063794;   SMILES=COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1C[C@H](C)O[C@H](C)C1)N1CCOCC1
 xref: CAS:938440-64-3 "ChemIDplus";   LINCS:LSM-5754
 xref_mesh: MESH:C541932
 xref: PMID:19402821 "Europe PMC";   PMID:23349989 "Europe PMC";   PMID:25618298 "Europe PMC";   PMID:25651869 "Europe PMC";   Reaxys:12909210 "Reaxys"

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Ku-0063794 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:6480464
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:6480464

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  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            antineoplastic agent 16550
              Ku-0063794 3
Path 2
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  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                carbocyclic compound 17501
                                  benzenoid aromatic compound 17022
                                    benzenes 16737
                                      methoxybenzenes 805
                                        monomethoxybenzene 717
                                          Ku-0063794 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.