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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:11,12-saturated fatty acyl-CoA
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Accession:CHEBI:85348 term browser browse the term
Definition:Any fatty acyl-CoA in which the 11-12 bond of the fatty acyl group is saturated.
Synonyms:related_synonym: Formula=C33H57N7O17P3SR;   SMILES=CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCCCCCCCCCC[*]
 cyclic_relationship: is_conjugate_acid_of CHEBI:84948


show annotations for term's descendants           Sort by:
 
myristoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbi diazepam binding inhibitor, acyl-CoA binding protein affects binding ISO S-tetradecanoyl-coenzyme A binds to DBI protein CTD PMID:17044054 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
palmitoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases metabolic processing
multiple interactions
ISO ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A
[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]
CTD PMID:10497882 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis EXP CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A CTD PMID:8611161 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions EXP valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Palmitoyl Coenzyme A] CTD PMID:19854160 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] CTD PMID:16214399 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression ISO Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA; Palmitoyl Coenzyme A results in decreased expression of HNF4A protein CTD PMID:17992261 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein
Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Enalapril inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gedunin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]; Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Pyrazinamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Saccharin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; salicylamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolmetin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]
CTD PMID:11139385 PMID:18812576 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Shbg sex hormone binding globulin decreases expression ISO Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA; Palmitoyl Coenzyme A results in decreased expression of SHBG protein CTD PMID:17992261 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
stearoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO stearoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein CTD PMID:10542059 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO stearoyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO stearoyl-coenzyme A binds to and results in increased activity of PPARG protein CTD PMID:11139385 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      chemical role 19336
        donor 18644
          acyl donor 28
            acyl-CoA 28
              fatty acyl-CoA 16
                11,12-saturated fatty acyl-CoA 10
                  (13Z)-3-oxodocosenoyl-CoA 0
                  (13Z)-3-oxoicosenoyl-CoA 0
                  (13Z,16Z,19Z)-3-oxodocosatrienoyl-CoA 0
                  (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA 0
                  (2E,13Z)-docosadienoyl-CoA 0
                  (2E,13Z)-icosadienoyl-CoA 0
                  (2E,9E)-octadecadienoyl-CoA 0
                  (2E,9Z)-hexadecadienoyl-CoA 0
                  (2E,9Z)-octadecadienoyl-CoA 0
                  (2S)-2-methylpentadecanoyl-CoA 0
                  (3E,5Z)-tetradecadienoyl-CoA 0
                  (3R,13Z)-3-hydroxydocosenoyl-CoA 0
                  (3R,13Z)-3-hydroxyicosenoyl-CoA 0
                  (5E)-tetradecenoyl-CoA 0
                  (5Z)-tetradecenoyl-CoA 0
                  (6Z)-hexadecenoyl-CoA 0
                  (6Z)-octadecenoyl-CoA 0
                  (9Z)-heptadecenoyl-CoA 0
                  (9Z)-pentadecenoyl-CoA 0
                  (E)-2,3-didehydropristanoyl-CoA 0
                  (E)-isoheptadec-2-enoyl-CoA 0
                  (E)-isopentadec-2-enoyl-CoA 0
                  (R)-3-hydroxybehenoyl-CoA 0
                  (R)-3-hydroxyicosanoyl-CoA 0
                  (R)-3-hydroxypalmitoyl-CoA 0
                  (R)-3-hydroxystearoyl-CoA 0
                  (R)-3-hydroxytetradecanoyl-CoA 0
                  (S)-3-hydroxypalmitoyl-CoA 0
                  12-methyloctadecanoyl-CoA 0
                  15-hydroxypentadecanoyl-CoA 0
                  16-hydroxyhexadecanoyl-CoA 0
                  2-hydroxybehenoyl-CoA 0
                  2-hydroxyhexadecanoyl-CoA + 0
                  2-hydroxyphytanoyl-CoA 0
                  2-hydroxystearoyl-CoA 0
                  2-methylhexadecanoyl-CoA 0
                  3-hydroxyisoheptadecanoyl-CoA 0
                  3-hydroxyisopentadecanoyl-CoA 0
                  3-hydroxyoctadecanoyl-CoA + 0
                  3-hydroxypristanoyl-CoA 0
                  3-hydroxytetradecanoyl-CoA 0
                  3-oxodocosanoyl-CoA 0
                  3-oxodotriacontanoyl-CoA 0
                  3-oxoisoheptadecanoyl-CoA 0
                  3-oxoisooctadecanoyl-CoA 0
                  3-oxoisopentadecanoyl-CoA 0
                  3-oxopristanoyl-CoA 0
                  4,8,12-trimethyltridecanoyl-CoA 0
                  cis,cis-tetradeca-5,8-dienoyl-CoA 0
                  cis-tetradec-3-enoyl-CoA 0
                  erucoyl-CoA 0
                  heptadecanoyl-CoA 0
                  hexadec-2-enoyl-CoA + 0
                  hexadecanoyl-CoA 0
                  icosanoyl-CoA + 0
                  isoheptadecanoyl-CoA 0
                  isomyristoyl-CoA 0
                  isopalmitoyl-CoA 0
                  isopentadecanoyl-CoA 0
                  myristoyl-CoA + 3
                  nonadecanoyl-CoA 0
                  palmitoleoyl-CoA 0
                  palmitoyl-CoA + 9
                  pentadecanoyl-CoA 0
                  pristanoyl-CoA + 0
                  stearoyl-CoA 3
                  tetradecanoyls-CoA 0
                  trans-2-docosenoyl-CoA 0
                  trans-2-heptadecenoyl-CoA 0
                  trans-2-icosenoyl-CoA 0
                  trans-2-octadecenoyl-CoA 0
                  trans-2-pentadecenoyl-CoA 0
                  trans-tetradec-2-enoyl-CoA 0
                  tridecanoyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      chalcogen 19460
                        oxygen atom 19436
                          oxygen molecular entity 19436
                            hydroxides 19175
                              oxoacid 18488
                                pnictogen oxoacid 10688
                                  phosphorus oxoacid 9669
                                    phosphoric acids 8466
                                      phosphoric acid 8466
                                        phosphoric acid derivative 8171
                                          phosphate 8170
                                            organic phosphate 8169
                                              carbohydrate phosphate 1734
                                                phospho sugar 1659
                                                  aldose phosphate 1657
                                                    aldopentose phosphate 1651
                                                      ribose phosphate 1646
                                                        ribonucleotide 1607
                                                          purine ribonucleotide 1580
                                                            adenyl ribonucleotide 1283
                                                              adenosine phosphate 274
                                                                adenosine 5'-phosphate 273
                                                                  ADP 87
                                                                    coenzyme A 28
                                                                      acyl-CoA 28
                                                                        fatty acyl-CoA 16
                                                                          11,12-saturated fatty acyl-CoA 10
                                                                            (13Z)-3-oxodocosenoyl-CoA 0
                                                                            (13Z)-3-oxoicosenoyl-CoA 0
                                                                            (13Z,16Z,19Z)-3-oxodocosatrienoyl-CoA 0
                                                                            (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA 0
                                                                            (2E,13Z)-docosadienoyl-CoA 0
                                                                            (2E,13Z)-icosadienoyl-CoA 0
                                                                            (2E,9E)-octadecadienoyl-CoA 0
                                                                            (2E,9Z)-hexadecadienoyl-CoA 0
                                                                            (2E,9Z)-octadecadienoyl-CoA 0
                                                                            (2S)-2-methylpentadecanoyl-CoA 0
                                                                            (3E,5Z)-tetradecadienoyl-CoA 0
                                                                            (3R,13Z)-3-hydroxydocosenoyl-CoA 0
                                                                            (3R,13Z)-3-hydroxyicosenoyl-CoA 0
                                                                            (5E)-tetradecenoyl-CoA 0
                                                                            (5Z)-tetradecenoyl-CoA 0
                                                                            (6Z)-hexadecenoyl-CoA 0
                                                                            (6Z)-octadecenoyl-CoA 0
                                                                            (9Z)-heptadecenoyl-CoA 0
                                                                            (9Z)-pentadecenoyl-CoA 0
                                                                            (E)-2,3-didehydropristanoyl-CoA 0
                                                                            (E)-isoheptadec-2-enoyl-CoA 0
                                                                            (E)-isopentadec-2-enoyl-CoA 0
                                                                            (R)-3-hydroxybehenoyl-CoA 0
                                                                            (R)-3-hydroxyicosanoyl-CoA 0
                                                                            (R)-3-hydroxypalmitoyl-CoA 0
                                                                            (R)-3-hydroxystearoyl-CoA 0
                                                                            (R)-3-hydroxytetradecanoyl-CoA 0
                                                                            (S)-3-hydroxypalmitoyl-CoA 0
                                                                            12-methyloctadecanoyl-CoA 0
                                                                            15-hydroxypentadecanoyl-CoA 0
                                                                            16-hydroxyhexadecanoyl-CoA 0
                                                                            2-hydroxybehenoyl-CoA 0
                                                                            2-hydroxyhexadecanoyl-CoA + 0
                                                                            2-hydroxyphytanoyl-CoA 0
                                                                            2-hydroxystearoyl-CoA 0
                                                                            2-methylhexadecanoyl-CoA 0
                                                                            3-hydroxyisoheptadecanoyl-CoA 0
                                                                            3-hydroxyisopentadecanoyl-CoA 0
                                                                            3-hydroxyoctadecanoyl-CoA + 0
                                                                            3-hydroxypristanoyl-CoA 0
                                                                            3-hydroxytetradecanoyl-CoA 0
                                                                            3-oxodocosanoyl-CoA 0
                                                                            3-oxodotriacontanoyl-CoA 0
                                                                            3-oxoisoheptadecanoyl-CoA 0
                                                                            3-oxoisooctadecanoyl-CoA 0
                                                                            3-oxoisopentadecanoyl-CoA 0
                                                                            3-oxopristanoyl-CoA 0
                                                                            4,8,12-trimethyltridecanoyl-CoA 0
                                                                            cis,cis-tetradeca-5,8-dienoyl-CoA 0
                                                                            cis-tetradec-3-enoyl-CoA 0
                                                                            erucoyl-CoA 0
                                                                            heptadecanoyl-CoA 0
                                                                            hexadec-2-enoyl-CoA + 0
                                                                            hexadecanoyl-CoA 0
                                                                            icosanoyl-CoA + 0
                                                                            isoheptadecanoyl-CoA 0
                                                                            isomyristoyl-CoA 0
                                                                            isopalmitoyl-CoA 0
                                                                            isopentadecanoyl-CoA 0
                                                                            myristoyl-CoA + 3
                                                                            nonadecanoyl-CoA 0
                                                                            palmitoleoyl-CoA 0
                                                                            palmitoyl-CoA + 9
                                                                            pentadecanoyl-CoA 0
                                                                            pristanoyl-CoA + 0
                                                                            stearoyl-CoA 3
                                                                            tetradecanoyls-CoA 0
                                                                            trans-2-docosenoyl-CoA 0
                                                                            trans-2-heptadecenoyl-CoA 0
                                                                            trans-2-icosenoyl-CoA 0
                                                                            trans-2-octadecenoyl-CoA 0
                                                                            trans-2-pentadecenoyl-CoA 0
                                                                            trans-tetradec-2-enoyl-CoA 0
                                                                            tridecanoyl-CoA 0
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