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Term:potassium clavulanate
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Accession:CHEBI:85264 term browser browse the term
Definition:A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases.
Synonyms:exact_synonym: potassium (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
 related_synonym: CVA;   Formula=C8H8KNO5;   InChI=1S/C8H9NO5.K/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h1,6-7,10H,2-3H2,(H,12,13);/q;+1/p-1/b4-1-;/t6-,7-;/m1./s1;   InChIKey=ABVRVIZBZKUTMK-JSYANWSFSA-M;   SMILES=[K+].OC\\C=C1/O[C@@H]2CC(=O)N2[C@H]1C([O-])=O
 xref: CAS:61177-45-5 "ChemIDplus";   CAS:61177-45-5 "KEGG DRUG";   DrugBank:DB00766;   KEGG:D02370;   Reaxys:4773605 "Reaxys";   Wikipedia:Clavulanic_Acid

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  CHEBI ontology 19654
    role 19598
      biological role 19596
        antimicrobial agent 17143
          potassium clavulanate 0
            Augmentin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic ion 7853
                              organic anion 2204
                                carboxylic acid anion 1810
                                  monocarboxylic acid anion 1469
                                    clavulanate 0
                                      potassium clavulanate 0
                                        Augmentin 0
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