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ONTOLOGY REPORT - ANNOTATIONS


Term:2,5-hexanedione
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Accession:CHEBI:85014 term browser browse the term
Definition:A diketone that is hexane substituted by oxo groups at positions 2 and 5. It is a toxic metabolite of hexane and of 2-hexanone
Synonyms:related_synonym: 1,2-Diacetylethane;   2,5-Diketohexane;   2,5-Hexadione;   Acetonyl acetone;   CH3COCH2CH2COCH3;   Formula=C6H10O2;   InChI=1S/C6H10O2/c1-5(7)3-4-6(2)8/h3-4H2,1-2H3;   InChIKey=OJVAMHKKJGICOG-UHFFFAOYSA-N;   NSC 7621;   SMILES=CC(=O)CCC(C)=O;   acetonylacetone;   alpha,beta-diacetylethane;   hexane-2,5-dione
 xref: CAS:110-13-4
 xref_mesh: MESH:C011269
 xref: MetaCyc:CPD-15521;   PMID:1781736;   PMID:24634916;   PMID:25549948;   Reaxys:506525;   Wikipedia:Hexane-2\,5-dione


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2,5-hexanedione term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G 5031439G07Rik RIKEN cDNA 5031439G07 gene JBrowse link 15 84,943,936 84,987,971 RGD:6480464
G Abi2 abl-interactor 2 JBrowse link 1 60,405,768 60,481,945 RGD:6480464
G Aco2 aconitase 2, mitochondrial JBrowse link 15 81,872,463 81,915,137 RGD:6480464
G Alox8 arachidonate 8-lipoxygenase JBrowse link 11 69,183,885 69,197,843 RGD:6480464
G Angptl4 angiopoietin-like 4 JBrowse link 17 33,774,900 33,781,575 RGD:6480464
G AW554918 expressed sequence AW554918 JBrowse link 18 25,168,730 25,467,321 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2l14 BCL2-like 14 (apoptosis facilitator) JBrowse link 6 134,396,329 134,438,724 RGD:6480464
G Bdnf brain derived neurotrophic factor JBrowse link 2 109,674,700 109,727,043 RGD:6480464
G Bfar bifunctional apoptosis regulator JBrowse link 16 13,671,858 13,703,612 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Ccdc171 coiled-coil domain containing 171 JBrowse link 4 83,525,409 83,866,143 RGD:6480464
G Ccdc191 coiled-coil domain containing 191 JBrowse link 16 43,889,809 43,964,314 RGD:6480464
G Cdin1 CDAN1 interacting nuclease 1 JBrowse link 2 115,580,907 115,778,774 RGD:6480464
G Cep112 centrosomal protein 112 JBrowse link 11 108,425,215 108,860,615 RGD:6480464
G Cfap221 cilia and flagella associated protein 221 JBrowse link 1 119,923,340 120,006,958 RGD:6480464
G Ckmt1 creatine kinase, mitochondrial 1, ubiquitous JBrowse link 2 121,357,773 121,363,737 RGD:6480464
G Clca2 chloride channel accessory 2 JBrowse link 3 145,070,260 145,099,443 RGD:6480464
G Clu clusterin JBrowse link 14 65,968,483 65,981,548 RGD:6480464
G Ctxn1 cortexin 1 JBrowse link 8 4,257,646 4,259,274 RGD:6480464
G Dcn decorin JBrowse link 10 97,479,500 97,518,163 RGD:6480464
G Dennd1a DENN/MADD domain containing 1A JBrowse link 2 37,798,990 38,287,410 RGD:6480464
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 JBrowse link 3 152,181,580 152,210,432 RGD:6480464
G Dpp7 dipeptidylpeptidase 7 JBrowse link 2 25,352,290 25,356,389 RGD:6480464
G Dpysl2 dihydropyrimidinase-like 2 JBrowse link 14 66,802,864 66,911,041 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:6480464
G Erc1 ELKS/RAB6-interacting/CAST family member 1 JBrowse link 6 119,570,796 119,848,184 RGD:6480464
G Fasl Fas ligand (TNF superfamily, member 6) JBrowse link 1 161,780,691 161,788,495 RGD:6480464
G Fasn fatty acid synthase JBrowse link 11 120,805,958 120,825,166 RGD:6480464
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide JBrowse link 1 171,229,572 171,234,349 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha JBrowse link 6 67,035,096 67,037,407 RGD:6480464
G Gas2 growth arrest specific 2 JBrowse link 7 51,861,791 51,995,005 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 11 102,887,336 102,897,200 RGD:6480464
G Ghsr growth hormone secretagogue receptor JBrowse link 3 27,371,351 27,379,235 RGD:6480464
G Glud1 glutamate dehydrogenase 1 JBrowse link 14 34,310,727 34,345,033 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 16 38,089,001 38,246,084 RGD:6480464
G Gsn gelsolin JBrowse link 2 35,256,359 35,307,902 RGD:6480464
G Gstp1 glutathione S-transferase, pi 1 JBrowse link 19 4,035,411 4,037,912 RGD:6480464
G Hdgfl1 HDGF like 1 JBrowse link 13 26,768,172 26,770,165 RGD:6480464
G Hspa1b heat shock protein 1B JBrowse link 17 34,956,429 34,959,238 RGD:6480464
G Ier3 immediate early response 3 JBrowse link 17 35,821,713 35,822,911 RGD:6480464
G Ift81 intraflagellar transport 81 JBrowse link 5 122,540,265 122,614,546 RGD:6480464
G Igfbp3 insulin-like growth factor binding protein 3 JBrowse link 11 7,206,086 7,215,498 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Ina internexin neuronal intermediate filament protein, alpha JBrowse link 19 47,014,681 47,025,327 RGD:6480464
G Itgam integrin alpha M JBrowse link 7 128,062,640 128,118,491 RGD:6480464
G Itgb1 integrin beta 1 (fibronectin receptor beta) JBrowse link 8 128,685,654 128,733,579 RGD:6480464
G Kif6 kinesin family member 6 JBrowse link 17 49,615,098 49,909,847 RGD:6480464
G Kit KIT proto-oncogene receptor tyrosine kinase JBrowse link 5 75,574,987 75,656,722 RGD:6480464
G Loxl1 lysyl oxidase-like 1 JBrowse link 9 58,287,723 58,313,212 RGD:6480464
G Lrrc6 leucine rich repeat containing 6 (testis) JBrowse link 15 66,379,858 66,500,921 RGD:6480464
G Lrrc69 leucine rich repeat containing 69 JBrowse link 4 14,623,622 14,808,379 RGD:6480464
G Lyz2 lysozyme 2 JBrowse link 10 117,277,541 117,282,272 RGD:6480464
G Macrod1 mono-ADP ribosylhydrolase 1 JBrowse link 19 7,056,728 7,198,062 RGD:6480464
G Map1a microtubule-associated protein 1 A JBrowse link 2 121,289,590 121,310,832 RGD:6480464
G Map1b microtubule-associated protein 1B JBrowse link 13 99,421,464 99,516,602 RGD:6480464
G Map2 microtubule-associated protein 2 JBrowse link 1 66,175,202 66,442,583 RGD:6480464
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 13 111,746,428 111,818,269 RGD:6480464
G Mapt microtubule-associated protein tau JBrowse link 11 104,229,409 104,332,090 RGD:6480464
G Mdh1 malate dehydrogenase 1, NAD (soluble) JBrowse link 11 21,556,692 21,571,934 RGD:6480464
G Mfap3l microfibrillar-associated protein 3-like JBrowse link 8 60,632,825 60,676,731 RGD:6480464
G Mir10b microRNA 10b JBrowse link 2 74,726,070 74,726,137 RGD:6480464
G Mir1224 microRNA 1224 JBrowse link 16 20,604,452 20,604,536 RGD:6480464
G Mir125a microRNA 125a JBrowse link 17 17,830,812 17,830,879 RGD:6480464
G Mir130b microRNA 130b JBrowse link 16 17,124,061 17,124,142 RGD:6480464
G Mir134 microRNA 134 JBrowse link 12 109,734,139 109,734,209 RGD:6480464
G Mir155 microRNA 155 JBrowse link 16 84,714,140 84,714,204 RGD:6480464
G Mir183 microRNA 183 JBrowse link 6 30,169,668 30,169,737 RGD:6480464
G Mir193a microRNA 193a JBrowse link 11 79,711,969 79,712,034 RGD:6480464
G Mir194-2 microRNA 194-2 JBrowse link 19 6,264,643 6,264,728 RGD:6480464
G Mir196a-1 microRNA 196a-1 JBrowse link 11 96,265,164 96,265,265 RGD:6480464
G Mir196a-2 microRNA 196a-2 JBrowse link 15 102,973,350 102,973,434 RGD:6480464
G Mir199a-2 microRNA 199a-2 JBrowse link 1 162,217,814 162,217,923 RGD:6480464
G Mir200c microRNA 200c JBrowse link 6 124,718,322 124,718,390 RGD:6480464
G Mir202 microRNA 202 JBrowse link 7 139,957,689 139,957,760 RGD:6480464
G Mir206 microRNA 206 JBrowse link 1 20,679,010 20,679,082 RGD:6480464
G Mir208a microRNA 208a JBrowse link 14 54,949,060 54,949,142 RGD:6480464
G Mir20a microRNA 20a JBrowse link 14 115,044,157 115,044,263 RGD:6480464
G Mir212 microRNA 212 JBrowse link 11 75,173,388 75,173,478 RGD:6480464
G Mir21a microRNA 21a JBrowse link 11 86,584,067 86,584,158 RGD:6480464
G Mir22 microRNA 22 JBrowse link 11 75,463,716 75,463,810 RGD:6480464
G Mir223 microRNA 223 JBrowse link X 96,242,817 96,242,926 RGD:6480464
G Mir224 microRNA 224 JBrowse link X 72,261,031 72,261,112 RGD:6480464
G Mir27a microRNA 27a JBrowse link 8 84,208,672 84,208,758 RGD:6480464
G Mir27b microRNA 27b JBrowse link 13 63,300,712 63,300,784 RGD:6480464
G Mir30a microRNA 30a JBrowse link 1 23,272,269 23,272,339 RGD:6480464
G Mir32 microRNA 32 JBrowse link 4 56,895,229 56,895,298 RGD:6480464
G Mir320 microRNA 320 JBrowse link 14 70,443,510 70,443,591 RGD:6480464
G Mir323 microRNA 323 JBrowse link 12 109,712,508 109,712,593 RGD:6480464
G Mir326 microRNA 326 JBrowse link 7 99,552,269 99,552,363 RGD:6480464
G Mir33 microRNA 33 JBrowse link 15 82,198,122 82,198,190 RGD:6480464
G Mir330 microRNA 330 JBrowse link 7 19,181,465 19,181,562 RGD:6480464
G Mir331 microRNA 331 JBrowse link 10 93,963,768 93,963,863 RGD:6480464
G Mir339 microRNA 339 JBrowse link 5 139,369,650 139,369,745 RGD:6480464
G Mir345 microRNA 345 JBrowse link 12 108,836,973 108,837,068 RGD:6480464
G Mir370 microRNA 370 JBrowse link 12 109,618,258 109,618,336 RGD:6480464
G Mir375 microRNA 375 JBrowse link 1 74,900,658 74,900,721 RGD:6480464
G Mir412 microRNA 412 JBrowse link 12 109,743,289 109,743,368 RGD:6480464
G Mir423 microRNA 423 JBrowse link 11 77,078,064 77,078,172 RGD:6480464
G Mir433 microRNA 433 JBrowse link 12 109,591,715 109,591,838 RGD:6480464
G Mir450-1 microRNA 450-1 JBrowse link X 53,048,154 53,048,244 RGD:6480464
G Mir487b microRNA 487b JBrowse link 12 109,727,333 109,727,414 RGD:6480464
G Mir488 microRNA 488 JBrowse link 1 158,505,625 158,505,733 RGD:6480464
G Mir497 microRNA 497 JBrowse link 11 70,234,717 70,234,800 RGD:6480464
G Mir503 microRNA 503 JBrowse link X 53,053,984 53,054,054 RGD:6480464
G Mir541 microRNA 541 JBrowse link 12 109,742,409 109,742,498 RGD:6480464
G Mir542 microRNA 542 JBrowse link X 53,049,403 53,049,487 RGD:6480464
G Mir551b microRNA 551b JBrowse link 3 29,416,823 29,416,920 RGD:6480464
G Mir582 microRNA 582 JBrowse link 13 109,324,744 109,324,824 RGD:6480464
G Mir652 microRNA 652 JBrowse link X 142,739,000 142,739,097 RGD:6480464
G Mir653 microRNA 653 JBrowse link 6 3,721,301 3,721,385 RGD:6480464
G Mir665 microRNA 665 JBrowse link 12 109,586,314 109,586,407 RGD:6480464
G Mir675 microRNA 675 JBrowse link 7 142,577,064 142,577,147 RGD:6480464
G Mir760 microRNA 760 JBrowse link 3 122,293,585 122,293,703 RGD:6480464
G Mir770 microRNA 770 JBrowse link 12 109,563,692 109,563,785 RGD:6480464
G Mir873a microRNA 873a JBrowse link 4 36,668,510 36,668,586 RGD:6480464
G Mir877 microRNA 877 JBrowse link 17 35,960,730 35,960,814 RGD:6480464
G Mirlet7b microRNA let7b JBrowse link 15 85,707,319 85,707,403 RGD:6480464
G Mirlet7i microRNA let7i JBrowse link 10 122,985,640 122,985,724 RGD:6480464
G Mtm1 X-linked myotubular myopathy gene 1 JBrowse link X 71,210,767 71,315,413 RGD:6480464
G Napa N-ethylmaleimide sensitive fusion protein attachment protein alpha JBrowse link 7 16,098,202 16,117,982 RGD:6480464
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 JBrowse link 1 92,439,486 92,473,825 RGD:6480464
G Nefh neurofilament, heavy polypeptide JBrowse link 11 4,938,754 4,948,064 RGD:6480464
G Nefl neurofilament, light polypeptide JBrowse link 14 68,083,863 68,089,095 RGD:6480464
G Nefm neurofilament, medium polypeptide JBrowse link 14 68,119,545 68,125,004 RGD:6480464
G Nsf N-ethylmaleimide sensitive fusion protein JBrowse link 11 103,821,782 103,954,056 RGD:6480464
G Nupr1l nuclear protein transcriptional regulator 1 like JBrowse link 5 129,908,540 129,913,788 RGD:6480464
G Pdia3 protein disulfide isomerase associated 3 JBrowse link 2 121,413,902 121,438,687 RGD:6480464
G Pdlim3 PDZ and LIM domain 3 JBrowse link 8 45,885,487 45,919,635 RGD:6480464
G Pgam1 phosphoglycerate mutase 1 JBrowse link 19 41,911,871 41,918,665 RGD:6480464
G Phospho1 phosphatase, orphan 1 JBrowse link 11 95,824,500 95,832,140 RGD:6480464
G Pim1 proviral integration site 1 JBrowse link 17 29,490,785 29,496,111 RGD:6480464
G Pkm pyruvate kinase, muscle JBrowse link 9 59,656,576 59,679,372 RGD:6480464
G Pou2f1 POU domain, class 2, transcription factor 1 JBrowse link 1 165,865,150 166,002,749 RGD:6480464
G Prkcsh protein kinase C substrate 80K-H JBrowse link 9 22,002,988 22,014,245 RGD:6480464
G Ptgds prostaglandin D2 synthase (brain) JBrowse link 2 25,466,709 25,470,110 RGD:6480464
G Pygb brain glycogen phosphorylase JBrowse link 2 150,786,796 150,831,748 RGD:6480464
G Pygm muscle glycogen phosphorylase JBrowse link 19 6,384,408 6,398,464 RGD:6480464
G Ralgapa2 Ral GTPase activating protein, alpha subunit 2 (catalytic) JBrowse link 2 146,239,876 146,512,254 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Rtkn2 rhotekin 2 JBrowse link 10 67,979,566 68,058,429 RGD:6480464
G S100z S100 calcium binding protein, zeta JBrowse link 13 95,477,301 95,478,655 RGD:6480464
G Sclt1 sodium channel and clathrin linker 1 JBrowse link 3 41,626,705 41,742,551 RGD:6480464
G Septin8 septin 8 JBrowse link 11 53,519,397 53,549,605 RGD:6480464
G Sh2d4a SH2 domain containing 4A JBrowse link 8 68,276,528 68,347,704 RGD:6480464
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 15 89,493,013 89,560,261 RGD:6480464
G Sil1 endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae) JBrowse link 18 35,266,396 35,499,390 RGD:6480464
G Slc10a7 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 JBrowse link 8 78,509,323 78,734,012 RGD:6480464
G Sltm SAFB-like, transcription modulator JBrowse link 9 70,542,177 70,592,237 RGD:6480464
G Sod3 superoxide dismutase 3, extracellular JBrowse link 5 52,363,804 52,369,738 RGD:6480464
G Sppl3 signal peptide peptidase 3 JBrowse link 5 115,011,524 115,098,790 RGD:6480464
G Sptan1 spectrin alpha, non-erythrocytic 1 JBrowse link 2 29,965,560 30,031,451 RGD:6480464
G Stmn1 stathmin 1 JBrowse link 4 134,468,320 134,473,843 RGD:6480464
G Strbp spermatid perinuclear RNA binding protein JBrowse link 2 37,569,868 37,703,878 RGD:6480464
G Styxl1 serine/threonine/tyrosine interacting-like 1 JBrowse link 5 135,747,220 135,778,424 RGD:6480464
G Tax1bp1 Tax1 (human T cell leukemia virus type I) binding protein 1 JBrowse link 6 52,713,692 52,766,780 RGD:6480464
G Tbc1d5 TBC1 domain family, member 5 JBrowse link 17 50,733,124 51,181,199 RGD:6480464
G Tmem192 transmembrane protein 192 JBrowse link 8 64,947,149 64,969,036 RGD:6480464
G Tpi1 triosephosphate isomerase 1 JBrowse link 6 124,810,586 124,814,158 RGD:6480464
G Uba1 ubiquitin-like modifier activating enzyme 1 JBrowse link X 20,658,302 20,683,179 RGD:6480464
G Ubn2 ubinuclein 2 JBrowse link 6 38,433,925 38,512,763 RGD:6480464
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 JBrowse link 7 120,635,189 120,659,523 RGD:6480464
G Vim vimentin JBrowse link 2 13,574,311 13,582,826 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 42,059,613 42,109,664 RGD:6480464
G Zfp169 zinc finger protein 169 JBrowse link 13 48,480,763 48,513,493 RGD:6480464
G Zfp407 zinc finger protein 407 JBrowse link 18 84,207,701 84,589,539 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21322
    role 21309
      biological role 21307
        aetiopathogenetic role 20208
          neurotoxin 17871
            2,5-hexanedione 167
Path 2
Term Annotations click to browse term
  CHEBI ontology 21322
    subatomic particle 21318
      composite particle 21318
        hadron 21318
          baryon 21318
            nucleon 21318
              atomic nucleus 21318
                atom 21318
                  main group element atom 21193
                    p-block element atom 21193
                      carbon group element atom 20991
                        carbon atom 20881
                          organic molecular entity 20881
                            organic group 19225
                              organic divalent group 19215
                                organodiyl group 19215
                                  carbonyl group 19189
                                    carbonyl compound 19189
                                      ketone 16338
                                        diketone 1145
                                          2,5-hexanedione 167
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.