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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:potassium clavulanate
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Accession:CHEBI:85264 term browser browse the term
Definition:A potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes and has only weak anitbiotic activity when administered alone. However it can be used in combination with amoxicillin trihydrate (under the trade name Augmentin) for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases.
Synonyms:exact_synonym: potassium (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate
 related_synonym: CVA;   Formula=C8H8KNO5;   InChI=1S/C8H9NO5.K/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4;/h1,6-7,10H,2-3H2,(H,12,13);/q;+1/p-1/b4-1-;/t6-,7-;/m1./s1;   InChIKey=ABVRVIZBZKUTMK-JSYANWSFSA-M;   SMILES=[K+].OC\\C=C1/O[C@@H]2CC(=O)N2[C@H]1C([O-])=O
 xref: CAS:61177-45-5;   DrugBank:DB00766;   KEGG:D02370;   Reaxys:4773605;   Wikipedia:Clavulanic_Acid


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Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        antimicrobial agent 17818
          potassium clavulanate 0
            Augmentin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic ion 9185
                              organic anion 3104
                                carboxylic acid anion 2436
                                  monocarboxylic acid anion 1558
                                    clavulanate 0
                                      potassium clavulanate 0
                                        Augmentin 0
paths to the root